Clinical trials: Traumatic Head Injury
Traumatic Brain Injury, Cerebral Stroke
Exoskeleton Rehabilitation on TBI
Background: Traumatic brain injury (TBI) is one of the leading causes of disability in the United States. The EKSO GT Bionics® (EKSO®) is a robotic exoskeleton approved by the Federal Drug Administration (FDA) for rehabilitation…
- Trial name
- Ekso-TBI (NCT04465019)
- Testing
- Exoskeleton Rehabilitation
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- DHR Health Institute for Research and Development
Traumatic Brain Injury
Development of Quality of Life Tool for TBI
Objectives: The ultimate goal of this research program is to promote seamless, comprehensive care for Operation Enduring Freedom/ Operation Iraqi Freedom (OEF/OIF) veterans.
- Trial name
- TBIQOL (NCT00714428)
- Where
- 4 sites in United States
- Volunteers
- 485 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Motor Vehicle Accidents, TBI (Traumatic Brain Injury)
Concussion in Motor Vehicle Accidents: The Concussion Identification Index
The primary goal of this study is to provide clinicians with a brief, patient self-administer instrument yielding a single composite score that reliably correlates with objective findings on standardized neurocognitive assessment…
- Conditions
- Motor Vehicle Accidents, TBI (Traumatic Brain Injury), Brain Contusion, Brain Injuries
- Trial name
- CIDI (NCT02858544)
- Testing
- The Concussion Identification Index, ImPACT
- Where
- United States
- Volunteers
- 1,790 people
- Sponsor
- Clionsky Neuro Systems Inc.
Subarachnoid Hemorrhage, Subdural Hematoma
Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury
The purpose of this study is to evaluate the antipyretic effect of bromocriptine in critically-ill patients with acute neurologic injury and fever from infectious and non-infectious etiologies.
- Conditions
- Subarachnoid Hemorrhage, Subdural Hematoma, Traumatic Brain Injury, Ischemic Stroke
- Trial name
- BFF (NCT03496545)
- Testing
- Bromocriptine 5 MG, Acetaminophen 650 MG
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of California, San Francisco
Hypothermia, Trauma
Meta-Analysis Accidental Hypothermia in Trauma
This is a systematic literature review and meta-analysis investigating the effect of accidental hypothermia on mortality in trauma patients overall and patients with TBI specifically.
- Conditions
- Hypothermia, Trauma, Brain Injuries, Traumatic, Morality
- Trial name
- NCT04332237
- Where
- Switzerland
- Volunteers
- 776,684 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Urinary Tract Infection, Head Injury
Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department
Patients seen in the ED with either a laceration, minor head injury, or urinary tract infection will be randomized to one of two groups.
- Conditions
- Urinary Tract Infection, Head Injury, Laceration
- Trial name
- NCT02882256
- Testing
- Video discharge instructions
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- George Washington University
Chronic Subdural Hematoma, Subdural Hematoma
Prospective Study on the Use of Middle Meningeal Artery Embolization for Chronic Subdural Haematoma
Subdural haematoma is a common neurosurgical condition that results in different levels of neurological deficits in patients. It can be further classified into acute and chronic, which have different pathophysiology.
- Trial name
- NCT04500795
- Testing
- Middle meningeal artery embolization
- Where
- China
- Sponsor
- Chinese University of Hong Kong
Traumatic Brain Injury
Single Photon Emission Computed Tomography (SPECT) Imaging Study of Professional American Football Players
The investigators primary objective is to acquire preliminary data on one-hundred former NFL veterans with at least one full year of professional service using brain SPECT imaging in order to assess the degree to which NFL…
- Trial name
- NCT01515839
- Testing
- Multivitamin Supplement intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amen Clinics, Inc.
Traumatic Brain Injury, Fatigue
Fatigue Following Moderate and Severe TBI
The subjective feeling of being periodically fatigued, tired, even exhausted is common in the general population, as well as in a large number of medical conditions, including neurological illness, such as traumatic brain injury…
- Trial name
- NCT03597763
- Where
- 2 sites in Norway
- Volunteers
- 104 people
- Sponsor
- University of Oslo
Traumatic Brain Injury, Posttraumatic Stress Disorders
Telepharmacy Robotic Medicine Delivery Unit "TRMDU" Assessment
The objective of this study is to evaluate whether use of TRMDU in addition to medication review leads to improved outcomes and reduced health care costs for patients when compared with medication review alone.
- Conditions
- Traumatic Brain Injury, Posttraumatic Stress Disorders, Trauma, Combat Disorders
- Trial name
- NCT01007006
- Testing
- TMRDU
- Where
- 3 sites in United States
- Sponsor
- University of Illinois Chicago
Traumatic Brain Injury
Improving Anticipatory and Compensatory Postural Responses to Avoid Falls After TBI
The purpose of this study is to assess a balance training program to see if it can be helpful to avoid falls in people who have had traumatic brain injuries (TBIs).
- Trial name
- NCT05268484
- Testing
- Perturbation-based Training with visual cues using Neurocom
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Concussion, Sports Injuries in Children
Cervico-vestibular Home Exercise Program Feasibility
The purpose of this pilot study is to: 1. Determine the feasibility of adherence to completing the home cervico-vestibular exercise program following concussion. 2.
- Trial name
- Concussion HEP (NCT07099248)
- Testing
- Cervico-vestibular Home Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy
Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the…
- Conditions
- Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
- Trial name
- NCT06665633
- Testing
- Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nova Southeastern University
Traumatic Brain Injury
The Predictive Value of Clinical and Immunological Factors in the Development of Pneumonia After Traumatic Brain Injury
The development of pneumonia and other infections is one of the most common complications of a traumatic brain injury (TBI). Prior studies have also found that patients suffering from TBI also develop immune dysfunction…
- Trial name
- NCT00929448
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Royal Alexandra Hospital
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Post-Concussion Symptoms, Insomnia
Neurotechnology Following Traumatic Brain Injury
This two-part study seeks to improve symptoms such as pain and sleep problems after concussion, or mild traumatic brain injury (mTBI).
- Conditions
- Post-Concussion Symptoms, Insomnia, Pain, Chronic, Depressive Symptoms
- Trial name
- Cereset (NCT03649958)
- Testing
- HIRREM-SOP or Cereset, Cereset 2x
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Brain State Technologies, LLC
Traumatic Brain Injury, Intracranial Hypertension
Optic Nerve Ultrasound in Severe Traumatic Injury
Prospective study of diagnostic accuracy of optic nerve sheath diameter measurement (index study) in traumatic brain injury with simultaneous invasive intracranial pressure monitoring as the reference standard.
- Trial name
- ONUS-TBI (NCT02618226)
- Testing
- Optic nerve ultrasound
- Where
- India
- Volunteers
- 117 people
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder
A Head-to-head Comparison of Virtual Reality Treatment for Post Traumatic Stress Disorder
Therapy that uses Virtual Reality (VR) has been shown to help in the treatment of Post Traumatic Stress Disorder (PTSD). It is unclear what role the VR simulator itself plays in recovery.
- Trial name
- NCT00978484
- Testing
- Virtual Reality Exposure Therapy - Dynamic, Augmented Exposure Therapy
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- United States Naval Medical Center, San Diego
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Motor Disorders, Healthy
Non-invasive BCI-controlled Assistive Devices
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery…
- Conditions
- Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases
- Trial name
- NCT05183152
- Testing
- NMES Feedback, Visual Feedback, TESS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
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