Clinical trials: Traumatic Injuries
Concussion, Mild
Novel Protection Against Potential Brain, Hearing and Vision Injury During Blast Wave Exposure
The purpose of the study is to monitor changes in brain structure and function between the pre-training and post-training, in a population of tactical team members wearing the Device and compared to a similar population not…
- Trial name
- BLAST (NCT03017924)
- Testing
- Q collar
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Complex Regional Pain Syndrome (CRPS)
Relationship Between Complex Regional Pain Syndrome and Magnesium Depletion Score
Complex Regional Pain Syndrome (CRPS) is a condition triggered by trauma such as surgery or a fracture. It is characterised by pain and limited mobility that are disproportionate to the severity of the trauma and the clinical…
- Trial name
- NCT07093424
- Testing
- scoring
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Stress Disorders, Post-Traumatic
Mantram Repetition Meditation for Veterans With PTSD
The aim of this study was to determine the usefulness of a portable, meditation-based intervention called the Mantram Repetition Program (MRP) for Veterans with military-related posttraumatic stress disorder (PTSD).
- Trial name
- NCT01506323
- Testing
- Mantram Repetition Program (MRP), Present Centered Therapy (PCT)
- Where
- 2 sites in United States
- Volunteers
- 181 people
- Sponsor
- US Department of Veterans Affairs
Earthquake, Compassion Fatigue
Impact of Earthquake Trauma on Nurses' Compassion Fatigue: A Study From Kahramanmaraş, Turkey
This study investigates the impact of earthquake trauma on compassion fatigue among nurses working in emergency services following the devastating earthquakes on 6 February 2023, in Kahramanmaraş, Turkey.
- Trial name
- NCT06288880
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kilis 7 Aralik University
PTSD - Post Traumatic Stress Disorder, Trauma-related Nightmares
Validation of an Algorithm for Predicting Awakenings Associated With Trauma-related Nightmares, Based on the Analysis of Physiological Patterns in Military and Former Military Patients Suffering From Post-traumatic Stress Disorder
The goal of this clinical trial is to validate an artificial intelligence algorithm called CAUD-PIN (CAUchemar Detection on INdividualized Parameters) to predict nightmare-related awakenings in military personnel and veterans…
- Trial name
- CAUD-PIN (NCT07851480)
- Testing
- CAUD-PIN (CAUchemar Detection on INdividualized Parameters) - AI-based predictive algorithm forTrauma-related nightmare awakenings
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Traumatic Brain Injury | Patient
Impact of Inspired Oxygen Fraction on Outcome in Patients With Traumatic Brain Injury
Aim of the study is to investigate the impact of two different fractions of inspired oxygen (FiO2) on outcome in patients with severe traumatic brain injury (TBI).
- Trial name
- BRAINOXY (NCT01201291)
- Testing
- Normobaric oxygen
- Where
- 4 sites in Finland
- Volunteers
- 67 people
- Sponsor
- Kuopio University Hospital
Post-traumatic Stress Disorder
Using Reconsolidation Blockade to Treat Trauma Related Disorders After Paris Attacks: an Effectiveness Study
The purpose of this study is: (1) to examine the effectiveness of reconsolidation blockade as a treatment for trauma-related disorders, (2) to evaluate the feasibility of implementing this new treatment on a large scale in a…
- Trial name
- PARIS-MEM (NCT02789982)
- Testing
- β-adrenergic blocker propranolol, Treatment as usual
- Where
- 20 sites in France, Martinique
- Volunteers
- 364 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Borderline Personality Disorder, Stress Disorders, Post-Traumatic
Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder
Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity.
- Trial name
- NCT02517723
- Testing
- Narrative Exposure Therapy, Dialectical Behavior Therapy, Standard Inpatient Care
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH
Alcoholism, Post-Traumatic Stress Disorder
Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder
This study will investigate the use of sertraline (Zoloft) to decrease alcohol consumption and crime-related post-traumatic stress disorder in those individuals with both disorders.
