Clinical trials: Traumatic Injuries
Stress Disorders, Post-Traumatic, HIV Infections
Efficacy of Group Intervention to Reduce Stress Symptoms
This research study will examine the usefulness of groups in reducing stress and helping individuals with HIV to stay healthy and avoid problems associated with sexually transmitted diseases.
- Trial name
- NCT00611338
- Testing
- HIV Skills-based Prevention
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Stanford University
Acute Pain, Wound Care
RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain
The Ketamine for Acute Pain in Burns study is a randomized, double-blind, parallel group trial (RCT) with active control (usual care) contrasting the efficacy and safety of "Ketamine Plus Opiate-based usual care" (O+K) with the…
- Conditions
- Acute Pain, Wound Care, Posttraumatic Stress Disorder
- Trial name
- NCT03305055
- Testing
- ketamine, Fentanyl
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder
Empowering Perinatal Adolescents Through Writing
This is a feasibility and acceptability study of Written Exposure Therapy (WET) for PTSD in pregnant and postpartum adolescents and youth with PTSD.
- Conditions
- Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
- Trial name
- EMPWR (NCT06771817)
- Testing
- Written Exposure Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Texas Southwestern Medical Center
Posttraumatic Stress Disorder (PTSD)
Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) for Treatment of Post-Traumatic Stress Disorder (PTSD)
This study is testing a personalized form of brain stimulation called PrTMS as a treatment for post-traumatic stress disorder (PTSD) in military service members and veterans.
- Trial name
- NCT07526285
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Pinprick Sensation Diminished, Amputation, Traumatic
Evaluation of Result and Influence Factors on Composite Graft in Fingertip Amputation
Fingertips facilitate smooth motor activity, precise sensation, and the delicate movement of the hands and have an aesthetic function.
- Conditions
- Pinprick Sensation Diminished, Amputation, Traumatic, Pain
- Trial name
- NCT02419885
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Posttraumatic Stress Disorder (PTSD)
Non Invasive Brain Stimulation for PTSD
This study is designed to identify changes in the brain that underlie symptoms of combat-related PTSD using brain imaging (fMRI).
- Trial name
- NCT02442843
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Traumatic Shock
AVERT Shock: Arginine Vasopressin During the Early Resuscitation of Traumatic Shock
Trauma patients, who are transfused with multiple blood products to treat shock due to blood loss, frequently develop inappropriately low vasopressin levels.
- Trial name
- AVERTShock (NCT01611935)
- Testing
- Vasopressin
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Pennsylvania
Stroke, Traumatic Brain Injury
Validation of the FOUR Coma Scale in Russia.
The purpose of this study is to examine the validity of the Russian version of the FOUR Full Outline of UnResponsiveness (hereafter FOUR) scale in adult ICU patients with an acute cerebral insufficiency clinic (hereinafter…
- Conditions
- Stroke, Traumatic Brain Injury, Subarachnoid Hemorrhage
- Trial name
- FOUR-RUS (NCT04018989)
- Where
- 3 sites in Russia
- Volunteers
- 260 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Stress Disorders, Post-Traumatic
The Effects of Home-Based Telemental Health for Rural Veterans With PTSD
The intent of this study is to assess whether cognitive functioning improves as Post-Traumatic Stress Disorder (PTSD) symptoms decrease as a step toward developing an objective measure of PTSD improvement.
- Trial name
- HBTMH (NCT02295410)
- Testing
- CPT
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Pacific Islands Health Care System
Normal Physiology, fMRI
The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans
Background: Two areas on the surface of the brain, the dorsolateral prefrontal cortex (DLPFC) and motor cortex (MC), play a key role during learning.
