Clinical trials: Traumatic Injury of Spine
Spinal Fractures
Effect and Essentiality of Vertebroplasty Surgery in Acute Vertebral Compression Fractures
Percutaneous vertebroplasty is now a common procedures of patients with acute osteoporotic vertebral compression fractures in medical units all over China, but the efficacy and essentiality of the surgery remain uncertain and is…
- Trial name
- NCT03360383
- Testing
- percutaneous vertebroplasty, conservative treatment
- Volunteers
- 400 people
- Sponsor
- Peking University People's Hospital
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Osteoporosis
Treatment of Childhood Osteoporosis With Alendronate (Fosamax)
Bones grow and stay strong through a continuous process of formation (building) and resorption (break down). When more bone is formed than resorbed, the density (level of calcium) in bone increases and the bones become stronger.
- Trial name
- NCT00001720
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Degenerative Disc Disease (DDD), Spinal Stenosis
PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials
This is a prospective, multi-center, observational Post-Market Clinical Follow-Up (PMCF) study designed to collect additional safety and clinical performance data on CE-marked Titania® spinal instrumentation and fusion systems…
- Conditions
- Degenerative Disc Disease (DDD), Spinal Stenosis, Spondylolisthesis, Spinal Deformities
- Trial name
- INFO SPINE (NCT07615491)
- Testing
- Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 561 people
- Sponsor
- Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co.
Spinal Fractures, Vertebral Compression Fractures
Prospective Comparative Study to Compare Safety and Effectiveness of Two Vertebral Compression Fracture Reduction Techniques
The purpose of this study is to compare the safety and effectiveness of the SpineJack® with the Kyphx Xpander® Inflatable Bone Tamp and support a non-inferiority finding for the use of SpineJack® VCF treatment system versus…
- Conditions
- Spinal Fractures, Vertebral Compression Fractures, Back Injuries, Osteoporosis
- Trial name
- SAKOS (NCT02461810)
- Testing
- Vertebral fracture surgery SpineJack®, Balloon Kyphoplasty
- Where
- 13 sites in France, Germany and 3 more
- Volunteers
- 152 people
- Sponsor
- Vexim SA
Traumatic Vertebral Fractures, Compression Fractures of the Spine
Comparison of Three Treatment Strategies for Traumatic AO Type A1 Vertebral Fractures
This retrospective study evaluates three different treatment approaches used for traumatic AO Spine Type A1 (A1) vertebral fractures: orthopedic bracing, percutaneous vertebroplasty, and spinal arthrodesis.
- Conditions
- Traumatic Vertebral Fractures, Compression Fractures of the Spine, AO Type A1 Vertebral Fracture, Spinal Trauma
- Trial name
- TRAUMA-A1 (NCT07471568)
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- University of Valencia
Whiplash Injuries, Whiplash Injury of Cervical Spine
Clinical Efficacy of Diazepam After Whiplash
Whiplash injury is very common and lot of patients which suffered the injury have chronic symptoms despite different treatment options. One of main symptoms include muscle spasm and pain caused by neck movement.
- Trial name
- NCT05041985
- Testing
- Diazepam Tablets
- Where
- Bosnia and Herzegovina
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Edin Mešanović
Whiplash Injury of Cervical Spine
Effects of a Mobile App on Adherence to Daily Exercise and Recovery After Whiplash Injury
This study investigates the effect of daily mobile app reminders to exercise in conjunction with standard physical therapy on adherence to exercise and recovery after whiplash injury of the neck.
- Trial name
- NCT05704023
- Testing
- Reminder to exercise
- Where
- Croatia
- Volunteers
- 68 people
- Sponsor
- Blaz Barun
Cervical Spine Surgery
Laryngoscope Asssited Lightwand Intubation
To evaluate the success rate for intubation of laryngocope assisted lightwand intubation.
- Trial name
- NCT01950702
- Testing
- Laryngoscope assisted lightwand intubation, Lightwand intubation
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Erectile Dysfunction, Sexual Dysfunction
BAY38-9456 - Supportive Trial for Spinal Injury
BAY 38-9456 10 mg and 20 mg can be given as safe and efficacious medications to patients with spinal cord injury suffering from erectile dysfunction, and that erectile dysfunction can be improved by uptitration to BAY 38-9456 20…
- Conditions
- Erectile Dysfunction, Sexual Dysfunction, Spinal Cord Injury
- Trial name
- NCT00652262
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 3 sites in Japan
- Volunteers
- 32 people
- Sponsor
- Bayer
Spine Disease, Spinal Stenosis
CEUS For Intraoperative Spinal Cord Injury
Spinal cord injury following posterior decompression in patients suffering from chronic, cervicothoracic spinal cord compression is a known complication with multiple etiologies.
