Clinical trials: Traumatic Injuries
Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders
Body Therapy for War Veterans With Post Traumatic Stress Disorder (PTSD)
The present study is a randomized, controlled trial that compares a certain type of body therapy, called ManuVision, to treatment as usual (TAU) in war veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders, Behavioral Symptoms, Depression
- Trial name
- NCT03777800
- Testing
- Body therapy, Treatment as usual
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Southern Denmark
Traumatic Brain Injury (TBI), Agitated Behaviour
Modified Environment for Agitation in Patients With TBI
This study examines the effect of an intervention consisting of dynamic circadian light and sound therapy, as well as systematic information on sleep pattern, agitated behavior and functioning level.
- Trial name
- ABS (NCT02524067)
- Testing
- Multifactorial circadian concept
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Traumatic Brain Injury, Alzheimer Disease
The Aging Brain ANSWERS Program
This study will test the effectiveness of an intervention for Veterans diagnosed with Alzheimer's Disease (AD) or Traumatic Brain Injury (TBI) and the burden on their informal (family/friend) caregiver.
- Conditions
- Traumatic Brain Injury, Alzheimer Disease, Veterans, Family Caregivers
- Trial name
- ABC ANSWERS (NCT03397667)
- Testing
- ABC ANSWERS, Control
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Indiana University
PTSD
To Test the Potential Efficacy of Repeated Intranasal Administration of Ketamine as a Treatment for PTSD
The purpose of this study is to see whether ketamine, when given repeatedly via the nose (intranasally), can produce a quick and persistent improvement in PTSD symptoms.
- Trial name
- NCT02398136
- Testing
- Ketamine, Midazolam
- Sponsor
- Adriana Feder
Depression, Mild Traumatic Brain Injury
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans…
- Conditions
- Depression, Mild Traumatic Brain Injury, Concussion, Brain
- Trial name
- NCT05682677
- Testing
- iTBS, Personalized, Augmented Cognitive Training (PACT)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, San Diego
Traumatic Brain Injury
Improving Time-Based Prospective Memory in TBI
This research aims to test aspects of a computer-based cognitive rehabilitation program designed to improve thinking skills in individuals with traumatic brain injury (TBI).
- Trial name
- TBPM (NCT04065477)
- Testing
- computer-based cognitive rehabilitation (CBCR)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Kessler Foundation
Post Traumatic Stress Disorder, Alcohol Use Disorder
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder
The study investigators are conducting the first randomized placebo-controlled trial of MDMA-assisted therapy with a comorbid sample of military Veterans with a co-occurring diagnosis of Alcohol Use Disorder (AUD) and…
- Trial name
- MAP VETS (NCT07118839)
- Testing
- Full Dose MDMA, MDMA-Assisted psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury
Integrated Eye Tracking and Neural Monitoring for Enhanced Assessment of Mild TBI: Primary Study
This study was conducted to develop and validate integrated eye tracking and EEG measures for assessment of mild traumatic brain injury.
- Trial name
- NCT03777228
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Head Injury, Traumatic Brain Injury
Outcomes of Early Versus Late Tracheostomy in Critically Ill Patients Due to Head Injury: A Randomized Controlled Trial
Tracheostomy is a surgical procedure that involves creating an opening in the trachea and bringing it to the skin surface to form a stoma. It may be performed as an emergency or elective operation.
- Trial name
- NCT07872865
- Testing
- Tracheostomy
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- University Of Anbar
Traumatic Brain Injury, Coping Skills
Telemedicine Brain Injury Coping Skills (BICS-T) Support Group for Brain Injury Survivors and Their Caregivers
Brain Injury can be devastating for both patients and family members and can result in chronic difficulties in vocational, social, financial, as well as physical functioning.
