Clinical trials: Traumatic Injuries
Post-Traumatic Stress Disorders
Treatment of NLP Method in Women Who Have Experienced Postpartum Post Traumatic Stress Dissorder
The purpose of this interventional study is to evaluate the effectiveness of the NLP PTSD protocol in the event of PPPTSD. The study's main hypothesis is that the implementation of the NLP protocol will be effective and result in…
- Trial name
- NLP (NCT02730806)
- Testing
- NLP
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yfat Weinstein-Zohar
Leg Injuries, Trauma
PRIORITI-MTF Study- Testing Patient Response to the IDEO
The goal of the PRIORITI-MTF study is to help determine whether a new type of custom designed brace, called the IDEO ™ along with a physical therapy program, called Return to Run, improves physical function.
- Trial name
- PRIORITI-MTF (NCT02158884)
- Testing
- IDEO brace
- Where
- 3 sites in United States
- Volunteers
- 91 people
- Sponsor
- Major Extremity Trauma Research Consortium
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Post Traumatic Stress Disorder
A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD)
This study is designed to provide information on whether the drug MDMA, combined with Cognitive Processing Therapy (CPT), is safe and helpful for people with Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT05067244
- Testing
- MDMA
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Remedy
Traumatic Brain Injury
Personalized Cognitive Integrated Motor Training Using Virtual Reality to Improve Gait and Balance
Problems with walking and balance are common after traumatic brain injury (TBI). Walking and balance problems limit independence and increase risk for injuries due to falls.
- Trial name
- CMT (NCT06473987)
- Testing
- Personalized cognitive-sensorimotor VR/AR training, Traditional dual-task training, Standard of Care
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Kessler Foundation
Osteoarthritis (OA) of the Hip, Avascular Necrosis of Bone of Hip
MDR Vivacit-E Elevated Study
The main objective of this study is to confirm long-term safety, performance, and clinical benefits of the Vivacit-E Vitamin E HXLPE Elevated Liners when used in primary total hip arthroplasty.
- Conditions
- Osteoarthritis (OA) of the Hip, Avascular Necrosis of Bone of Hip, Protrusio Acetabuli, Traumatic Arthropathy-Hip
- Trial name
- NCT07150221
- Testing
- Vivacit-E Elevated Liners
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Zimmer Biomet
PTSD
Peer Enhanced Prolonged Exposure
The investigators plan to develop and test an intervention using peer specialists (Veterans who have managed PTSD and completed PE) to provide support services for Veterans using prolonged exposure therapy.
- Trial name
- PEET (NCT02818114)
- Testing
- Peer Enhanced Prolonged Exposure
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- VA Office of Research and Development
Stress Disorder, Post-traumatic
Sensory Stimulation Program Delivered by Family Members of Brain-injured Patients in Critical Care: Effect on Relatives' Post-traumatic Stress
Severe traumatic brain injuries are common and can lead to major long-term disability. Patients with severe brain injury often require admission to critical care.
- Trial name
- StimulSensRea (NCT07456384)
- Testing
- Standardized family-delivered neurosensory stimulation protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims
Bereavement, Prolonged Grief Disorder
Cognitive Behavioural Therapy for Complicated Grief Reactions in Old Age
While most bereaved individuals cope adaptively with the loss of a loved one, a significant minority experiences more severe and complicated grief reactions.
- Conditions
- Bereavement, Prolonged Grief Disorder, Depression, Anxiety
- Trial name
- NCT04694807
- Testing
- Group-based Cognitive Behavioural Therapy for Complicated Grief Reactions, Individually delivered Cognitive Behavioural Therapy for Complicated Grief Reactions
- Where
- Denmark
- Volunteers
- 113 people
- Sponsor
- University of Aarhus
Posttraumatic Stress Disorder
Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder
This study will examine MDMA-assisted psychotherapy in individuals aged 18 years or older diagnosed with PTSD, with PTSD symptoms not improving after trying at least one treatment.