- Trial name
- NCT00000446
- Testing
- sertraline (Zoloft)
- Where
- United States
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Traumatic Brain Injury
To Evaluate the Effect of Glibenclamide in Reducing Brain Edema of TBI
Brain edema is one of the main mechanisms of secondary brain injury and one factor in the prognosis of traumatic brain injury . The clinical study of glibenclamide in the treatment of brain edema after traumatic brain injury is…
- Trial name
- NCT05148403
- Testing
- glibenclamide
- Where
- 2 sites in China
- Volunteers
- 76 people
- Sponsor
- Beijing Tiantan Hospital
Pain
Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain
The purpose of the study is to evaluate the efficacy and safety of OraVescent fentanyl treatment compared to placebo treatment monthly over a 12-week treatment period in alleviating breakthrough pain (BTP) in opioid-tolerant…
- Trial name
- NCT00343733
- Testing
- OraVescent Fentanyl
- Where
- 21 sites in United States
- Volunteers
- 120 people
- Sponsor
- Cephalon
Post-traumatic Stress Disorder
Effectiveness of a Blended Care Parenting Intervention for Parents With PTSD (KopOpOuders-PTSD)
KopOpOuders-PTSD is a new preventive blended care intervention for parents with PTSD. The purpose of this study is to evaluate its effectiveness in improving parenting and preventing child mental health problems.
- Trial name
- NCT05237999
- Testing
- KopOpOuders-PTSD
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- Arkin
Post-traumatic Stress Disorder (PTSD), Trauma
Functional Brain Imaging in PTSD
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume.
- Trial name
- NCT02053532
- Testing
- Positron emission tomography/magnetic resonance imaging
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Nervous System Disorders
Dysport® Adult Upper Limb Spasticity
The purpose of this research study is to assess the efficacy of Dysport compared to placebo in improving muscle tone in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury.
- Trial name
- NCT01313299
- Testing
- Botulinum toxin type A
- Where
- 40 sites in United States, Belgium and 7 more
- Volunteers
- 243 people
- Sponsor
- Ipsen
Posttraumatic Stress Disorder
Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD)
The outcome of trauma treatment (Posttraumatic Stress Disorder - PTSD) may be influenced by which emotions that are predominant among current symptoms, e.g. fear, anger, guilt, shame.
- Trial name
- NCT00891098
- Testing
- Imaginal exposure, Imagery rescripting
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Modum Bad
Post Traumatic Stress Disorder PTSD
Inhaled Cannabis for Treatment of PTSD
The rationale for the use of inhalational cannabis to potentially treat PTSD symptoms is based on the many reports of cannabis attenuating PTSD symptom expression among individuals with PTSD, including veterans.
- Trial name
- NCT07224698
- Testing
- High THC Cannabis
- Volunteers
- 320 people
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
Traumatic Brain Injury
Magnetic Resonance Elastography in Patients With Acute Closed Traumatic Brain Injury
Traumatic brain injury (TBI) is a major public health issue, and intracranial hypertension in the acute phase remains a critical scientific issue.
- Trial name
- NCT04361578
- Testing
- Magnetic resonance elastography
- Volunteers
- 43 people
- Sponsor
- Xiangya Hospital of Central South University
PTSD - Post Traumatic Stress Disorder, Stress Disorder, Post Traumatic
Evaluation of the Effect of an Emergency Department Information Video on the Risk of Post-Traumatic Stress Disorder 30 Days After an Emergency Visit.
Post-traumatic stress disorder (PTSD) is a psychological disorder characterized by the re-experiencing of distressing symptoms, avoidance of traumatic memories and physiological hyperarousal in people who have been exposed to a…
- Trial name
- VISU (NCT06755606)
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Systemic Oxygenation vs ROS Formation in TBI Patients
ROS in TBI Patients in Relation to Level of Oxygenation.
This project an observational study performed on patients with severe Traumatic Brain Injury (TBI) treated at Neurosurgical ICU (NICU) at Karolinska University Hospital.
- Trial name
- ROS-TBI (NCT05101278)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Stockholm
Post Traumatic Stress Disorder
Written Exposure Therapy for Post-traumatic Stress Syndrome
To investigate if written exposure therapy is feasible for patients with post-traumatic stress disorder
- Trial name
- NCT04328935
- Testing
- WET
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
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