- Trial name
- BICS-T I (NCT04371211)
- Testing
- Telemedicine Brain Injury Coping Skills
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Rehabilitation Hospital of Indiana
PTSD, Adolescent
Neural Connectivity During Therapy for Adolescent PTSD
Posttraumatic stress disorder in adolescence impairs neurobiological networks underlying cognitive, social and emotional skills.
- Conditions
- PTSD, Adolescent, Psychological Trauma
- Trial name
- NCT05423444
- Testing
- TF-CBT, TAU
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Head Injury Trauma, Cognition Disorder
Assessment and Rehabilitation of Social Cognition in People With Traumatic Brain Injury
Patients who have suffered moderate to severe traumatic brain injury (TBI) frequently develop behavioural changes, which can have deleterious consequences on interpersonal relationships, social, family and professional…
- Trial name
- CogniSo-TC (NCT04562844)
- Testing
- sociale cognition
- Where
- 4 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Stress, Work Related Stress
Emergency Medical Staff Workload Analysis
The aim of this study is to identify trauma determinants and leverage this understanding to develop solutions applicable to the prevention and treatment of PTSD among emergency medical personnel.
- Conditions
- Stress, Work Related Stress, PTSD, Mental Stress
- Trial name
- NCT06302764
- Testing
- Qualitative & Quantitative Research
- Where
- 3 sites in Poland, Portugal and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
PTSD, Chronic Pain
iACT for PTSD and Chronic Pain : a Development Pilot Series
The primary aim of this study is to investigate the effect of Internet-delivered Acceptance and commitment therapy for PTSD and comorbid chronic pain.
- Trial name
- NCT04306809
- Testing
- Internet-delivered ACT for PTSD and chronic pain
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Skane University Hospital
Quality of Life, Post ICU Discharge
Study in Intensive Care Follow-up Programme in Improving Long-term Outcomes of ICU Survivors
Study Hypothesis: Critical illness is associated with long-term medical and psychological sequelae that can impact the professional and private life.
- Trial name
- SUIVI-REA (NCT01796509)
- Testing
- Medical, psychological, social
- Where
- France
- Volunteers
- 545 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain Injury
Genotype Influence on Recovery After Traumatic Brain Injury
Genetic differences in response to brain injury may reasonably be expected to play a role in the initial consequences of traumatic brain injury and in the rate of recovery from such injury.
- Trial name
- NCT00018499
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Traumatic Brain Injury
Rehabilitation of Traumatic Brain Injury in Active Duty Military Personnel and Veterans
Context: Traumatic brain injury (TBI) is a common condition associated with significant long-term cognitive, behavioral, and functional morbidities.
- Trial name
- NCT00540020
- Testing
- Rehabilitation
- Volunteers
- 360 people
- Sponsor
- The Defense and Veterans Brain Injury Center
Concussion
ImPACT Version 4-Touchscreen: Normative and Reliability Study
This research study is designed to establish normative database and reliability of ImPACT for adolescents and adults ages 12 through 80 to expand the use of devices to include touchscreen.
- Trial name
- NCT05551520
- Testing
- Normative, Reliability
- Where
- United States
- Volunteers
- 1,437 people, healthy volunteers welcome
- Sponsor
- ImPACT Applications, Inc.
Injuries
Incidence of Acute Injuries in Boxing
A prospective cohort study with 9 months follow up was carried out in 2017-2018. Boxers of both sexes 18 years and older from all 7 boxing clubs in Iceland were invited to participate in the study.
- Trial name
- NCT06264323
- Where
- Iceland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Injury Traumatic, Pain, Acute
Safety and Efficacy of Sufentanil Administration by Paramedics in Acute Trauma
The safety and efficacy of competence of paramedics to administer sufentanil intravenously in adult acute trauma patients without presence or without phone-call consult with an emergency medical doctor will be assessed in this…
- Trial name
- NCT06514469
- Testing
- Sufentanil intravenous administration followed consultation of remote physician, Sufentanil intravenous administration based on paramedic competency
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Zdravotnicka Zachranna Sluzba Karlovarskeho Kraje, P.O.
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