- Trial name
- NCT00353938
- Testing
- 3,4-methylenedioxymethamphetamine (125 mg), 3,4-methyelendioxymethamphetamine (25 mg), Therapy
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Resilient Pharmaceuticals
Traumatic Brain Injury, PTSD
Structural and Functional Neuroimaging Studies of Combat Veterans
Background: Studies have shown that some people develop post-traumatic stress disorder (PTSD) after being exposed to the trauma of military combat.
- Trial name
- NCT01296126
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Brain Injury (TBI) Patients, Intracerebral Hemorrhage
Smartphone Enabled Detection of Cognitive Motor Dissociation in the ICU
The purpose of this research study is to evaluate whether a smartphone-enabled EEG (electroencephalography) system can be used to detect Cognitive Motor Dissociation (CMD) in patients with acute neurological injuries who appear…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Cardiac Arrest (CA)
- Trial name
- SMART-CMD (NCT07917728)
- Where
- 9 sites in United States, Brazil and 3 more
- Volunteers
- 240 people
- Sponsor
- Columbia University
Multiple Trauma, Pain, Acute
Intranasal Ketamine Versus Intranasal Fentanyl
Abstract Background: Given the inadequate control of pain in patients with injury that refer to the emergency departments, the rapid onset of action of intranasal administration in pain management, and the avoidance of…
- Trial name
- NCT04414800
- Testing
- Ketamine, Fentanyl
- Where
- Iran
- Volunteers
- 125 people
- Sponsor
- Isfahan University of Medical Sciences
Venous Thromboembolism, Pulmonary Embolus
Multicenter Registry for Comparative Effectiveness Analysis of Venous Thromboembolism in Trauma Patients
Venous thromboembolism (VTE) remains a leading cause of death in trauma patients. Based on the EAST Management Guidelines for the prevention of VTE in trauma patients, a number of research questions could be addressed by a…
- Conditions
- Venous Thromboembolism, Pulmonary Embolus, Deep Vein Thrombosis
- Trial name
- CLOTT (NCT01890044)
- Where
- United States
- Sponsor
- Scripps Health
Traumatic Brain Injury, Multiple Sclerosis
Measuring Cerebral Blood Flow Using Pseudo-continuous Arterial Spin Labeling Perfusion Magnetic Resonance Imaging
This study will test a new MRI sequence that measures cerebral blood flow (CBF). Because this technique for measuring CBF is new, there is little information on what the normal values for different regions of the brain should be.
- Conditions
- Traumatic Brain Injury, Multiple Sclerosis, Alzheimer's Disease, Tumor
- Trial name
- NCT02767609
- Testing
- Magnetic Resonance Imaging
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Stress Disorders, Post-Traumatic
Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Hyperarousal is a key symptom of PTSD. Even after receiving trauma-focused therapy, PTSD patients may continue to suffer from hyperarousal.
- Trial name
- BaRT (NCT00855816)
- Testing
- Breathing training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Alcoholism, Alcohol Dependence
The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD
Objective: Alcoholism is highly co-morbid with post traumatic stress disorder (PTSD). Since stress and negative affective states are major relapse triggering factors for alcohol use, the negative symptoms associated with PTSD are…
- Conditions
- Alcoholism, Alcohol Dependence, Posttraumatic Stress Disorder
- Trial name
- NCT00896038
- Testing
- Aprepitant
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Visual Field Defect, Stroke
Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual…
- Conditions
- Visual Field Defect, Stroke, Hemianopia, Quadrantanopia
- Trial name
- VIBRANT (NCT07105358)
- Testing
- transcranial random noise stimulation (tRNS), Perceptual learning-based training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgetown University
Traumatic Brain Injury
Integrated Eye Tracking and Neural Monitoring for TBI: Optimization
Traumatic brain injury (TBI) is one of the most frequent injuries affecting service members. Unfortunately, current neurocognitive assessment tools are unable to reliably detect mild TBI more than a few days post- injury.
- Trial name
- NCT03451058
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
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