Clinical trials: Traumatic Injuries
Post Traumatic Stress Disorder
Early Prevention of Post Traumatic Stress Disorder
Sunnybrook Health Sciences Centre is Canada's largest trauma centre, treating 1,100 patients annually. A traumatic experience can lead to post-traumatic stress disorder, which increases hospital stays, emergency visits and…
- Trial name
- NCT02004743
- Testing
- Intervention, Treatment as usual
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Sunnybrook Health Sciences Centre
Neurologic Disorders, Nervous System Diseases
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will…
- Conditions
- Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders
- Trial name
- NEST (NCT02795052)
- Testing
- Intravenous and Intranasal BMSC
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Suicidal Ideation, Suicide, Attempted
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression
- Trial name
- ProjectGRRIT (NCT05401838)
- Testing
- Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of North Carolina, Charlotte
Traumatic Birth
Glucocorticoid Administration After Traumatic Birth
This study has two components, an observational and a trial component. The observational part is being done to screen for postpartum posttraumatic stress disorder by collecting mental health assessments in women who are…
- Trial name
- NCT04852458
- Testing
- Intravenous (IV) hydrocortisone
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder
Hair Cortisol Level as a Predictor of PTSD Development
Post-traumatic stress disorder, PTSD, is one of the most prevalent psychiatric disorders. As casualties of motor vehicle accidents, criminal acts or terrorism are arriving to the ER, it is almost impossible to conclude who will…
- Trial name
- NCT01804426
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Residual Limb Pain, Post-Traumatic Limb Pain
Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma
Combat-related extremity trauma frequently results in persistent pain, including neuropathic, residual limb, and phantom limb pain.
- Conditions
- Residual Limb Pain, Post-Traumatic Limb Pain, Extremity Trauma, Combat-Related Limb Injury
- Trial name
- KIN-LIMB (NCT07432685)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
PTSD, Alcohol Dependence
Couples-based Behavioral Psychotherapy for Male Patients With Posttraumatic Stress Disorder and Alcohol Dependence
Purpose: Phase I focus groups with clinicians and patients will gather qualitative data to focus and inform the content of Phase II.
- Trial name
- NCT00622921
- Testing
- Couples-based behavioral psychotherapy
- Where
- United States
- Sponsor
- Yale University
Traumatic Brain Injury, Mild Traumatic Brain Injury
Diagnosis of mTBI in a Community Setting
The purpose of this research study is to test whether a portable goggle system (I-PAS) is good at diagnosing mild traumatic brain injury (mTBI) in a community setting.
- Conditions
- Traumatic Brain Injury, Mild Traumatic Brain Injury, Brain Injuries, Brain Injuries, Traumatic
- Trial name
- NCT03539848
- Testing
- I-PAS Goggles
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Miami
Brain Concussion, Post-Concussion Syndrome
Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes
The purpose of this investigation is to determine the effect of a weighted compression vest in addition to usual medical care and exercise rehabilitation on cardiovascular, neurocognitive, balance and anxiety measures in…
- Trial name
- NCT02362347
- Testing
- London Health Sciences Centre - Compression Vest, exercise
- Where
- 2 sites in Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Functionally-Impaired Elderly, Caregivers
Impact on Family or Care-givers of Very Old ICU-survivors, Trajectories and 6 Months' Outcome in the Very Old.
It is known from extensive documentation that second victims in critical illness often are the care givers of the patients: family, friends or other persons.
- Conditions
- Functionally-Impaired Elderly, Caregivers, PTSD, Depression, Anxiety
- Trial name
- VIP2 (NCT03138278)
- Testing
- Telephone support on demand
- Sponsor
- University of Bergen
Blood Cancers, Leukemia
A Manualised Post-Traumatic Growth Intervention For People With Hematological Cancers In Greece
This clinical trial aims to determine whether a manualised group intervention for people with blood cancers can help them experience positive psychological changes following their diagnosis, known as post-traumatic growth.
- Conditions
- Blood Cancers, Leukemia, Lymphoma, Bone Marrow Transplant
- Trial name
- NCT07814170
- Testing
- A manualised post-traumatic growth intervention for people with hematological cancers
- Where
- 2 sites in Greece
- Volunteers
- 80 people
- Sponsor
- University of West Attica
PTSD
Service Dogs for Veterans With PTSD
The purpose of this study is to evaluate use of service dogs for individuals who have been diagnosed with Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01329341
- Testing
- Service Dogs
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Trauma, Posttraumatic Stress Disorder
Stress-induced Drinking in Emerging Adults: the Role of Trauma History
This project is the first to use a clinical laboratory method in emerging adults to test the hypothesis that a trauma history with or without concommitant posttraumatic stress disorder (PTSD) alters response to a stressor and…
- Trial name
- ARC5 (NCT01363180)
- Testing
- Trier Social Stress Test (TSST), No stress condition
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Mild Traumatic Brain Injury
Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBI
Veterans with mild traumatic brain injury continue to deal with symptoms that interfere with their ability to engage in productive activities.
- Trial name
- NCT04044456
- Testing
- Goal Management Training, Attention Training, Brain Health Workshop
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Cognitive Training for PTSD
Posttraumatic stress disorder (PTSD) is a chronic, disabling condition that occurs in a subgroup of individuals after experiencing traumatic stress, and is common in Veterans seeking mental health treatment at the VA.
- Trial name
- NCT03316196
- Testing
- COGENT COGNITIVE TRAINING, Non training computer condition
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Heart Rate Variability
Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness
The purpose of this randomized controlled trial was to compare the effectiveness of an HRV-BF intervention versus a health promotion active control intervention focused on improving mental health symptoms among people…
- Trial name
- HRV-BF (NCT05897580)
- Testing
- Heart Rate Variability - Biofeedback (HRV-BF), Health Promotion (HP)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Neuralgia
P4 (Pregabalin for Peripheral Posttraumatic Pain)
To evaluate the efficacy of pregabalin compared to placebo in the treatment of posttraumatic peripheral neuropathic pain
- Trial name
- P4 (NCT00292188)
- Testing
- pregabalin
- Where
- 44 sites in Belgium, Canada and 9 more
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Epilepsy, Seizure Disorder
Epilepsy Learning Healthcare System (ELHS)
The Epilepsy Learning Health System (ELHS) is a quality improvement and research network to improve outcomes for people with epilepsy.
- Conditions
- Epilepsy, Seizure Disorder, Neurologic Disorder, Rare Diseases
- Trial name
- ELHS (NCT06265103)
- Testing
- Clinical care and quality improvement
- Where
- 13 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Epilepsy Foundation of America
Post-traumatic Stress Disorder (PTSD), Postpartum Mental Health
A Computer Game for Postpartum Mental Health After Emergency Cesarean Birth
This study aims to explore whether playing the computer game Tetris can reduce PTSD symptoms in women who have undergone emergency caesarean births.
- Trial name
- NCT07290127
- Testing
- implementation of a brief computer-based intervention "Tetris"
- Where
- Japan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyoto University, Graduate School of Medicine
Post Traumatic Stress Symptoms, PTSD
Nonattachment Training for Post Traumatic Stress Recovery
This pilot study aims to investigate the effectiveness of a novel, co-created intervention based on principles of nonattachment for individuals recovering from Post-Traumatic Stress (PTS). Objectives include: 1.
- Trial name
- NPTS (NCT06683027)
- Testing
- Nonattachment for Post Traumatic Stress
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Derby
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