Clinical trials: Traumatic Head Injury
Subarachnoid Hemorrhage, Intracerebral Hemorrhage
Multimodal Neuromonitoring
Theoretical Framework \& Background Cortical spreading depressions (CSD) and seizures, are crucial in the development of delayed cerebral ischemia and poor functional outcome in patients suffering from acute brain injuries such…
- Conditions
- Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Traumatic Brain Injury, Cortical Spreading Depolarization and Depression
- Trial name
- MMNM (NCT04737369)
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cerebral Hematoma, Traumatic, Intracerebral Hemorrhage, Traumatic
Interest of Real Time Measurement of Autonomous Nervous System for the Detection of Brain Death
Context: A major lack of organ donors is a serious public health problem. It determines a prolonged delay before a transplant can be performed and thus a significant number of deaths of patients waiting for transplantation.
- Conditions
- Cerebral Hematoma, Traumatic, Intracerebral Hemorrhage, Traumatic, Traumatic Brain Hemorrhage, Traumatic Brain Injury
- Trial name
- MEANS (NCT00918970)
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Traumatic Brain Injury
Intracranial Pressure (ICP) Monitoring Following Traumatic Brain Injury (TBI)
The aim of this retrospective cohort study is to evaluate complications rates, indications, and the utility of follow-up imaging studies of ICP measurement in severe TBI patients.
- Trial name
- NCT04428970
- Testing
- Invasive ICP monitoring
- Where
- Austria
- Volunteers
- 214 people
- Sponsor
- Medical University of Vienna
Traumatic Brain Injury
Pupillometry for the Prediction of Neurologic Outcomes in Severe Traumatic Brain Injury
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in the US. The CDC states that 1.7 million people sustain a traumatic brain injury each year, with death occurring in 52,000 of these injured patients.
- Trial name
- NCT02465242
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Our Lady of the Lake Hospital
Brain Concussion
Active Injury Management (AIM) After Pediatric Concussion
The proposed interventions of this study will determine the ideal discharge recommendations related to activity
- Trial name
- AIM (NCT03869970)
- Testing
- REST, ACTIVITY, mHEALTH
- Where
- 2 sites in United States
- Volunteers
- 237 people
- Sponsor
- Medical College of Wisconsin
Brain Concussion, Post-Concussion Syndrome
Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome
This study will evaluate the practicality (i.e. acceptability to stakeholders; outcome battery feasibility; recruitment, retention, and adherence rates) and the preliminary effect of a cognitive strategy training intervention in…
- Trial name
- NCT04681742
- Testing
- CO-OP Group
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Brain Injuries, Traumatic
Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial
This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to improve cognition and traumatic brain injury-related…
- Trial name
- NCT05632627
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Traumatic Brain Injury
Safety and Feasibility of Minocycline in the Treatment of Traumatic Brain Injury (TBI)
The purpose of this study is: 1. To assess the safety and feasibility of minocycline administration after TBI in a dose escalation study at two different doses over 7 days. 2.
- Trial name
- TBI (NCT01058395)
- Testing
- Minocycline
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Wayne State University
Acute Brain Injury, Traumatic Brain Injury
Connectivity and Neural Signatures of Consciousness in Unresponsive States
The CONSCIUS study is a prospective, interventional study including patients with acute brain injury and impaired consciousness implanted with intracranial electrodes.
