Clinical trials: Traumatic Injury
Sports Performance, Injury Prevention
Effect of Whole-body Photobiomodulation on Muscular Performance Enhancement.
Introduction: Photobiomodulation therapy (PBMT) is based on the emission of light ranging from red to near-infrared spectra by different devices based on diode lasers or light-emitting diodes.
- Conditions
- Sports Performance, Injury Prevention, Muscle Damage, Musculoskeletal Pain
- Trial name
- WBPME (NCT05989815)
- Testing
- Muscle damage protocol training, Photobiomodulation therapy (PBMT)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Major Depressive Disorder, Posttraumatic Stress Disorder
Comparing Group Therapies for Veterans With Depression and PTSD
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and PTSD. However, CBT is largely underutilized within Veteran Affairs Medical Centers (VAMCs) due to the cost…
- Trial name
- NCT03979040
- Testing
- Group Transdiagnostic Behavior Therapy, Group Disorder-Specific Therapy (G-DSTs)
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- VA Office of Research and Development
Patient Satisfaction, Sports Injury
Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic
This study will compare patient reported outcomes (PROs) of patients seen at virtual phone visits compared to in-person visits for 6 weeks, 12 weeks, and 6 months post-operative follow up at a sports medicine clinic.
- Conditions
- Patient Satisfaction, Sports Injury, Surgery, Orthopedic Disorder
- Trial name
- NCT05998148
- Testing
- virtual phone appointment visits
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jonathan Wu
Subarachnoid Hemorrhage, Intracranial Hemorrhage
Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study
Primary Objective: To determine the effects of a diabetes specific enteral formula compared to a standard formula supplemented with protein (isocaloric and isonitrogenous) on the mean blood glucose and glycemic variability in a…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Hemorrhage, Ischemic Strokes, Subdural Hematoma
- Trial name
- ANUS1014 (NCT01463878)
- Testing
- Glycerna, Jevity - Control Diet
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Eastern Virginia Medical School
Depression, Traumatic Brain Injury
Mindfulness-Based Cognitive Therapy Intervention to Treat Depression in Individuals With a Traumatic Brain Injury
The purpose of this study is to determine whether mindfulness-based cognitive therapy is effective in reducing depression symptoms in individuals who have experienced a traumatic brain injury.
- Trial name
- NCT00745940
- Testing
- MBCT for TBI
- Where
- 3 sites in Canada
- Volunteers
- 105 people
- Sponsor
- Lakehead University
Pressure Ulcer, Spinal Cord Injuries
Pressure Ulcer Healing With Microcyn
The purpose of this study is to test how well Microcyn™ works on Stage 3 and Stage 4 pressure ulcers compared to sterile saline among persons with spinal cord injury.
- Trial name
- NCT02001558
- Testing
- Microcyn, Sterile saline
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Alabama at Birmingham
Posttraumatic Stress Disorder, Moral Injury
Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury
Given the prevalence of posttraumatic stress disorder (PTSD) and moral injury in combat Veterans and the limitations to current treatments, novel approaches are needed to target both PTSD and moral injury and directly impact…
- Trial name
- NCT03906240
- Testing
- Moral Elevation intervention
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
PTSD
A Pilot Study Of Riluzole In Patients With Post Traumatic Stress Disorder (PTSD)
This open label study will evaluate the safety and efficacy of riluzole in patients with PTSD. Patients will receive riluzole 50mg twice per day orally for 12 weeks as outpatient, with a one month follow up at week 16.
- Trial name
- NCT02019940
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Upper Extremity Injury, Sport Injury
Throwers Ten Exercises On Upper Extremity Function and Explosive Power in Wheelchair Basketball and Basketball Players
Basketball is a challenging sport that requires participants to demonstrate physical fitness and special athletic skills at high levels.