- Trial name
- NCT01260740
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Brain Injury, Intracranial Hypertension
Effect of Ketamine (Ketalar) on Intracranial Pressure
Objectives: Ketamine is an effective, short-acting anesthetic drug, which does not decrease blood pressure. It is widely stated that Ketamine increases intracranial pressure (ICP), which prevents its use in many emergency…
- Trial name
- NCT00437814
- Testing
- Ketamine, effect on intracranial pressure
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Post-Traumatic Stress Disorder, Mental Disorders
The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women
This study will determine the effectiveness of the Trauma Recovery and Empowerment Model in reducing the severity of post-traumatic stress disorder symptoms in women with mental disorders and who have experienced sexual or…
- Conditions
- Post-Traumatic Stress Disorder, Mental Disorders, Depression
- Trial name
- TREM (NCT00183716)
- Testing
- Trauma Recovery and Empowerment Model (TREM), Usual care
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Traumatic Brain Injury
Functional Near-Infrared Spectroscopy (fNIRS) Assessing Neural Activity During Virtual Reality Walking Intervention
The purpose of this study is to evaluate the safety and feasibility of using a portable neuroimaging device called functional near-infrared spectroscopy (fNIRS) to successfully analyze fNIRS data in individuals with chronic TBI…
- Trial name
- fNIRS (NCT06276894)
- Testing
- Motek C-Mill™ treadmill, training session with and without VR wearing the fNIRS cap
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Craig Hospital
Traumatic Brain Injury
Aerobic Exercise After Traumatic Brain Injury
The purpose of this study is to examine the effects of individualized aerobic exercise regimen on recovery after traumatic brain injury (TBI).Investigators will determine if exercise facilitates recovery by facilitating…
- Trial name
- AER-TBI1 (NCT05786729)
- Testing
- Aerobic Exercise (AER), Rehabilitation
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Centre for Neuro Skills
Trauma, PTSD
Posttraumatic Stress Symptoms Among Rescuers at Risk
This cross-sectional, anonymous online survey aims to examine how salient variables influence PTSS, well-being, and suicidal ideation across the following professions of rescue workers: firefighters, ambulance personnel, police…
- Conditions
- Trauma, PTSD, Self Efficacy, Coping Skills
- Trial name
- NCT03842553
- Testing
- No Intervention: anonymous online survey
- Where
- Switzerland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- University of Bern
Posttraumatic Stress Disorder With Attention Defic
Atomoxetine and Executive Function in PTSD
Attention deficits (AD) frequently co-occur with posttraumatic stress disorder (PTSD). The presence of AD is associated with greater PTSD clinical severity and poorer clinical outcomes.
- Trial name
- NCT06573970
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric Patients
This study will evaluate the administration of N-Acetyl-cysteine in combination with multi-vitamins/minerals in geriatric population (>60 years of age) who have experienced a traumatic brain injury.
- Trial name
- NCT04291066
- Testing
- N-Acetyl cysteine
- Where
- 2 sites in United States
- Volunteers
- 92 people
- Sponsor
- HonorHealth Research Institute
Intracranial Hemorrhage, Traumatic, Embolism and Thrombosis
Traumatic Intracranial Hemorrhage in Users of Oral Antithrombotic Drugs
Oral antithrombotic medications (OAM) are used for the prevention and treatment of thrombotic disorders. Among hemorrhagic complications of OAMs, intracranial hemorrhage (ICH) may have particularly devastating consequences with…
- Conditions
- Intracranial Hemorrhage, Traumatic, Embolism and Thrombosis, Hematoma, Subdural, Intracranial
- Trial name
- NCT02996851
- Volunteers
- 6,279 people
- Sponsor
- St. Olavs Hospital
PTSD, Alcohol Use Disorder
Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems
The investigators propose to conduct a clinical trial to evaluate sertraline treatment efficacy in a large sample of military veterans with a dual diagnosis of PTSD and Alcohol Use Disorder who are receiving Cognitive and…
- Trial name
- DDx (NCT02504931)
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Concussion, Professional TOP14 Rugby Players
Blood Biomarkers for the Management of Concussion in Professional Rugby Players
In the past 20 years, the incidence of concussion in direct contact sports has significantly increased. The incidence of concussion in rugby players ranges between 8 to 17 episodes / 1000 playing hours.
- Trial name
- RUGBYPROS100B (NCT02930395)
- Testing
- serum S100B assay
- Where
- France
- Volunteers
- 560 people
- Sponsor
- University Hospital, Clermont-Ferrand
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