Clinical trials: Traumatic Fracture, open to volunteers
Distal Radius Fractures, Rehabilitation
Evaluation of Limb Function and Perception in Rehabilitation After Traumatic Wrist Fracture Surgery
The goal of this observational study is to assess the functional and perceptual alterations of the affected limb during rehabilitation in adult orthopedic patients who underwent surgical treatment for distal radius fractures.
- Conditions
- Distal Radius Fractures, Rehabilitation, Body Perception
- Trial name
- NCT06866340
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis
Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty
The purpose of this post-market clinical follow up study is to assess the safety and effectiveness of the SYMBOL range of medical devices.
- Conditions
- Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis, Hip Arthritis, Femoral Neck Fractures
- Trial name
- NCT05227924
- Testing
- Total hip arthroplasty (primary or revision)
- Where
- 9 sites in France
- Volunteers
- 747 people
- Sponsor
- Dedienne Sante S.A.S.
Elbow Joint Destruction, Post-traumatic Lesions
Clinical Outcomes Study of the Nexel Total Elbow
The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.
- Conditions
- Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis
- Trial name
- NCT02469662
- Testing
- Nexel Total Elbow
- Where
- 11 sites in United States, Australia and 6 more
- Volunteers
- 134 people
- Sponsor
- Zimmer Biomet
Trauma, Patella Fracture
DePuy Synthes Variable Angle LCP Patella Plating System Study
The Depuy Synthes Locking Compression Plate (LCP) Variable Angle Patella Plating System is an FDA approved device. The purpose of this study is to see how well the Depuy Synthes LCP Variable Plating System work in fixing a broken…
- Conditions
- Trauma, Patella Fracture, Knee Cap, Knee Cap Injury
- Trial name
- NCT05824676
- Testing
- Variable Angle LCP Patella Plating System, Traditional Fixation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Hartford Hospital
Rib Fractures, Rib Fracture Multiple
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death.
- Conditions
- Rib Fractures, Rib Fracture Multiple, Rib; Fracture, With Flail Chest, Pain
- Trial name
- UNPIN (NCT05865327)
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Implantable Defibrillator User, Stress Reaction
Self-Management Interventions After an ICD Shock
This study, "Biobehavioral Intervention to Reduce PTSD Symptoms After an ICD Shock," addresses a critical need in cardiology care by describing the feasibility and acceptability of a timely, highly promising…
- Conditions
- Implantable Defibrillator User, Stress Reaction, Ptsd, Stress Management
- Trial name
- NCT06037785
- Testing
- Self-Paced Self-Management (SPSM)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
SPINAL Fracture, Burst Fracture
Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture
Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine.
- Conditions
- SPINAL Fracture, Burst Fracture, Spinal Instability of Thoracolumbar Region
- Trial name
- A34RCT (NCT05769114)
- Testing
- Surgical stabilization
- Where
- 2 sites in Switzerland
- Volunteers
- 52 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck
Z1 Hip System: Post-Market Clinical Follow Up Study
The objectives of this study are to confirm the early to mid- term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi- and primary total hip arthroplasty.
- Conditions
- Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
- Trial name
- NCT07104279
- Testing
- Z1 Femoral Hip System
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Tibial Shaft Fracture, Tibial Plateau Fracture
Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome
The purpose of this study is to evaluate both genotypic differences and differences in local gene expression in individuals who develop acute traumatic compartment syndrome relative to control patients with at-risk lower…
- Trial name
- NCT05521958
- Testing
- Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Spine Fracture, Orthosis
ORthosis vs No Orthosis After Surgically Treated Traumatic Thoracolumbar Fractures
Rationale: There is no evidence in the current literature regarding the additional value of an orthosis after surgically treated thoracolumbar spine fractures.
- Conditions
- Spine Fracture, Orthosis, Traumatic Fracture, Posterior Fixation
- Trial name
- ORNOT (NCT03097081)
- Testing
- No orthosis, Orthosis
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- Amsterdam UMC, location VUmc
Postoperative Cognitive Dysfunction, Orthopedic Procedures
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
This study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia.
- Conditions
- Postoperative Cognitive Dysfunction, Orthopedic Procedures, Postoperative Pain Management, Hip Fracture
- Trial name
- REMIND-ORTHO (NCT07113483)
- Testing
- Midazolam, REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO]
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Opioid Use, Fractures, Bone
Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures
An open reduction and internal fixation is a painful procedure requiring intensive postoperative pain management. Traditionally, opioid analgesia has been the gold standard for postoperative pain control.