- Conditions
- Upper Extremity Injury, Sport Injury, Shoulder Pain, Muscle Weakness
- Trial name
- NCT04019990
- Testing
- The effect of throwers ten exercise programme on wheelchair basketball and ambulant basketball players
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Respiratory Distress Syndrome, Adult, Sepsis
Early Insulin and Development of ARDS
Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) is a severe lung condition that causes respiratory failure. Symptoms usually develop within 24 to 48 hours of an original injury or illness, and people with…
- Conditions
- Respiratory Distress Syndrome, Adult, Sepsis, Hyperglycemia
- Trial name
- NCT00605696
- Testing
- Insulin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Stress Disorders, Post-Traumatic, Alcohol Abuse
Combined Treatment for Alcohol-Dependent Individuals With PTSD
This treatment intervention trial is designed for men and women with either alcohol misuse (e.g. hazardous or binge drinking) or alcohol use disorders (alcohol abuse or dependence) and comorbid PTSD.
- Conditions
- Stress Disorders, Post-Traumatic, Alcohol Abuse, Substance-Related Disorders
- Trial name
- NCT00262223
- Testing
- Seeking Safety, Sertraline
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- New York State Psychiatric Institute
Spinal Cord Injury, Sleep Disordered Breathing
Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI
The purpose of this study is to look at the effect of exciting using drugs to target a specific pathway in the body, that relies on a natural chemical the body produces called 'serotonin', in patients with spinal cord injury…
- Trial name
- REST-SCI (NCT02458469)
- Testing
- Buspirone, Trazodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Cognitive Training for PTSD
Posttraumatic stress disorder (PTSD) is a chronic, disabling condition that occurs in a subgroup of individuals after experiencing traumatic stress, and is common in Veterans seeking mental health treatment at the VA.
- Trial name
- NCT03316196
- Testing
- COGENT COGNITIVE TRAINING, Non training computer condition
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
TBI-Traumatic Brain Injury
Simvastatin for mTBI
Study of simvastatin in Iraq/Afghanistan Veterans with multiple blast exposure and mTBI. The study will measure substances in cerebrospinal fluid (CSF) that are related to dementing disorders.
- Trial name
- NCT01952288
- Testing
- simvastatin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Stomatitis
Evaluation of Efficacy and Mechanisms of an Antiinflammatory Intervention for Chemotherapy Related Mucosal Injury
This study consisted of two parts: the pilot study and the main study. The purpose of the pilot study is to demonstrate the effectiveness of planned laboratory techniques to assess for TNF-alpha gene expression from unstimulated…
- Trial name
- NCT00031551
- Testing
- Etanercept
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- National Institute of Nursing Research (NINR)
Posttraumatic Stress Disorder
Narrative Exposure Therapy (NET)
The purpose of this study is to learn more about Narrative Exposure Therapy for Justice Involved Veterans. This pilot study will examine the feasibility of this intervention in a justice-involved veteran population, and will see…
- Trial name
- NET (NCT03777553)
- Testing
- Narrative Exposure Therapy for Justice-Involved Veterans
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Musculoskeletal Injury
Fluoxetine Mitigation Mental Health Study for Patients With Musculoskeletal Trauma
Musculoskeletal trauma is one of the leading causes of disability in the United States and its negative quality of life impact extends beyond that of physical recovery.
- Trial name
- NCT04850222
- Testing
- Fluoxetine, Calcium
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Florida
Stress Disorders, Post-Traumatic
Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)
This study will explore the relationship between changes in plasma cortisol and symptom reduction resulting from individuals with posttraumatic stress disorder (PTSD) participating in an 8-week program of mindfulness-based…
- Trial name
- NCT01462045
- Testing
- Mindfulness-based exercise
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Alcoholism, Alcohol Dependence
Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone)
This study will evaluate naltrexone and cognitive-behavioral therapy treatments for alcohol dependence and post-traumatic stress disorder (PTSD).
- Conditions
- Alcoholism, Alcohol Dependence, Post-Traumatic Stress Disorder
- Trial name
- NCT00006489
- Testing
- Cognitive-Behavioral Therapy, Naltrexone
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- University of Pennsylvania
Post Traumatic Stress Disorder
Iloperidone for Symptoms of Arousal in Post Traumatic Stress Disorder (PTSD)
A Double-Blind Placebo-Controlled Random Order Crossover Pilot Study of Iloperidone for Symptoms of Arousal in PTSD.
- Trial name
- NCT01917318
- Testing
- Iloperidone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Colorado, Denver
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