Clinical trials: Traumatic Injuries
Trauma, Shock, Traumatic
Comparison of Ketamine and Etomidate During Rapid Sequence Intubation in Trauma Patients
In trauma patients with high shock index, the investigators compare the effects on hemodynamics between ketamine and etomidate.
- Trial name
- NCT04120870
- Testing
- Etomidate Injection 0.2 mg/kg, Ketamine injection 2 mg/kg
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Ajou University School of Medicine
Long Term Adverse Effects, Combat Disorders
Long-term Health Outcomes of AE Casualties
This study involves individuals who are currently participating in the Wounded Warrior Recovery Project and underwent aeromedical evacuation (AE) due to injury during deployment in Iraq or Afghanistan.
- Trial name
- NCT03736356
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Ian Stewart
Stress Disorders, Post-Traumatic
Comparing Effects of a Holistic Yoga Program and a Wellness Program on PTSD Symptoms
Given the limited effectiveness of current treatments and the burden PTSD places on Veterans, civilians and clinicians, this research aims to compare the effects of a standardized, traditional, holistic yoga intervention…
- Trial name
- RELIEVE (NCT02234622)
- Testing
- Holistic Yoga Program, Wellness Lifestyle Program
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- VA Office of Research and Development
Opioid-use Disorder, Addiction
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Trial name
- CLARO (NCT04559893)
- Testing
- Collaborative Care
- Where
- 16 sites in United States
- Volunteers
- 729 people
- Sponsor
- RAND
Post Traumatic Stress Disorder
eTMS for Veterans and First Responders With PTSD
A battery of physiological and behavioral data will be collected before and after application of eTMS. Participants will be veterans or first responders diagnosed with PTSD.
- Trial name
- NCT06294106
- Testing
- Electroencephalogram personalized Transcranial Magnetic Stimulation (eTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Polytechnic Institute and State University
Traumatic Brain Injury
Could Early Atorvastatin Offer Anti Inflammatory Effects Upon Brain in Traumatic Head Injury?
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, known as statins, are widely used to reduce levels of low-density lipoprotein-cholesterol.
- Trial name
- NCT04718155
- Testing
- Atorvastatin
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pain, Pain Syndrome
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071949
- Testing
- Adezunap
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Insomnia, Post Traumatic Stress Disorder
Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-CBTi Study)
The COVID-19 pandemic has resulted in increased workload and concerns about personal and family safety for frontline healthcare workers (HCWs), which can lead to decreased well-being and worsening mental health.
- Conditions
- Insomnia, Post Traumatic Stress Disorder, Anxiety Disorders, Depression
- Trial name
- HCW-CBTi (NCT05816304)
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia (dCBTi)
- Where
- 2 sites in Canada
- Volunteers
- 366 people
- Sponsor
- University Health Network, Toronto
Brain Injuries, Traumatic, Executive Dysfunction
GOALS Cognitive Training Delivered to Aging Veterans in Person or Via Telehealth
This study will use technology to deliver effective treatment for cognitive problems associated with TBI to Veterans at home, which may result in improved daily functioning and increased access to health care for the growing…
- Trial name
- TeleGOALS (NCT04111549)
- Testing
- Home-based telehealth GOALS, In-person GOALS
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Inflammatory Response
Dexamethasone in Traumatic Brain Injury
In this study, our aim is to investigate the role of Dexamethasone for modulating the inflammation in patients with traumatic brain injury (TBI).
- Trial name
- NCT05323149
- Testing
- Saline, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Traumatic Brain Injury, Trauma
The Neuromarker S-100B in Patients With Different Types of Intracranial Injury
Abstract: The most widely studied neuro-markers in traumatic brain injury (TBI) are S100B and neurone specific enolase (NSE). S-100B is localized in astroglia.
- Trial name
- NCT01619293
- Where
- Austria
- Volunteers
- 1,800 people
- Sponsor
- Medical University of Vienna
Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Bursa Augmentation in Arthroscopic Rotator Cuff Repair
The aim of this first study is to investigate in a case series through sequential sonographic imaging, using Doppler ultrasonography, the postoperative morphology, especially vascularity and findings of neovascularity, after…
- Trial name
- ARCR-Bursa (NCT03986749)
- Testing
- Doppler ultrasonography after bursa augmentation
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Schulthess Klinik
Pregnant Women, Prenatal Yoga
Prenatal Yoga Intervention in Pregnant Women
The aim of this study is to determine the effects of a prenatal yoga intervention on traumatic childbirth perception, self-perception, and delivery preferences in pregnant women.
- Conditions
- Pregnant Women, Prenatal Yoga, Trauma, Body Image
- Trial name
- NCT07585916
- Testing
- Prenatal Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees
The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT06194838
- Testing
- Ossur Power Knee, Reboocon Intuy Knee
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Liberating Technologies, Inc.
Post-Traumatic Stress Disorders, Anxiety
fMRI in Posttraumatic Stress Disorder (PTSD) During Working Memory Updating
Neuropsychological studies investigating trauma-exposed and posttraumatic stress disorder (PTSD) subjects have generally underlined the significantly poorer performance of tasks that require attention, concentration, and verbal…
- Conditions
- Post-Traumatic Stress Disorders, Anxiety, Amnesia, Dissociative
- Trial name
- METRAPI (NCT00288314)
- Testing
- Magnetic Resonance Imaging, Functional
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Posttraumatic Stress Disorder
A Pilot Exercise Study for PTSD in Women Veterans
The overall aim of this pilot feasibility study is to determine if 12-week moderate intensity exercise can safely alleviate posttraumatic symptoms in premenopausal women veterans. Specific aims of the study are to; 1.
- Trial name
- NCT01892033
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- North Texas Veterans Healthcare System
Traumatic Brain Injury, Intracranial Hypertension
Comparison of 2 Doses of Mannitol on Post Traumatic Intracranial Hypertension and Cerebral Monitoring
Will an increase of the dose of mannitol improve the effects on neuromonitoring in patients suffering intracranial hypertension following traumatic brain injury?
- Trial name
- NCT00795587
- Testing
- variation of mannitol dose
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Grenoble
Post-Traumatic Stress Disorder
Treating People With Post-Traumatic Stress Disorder With Cognitive Behavioral Therapy for Insomnia
This study will test the effectiveness of cognitive behavioral therapy for insomnia in treating sleep disturbances in people with post-traumatic stress disorder.
- Trial name
- NCT00881647
- Testing
- Cognitive Behavioral Treatment for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder
Efficacy of Internet-delivered Trauma-focused CBT for Young People With PTSD
The goal of this clinical trial is to compare therapist-guided internet delivered trauma-focused cognitive behavior therapy (CBT) to an active control condition comprising therapist-guided internet delivered cognitive behavioral…
- Trial name
- NCT06185244
- Testing
- Therapist-supported internet-delivered trauma-focused CBT, 12 weeks of therapist-supported internet-delivered psychoeducation and stress management/relaxation for both the youth and the care giver.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska Institutet
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.