- Conditions
- Opioid Use, Fractures, Bone, Trauma
- Trial name
- NCT06113211
- Testing
- Narcotic pain medication, Nonnarcotic pain medications
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Henry Ford Health System
Shoulder Arthritis, Shoulder Osteoarthritis
S-11 SMR TT Hybrid Glenoid and Cementless Finned Short Stem
Post-market, prospective, non randomized, open label, multicentre, clinical study analysing outcomes of shoulder arthroplasty with SMR TT Hybrid Glenoid with or without SMR Cementless Finned Short Stem
- Conditions
- Shoulder Arthritis, Shoulder Osteoarthritis, Arthrosis, Osteoarthritis
- Trial name
- NCT05314387
- Testing
- SMR TT Hybrid Glenoid without Cementless Finned Short Stem, SMR TT Hybrid Glenoid with Cementless Finned Short Stem
- Volunteers
- 100 people
- Sponsor
- Limacorporate S.p.a
Anterior Shoulder Dislocation, Shoulder Dislocation Closed Traumatic
Shoulder Dislocation: Assessment of Lesions, Trajectories and Outcomes (SALTO)
The goal of this prospective observational cohort study is to provide epidemiological and prognostic data from a defined urban population and to improve understanding of risk factors and long-term outcomes following first-time…
- Conditions
- Anterior Shoulder Dislocation, Shoulder Dislocation Closed Traumatic, First Time Shoulder Dislocation, Shoulder Instability
- Trial name
- SALTO (NCT07486440)
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Pelvic Fracture, Prostate Cancer
A COhort Study on Factors Leading to Vulnerability in Adult Patients With Serious Medical cOnditionS: the COSMOS-I Trial
The objective of this prospective multicentre study that recruits altogether 1500 older patients from the university hospitals of Tampere, Kuopio, and Oulu is to explore the clinical significance and detection of causes of…
- Conditions
- Pelvic Fracture, Prostate Cancer, Lung Cancer, Brain Metastasis
- Trial name
- COSMOS-I (NCT07740239)
- Testing
- Test set to determine vulnerability
- Where
- Finland
- Volunteers
- 2,050 people
- Sponsor
- Tampere University Hospital
Fractures, Bone
855303-RNA Biomarker Validation
The purpose of this study is to test the accuracy of using RNA in blood as a way to forecast new fracture healing outcome.
- Trial name
- 855303-RNAVal (NCT06872775)
- Testing
- Blood draws to assess RNA expression levels
- Where
- 7 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Pennsylvania
Arthroplasty, Replacement
SMR Stemless Reverse vs SMR Reverse Shoulder System
The SMR Stemless Reverse is intended for total, primary shoulder joint replacement by reducing pain and restoring shoulder articular mobility function.
- Trial name
- NCT04697004
- Testing
- Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- Limacorporate S.p.a
Pelvic Trauma, Pelvic Fracture
A Snapshot Audit of Traumatic Pelvic Ring Injuries
Multicenter, snapshot cohort studies or audits have the ability to gather large patient numbers in short time periods from many healthcare systems with different resources or practices of care concerning one specific surgical…
- Conditions
- Pelvic Trauma, Pelvic Fracture, Fragility Fractures of the Pelvis (FFP)
- Trial name
- NCT06540339
- Testing
- Snapshot-audit studies do not necessitate any intervention in the defined cohorts.
- Volunteers
- 500 people
- Sponsor
- University Hospital, Aachen
Sacral Fractures, Traumatic Unstable Sacral Fractures
Open Versus Minimally Invasive Fixation for Unstable Sacral Fractures in Adults
Severe injuries to the lower spine and pelvis, known as traumatic unstable sacral fractures, are complex injuries that often require surgery to stabilize the bones and prevent long-term disability.
- Conditions
- Sacral Fractures, Traumatic Unstable Sacral Fractures, Spinopelvic Dissociation, Pelvic Ring Injuries
- Trial name
- NCT07534579
- Volunteers
- 60 people
- Sponsor
- Assiut University
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Feasibility Study on Nitropaste Using Intraoperative SPY Imaging.
- Conditions
- Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
- Trial name
- SPY NITROPASTE (NCT07004764)
- Testing
- Nitroglycerin Ointment 2%
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University