- Conditions
- Acute Brain Injury, Traumatic Brain Injury, Consciousness Disorders, Seizures
- Trial name
- CONSCIUS (NCT06426615)
- Testing
- Intracranial electrodes
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Traumatic Brain Injury
Sodium Lactate in Severe TBI
This is a safety phase 2 clinical trial of intravenous infusion of sodium lactate in patients with severe TBI. This study is intended for patients in the acute setting in an intensive care unit at centers that have been selected…
- Trial name
- NCT06701760
- Testing
- Sodium Lactate
- Volunteers
- 264 people
- Sponsor
- University of California, Los Angeles
Brain Injury Traumatic Mild, Brain Injuries
Screening Emotions in Adolescents at the Hospital for mTBI
The goal of this observational study is to develop and validate a clinical tool to predict which adolescents aged 11 to less than 18 years of age with mild traumatic brain injury (mTBI) are at an increased risk for developing…
- Conditions
- Brain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial Hemorrhage
- Trial name
- SEARCH-mTBI (NCT06370520)
- Testing
- Validated Questionnaires, Questionnaires, Clinician / Medical Record Variables
- Where
- 6 sites in United States
- Volunteers
- 2,592 people
- Sponsor
- University of California, Davis
Trauma, Nervous System, Brain Trauma
Characterization of the Sleep-Wake Cycle in Traumatic Brain Injury Patients with a Disorder of Consciousness
Each year in France, 160,000 peoples suffer from a mild or severe traumatic brain injury (TBI). Sleep plays a crucial role in the process of brain plasticity, which is essential for neurological and cognitive recovery.
- Trial name
- SLEEPDOC (NCT06766513)
- Testing
- Actimetry, Subjective assessments, questionnaire
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
MTBI - Mild Traumatic Brain Injury
Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders
The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.
- Trial name
- NCT07282691
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Salus University
Concussion Injury of Cerebrum, Cranial Osteopathic Medicine
Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion
Patients who have concussions exhibit an array of symptoms, also known as post-concussive symptoms, including headaches, feeling slowed down or foggy and difficulty with concentration.
- Trial name
- NCT03225599
- Testing
- Cranial Osteopathic Manipulative Medicine
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Aplastic Anemia
Study of Fludarabine + Cyclophosphamide + TBI Conditioning Regimen for Double Units Cord Blood Transplantation(CBT)in Severe Aplastic Anemia(SAA)
Severe aplastic anemia is a fatal disease and patients without HLA matched siblings need alternative treatment option. Cord blood transplantation (CBT) has become an alternative treatment means in various diseases, but it has not…
- Trial name
- NCT00881933
- Testing
- Cyclophosphosphamide, TBI
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- The Korean Society of Pediatric Hematology Oncology
Patients in Minimally Conscious State After a Severe Brain Injury (e.g., Anoxia, Traumatic Brain Injury, Stroke)
tDCS in MCS: Repeated Stimulations
In this study researchers will apply transcranial direct current stimulation (tDCS) for 5 consecutive days in chronic patients in minimally conscious state (MCS).
- Trial name
- tDCS in MCS (NCT02019615)
- Testing
- transcranial direct current stimulation
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University of Liege
Traumatic Brain Injury
Evaluating the Effect of Tranexamic Acid on the Clinical Outcomes in Patients With Traumatic Brain Injury
Evaluate the effect of tranexamic acid on mortality in pediatric patients with traumatic brain injury. This could potentially lead to improved treatment protocols and better outcomes for this vulnerable population.
- Trial name
- NCT06330935
- Testing
- Tranexamic Acid (TXA), Normal saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Traumatic Brain Injury
Translational Research Examining Acupuncture Treatment in Traumatic Brain Injury
The purpose of this study is to examine the effects of acupuncture on cerebral blood flow (CBF) and blood biomarkers during the acute 10-day window following traumatic brain injury, to determine if those changes correlate with…
- Trial name
- TREAT-TBI (NCT02623218)
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- AOMA Graduate School of Integrative Medicine
Concussion, Brain
Neck Strengthening Program for the Prevention or Mitigation of Sports Concussion
Study looks to determine effectiveness of neck strengthening to reduce the incident, duration, and severity of sports related concussion in student athletes.
- Trial name
- PCONS (NCT03237468)
- Testing
- Neck strengthening exercise to prevent concussion
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- CentraCare
Rotator Cuff Tears, Rheumatoid Arthritis Shoulder
Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study
The goal of the Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study is to collect safety and performance data on the commercially available Shoulder iD™ Primary Reversed Glenoid device.
- Conditions
- Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus
- Trial name
- SiD (NCT05868148)
- Testing
- Shoulder iD™ Primary Reversed Glenoid
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stryker Trauma and Extremities
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.