- Conditions
- Spine Disease, Spinal Stenosis, Spinal Injury, Spinal Cord Diseases
- Trial name
- NCT05530798
- Testing
- Definity Perflutren Lipid Microsphere Ultrasound Contrast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Osteoporosis, Vitamin C Deficiency
Link Between ASCorbemia Level and Osteoporosis
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis.
- Conditions
- Osteoporosis, Vitamin C Deficiency, Vertebral Fractures
- Trial name
- ASCO (NCT07660484)
- Testing
- Plasma vitamin C assessment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Postmenopausal Osteoporosis, Spinal Fractures
Epidemiology, Identification Rate and Treatment Penetration of Osteoporotic Vertebral Fractures in Switzerland
In Switzerland, the prevalence of vertebral fractures in community- dwelling women is unknown and the published data from the Swiss hospitals statistics represent only the tip of the iceberg.
- Trial name
- SwOF (NCT02234414)
- Where
- 3 sites in Switzerland
- Volunteers
- 303 people
- Sponsor
- Prof. Dr. med. Kurt Lippuner
Type 2 Diabetes
Comparison of Bone Quality in Type 2 Diabetic Patients With a Non-diabetic Control Population
Patients with type 2 diabetes have many complications in different organs. These complications are extremely frequent and severe: cardiovascular and renal disease, visual impairment, and, more recently, complications affecting…
- Trial name
- DIABONE (NCT02797314)
- Testing
- Bone biopsies
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical…
- Conditions
- Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Scoliosis or Tumors
- Trial name
- NCT02826889
- Testing
- Philips Intelivue MP70 monitor, Pleth Variability Index (PVI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Spinal Fractures, Anesthesia, Regional
Effectiveness of Erector Spinae Block in Kyphoplasty
As of October 2019, when the investigators received the approval of the ethics committee, patients who were decided to undergo kyphoplasty with vertebral compression fracture will be included in the study.
- Conditions
- Spinal Fractures, Anesthesia, Regional, Anesthetics, Local, Analgesia
- Trial name
- NCT04201678
- Testing
- CLIA Group (conventional local anesthesia infiltration), EPIAA Group (Extrapedicular infiltration anesthesia), ESP Group (Erector Spina Block)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gulhane School of Medicine
Cervical Spine Injury, Emergencies
CT C-spine Audit and Feedback
This is a prospective quality improvement study to assess the effect of using an audit-and-feedback process for emergency providers on utilization of computed tomography of the cervical spine.
- Conditions
- Cervical Spine Injury, Emergencies, Trauma
- Trial name
- NCT05711134
- Testing
- Audit and Feedback on Individual Practice Patterns
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Massachusetts, Worcester
Hip Fracture, Vertebral Fracture
Norwegian Capture the Fracture Initiative
The main aim is to assess the effectiveness of introducing a standardized intervention program for treatment of patients with a fragility fracture as measured by changes in the fracture rates and the mortality.
- Conditions
- Hip Fracture, Vertebral Fracture, Other Low-trauma Fracture
- Trial name
- NoFRACT (NCT02536898)
- Testing
- Fracture Liaison Service, Current treatment
- Where
- 7 sites in Norway
- Volunteers
- 94,260 people
- Sponsor
- Oslo University Hospital
Orthostatic Hypotension, Spinal Cord Injuries
A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
The purpose of this study is to determine how blood pressure and blood flow are controlled during head-up tilt in a semi-upright position.
- Trial name
- NCT00248807
- Testing
- 1.25 mg enalaprilat IV, Head up tilt (HUT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Injuries, Spinal Cord
Clinical Trial to Evaluate One-to-one Peer Mentoring
The research will examine the effects of enhanced peer mentor interactions on facilitating a successful transition to community living following traumatic spinal cord injury (SCI).
- Trial name
- NCT02274649
- Testing
- one-to-one peer mentoring, general peer support
- Volunteers
- 194 people
- Sponsor
- Shepherd Center, Atlanta GA