Clinical trials: Traumatic Lower Extremity Amputation
Amputation of Lower Limb Below Knee, Amputation, Traumatic
REsistance and LOADing Exercise for Bone Health
Lower limb amputation, often resulting from military conflict and road traffic accidents, is associated with reduced hip bone mineral density (BMD) and increased risk of hip fractures.
- Conditions
- Amputation of Lower Limb Below Knee, Amputation, Traumatic, Amputation, Limb Loss
- Trial name
- RELOAD (NCT07817381)
- Testing
- Resistance and high-impact exercise training
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Traumatic Amputation of Lower Extremity
Treadmill Training With Lower Extremity Amputees
Many people with a leg amputation have difficulty walking even after they have finished their rehabilitation. The purpose of this study is to see if a large amount of walking practice on a treadmill can improve functional…
- Trial name
- NCT01419288
- Testing
- Treadmill Training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stony Brook University
Amputation; Traumatic, Leg, Lower
Whole-body Vibration Without Visual Feedback on Postural Steadiness in Unilateral Trans-femoral Traumatic Amputees
This study will investigate the effects of Whole-body vibration without visual feedback on postural steadiness in unilateral trans-femoral traumatic amputees.
- Trial name
- NCT06284733
- Testing
- Whole-body vibration plus conservative care, conservative care
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- MTI University
Traumatic Amputation of Lower Extremity
Functional Electrical Stimulation Use in Trans-tibial Amputations
The purpose of this study is to demonstrate the efficacy of functional electrical stimulation (FES) for trans-tibial amputees. The investigators aim to demonstrate that providing three months of FES intervention will increase…
- Trial name
- NCT02931396
- Testing
- FES
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alicia Koontz
Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
Functional Outcomes in Dysvascular Transfemoral Amputees
In older adults, poor circulation in the lower extremities leads to serious health complications including limb loss. In addition, individuals with dysvascular disease also suffer from other co-morbidities like diabetes, coronary…
- Trial name
- CLEG (NCT01537211)
- Testing
- C leg compared to subject's mechanical leg (Otto Bock)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Traumatic Amputation of Lower Extremity
Intraosseous Transcutaneous Amputation Prosthesis
Direct Skeletal Fixation of Prosthetic Limbs Following Trans-Femoral Amputation - Study of an Intraosseous Transcutaneous Amputation Prosthesis (ITAPTM).
- Trial name
- (ITAP) (NCT02491424)
- Testing
- Direct skeletal fixation of ITAP to lower limb amputees.
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Stryker Orthopaedics
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees
The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT06194838
- Testing
- Ossur Power Knee, Reboocon Intuy Knee
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Liberating Technologies, Inc.
Phantom Limb, Residual Limb Pain
Acupuncture for the Treatment of Phantom Limb and Residual Limb Pain After Amputation
The purpose of this study is to identify the best treatment sequence and combination of acupuncture points for the treatment of phantom limb or residual limb pain in the traumatic/surgical amputee.
- Conditions
- Phantom Limb, Residual Limb Pain, Traumatic Amputation, Amputation
- Trial name
- NCT00388752
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Walter Reed Army Medical Center
Amputation, Traumatic
Relationship Between Gait Variability and Sensation
Twenty individuals who were referred to receive physiotherapy will be participants of the study. Participants with lower limb loss will evaluate with the following assessment tools: Demographic datas; age, gender, height, body…
- Trial name
- NCT02934074
- Testing
- No intervention
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Amputation, Diabetes Complications
Study to Determine if Different Prosthetic Sockets Effect How Much Oxygen is in the Tissue of Lower Limb Amputees While They Are Walking
Amputee gait produces periodic occlusion of residual limb blood vessels. During the stance phase of gait, body weight cause the prosthesis to compresses the soft tissue of the residual limb and occlude blood flow.
- Conditions
- Amputation, Diabetes Complications, Leg Injuries, Traumatic Amputation
- Trial name
- NCT00985842
- Testing
- Pe-Lite and sleeve suspension socket, Total Surface bearing a socket with a sleeve suspension but without suction, Total surface bearing suction socket with a pin lock suspension
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Spinal Root and Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees
The goals of this study are to provide sensory information to amputees and reduce phantom limb pain via electrical stimulation of the lumbar spinal cord and spinal nerves.
- Trial name
- SCS-LL (NCT03027947)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
Amputation
Kinesiophobia and Associated Factors in Patients With Traumatic Lower Extremity Amputation
There are limited studies examining kinesiophobia and factors associated with kinesophobia in patients with lower limb amputation.
- Trial name
- NCT04775667
- Testing
- questionnaires for clinical assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Lower Extremity Amputation, Trans-Tibial Amputation
Kinematics of Ewing Amputees
The agonist-antagonist myoneural interface (AMI) construct, known as the Ewing amputation at the trans-tibial level, has been shown to create a bi-directional neural communication platform as a means of controlling and…
- Conditions
- Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation, Agonist-Antagonist Myoneural Interface
- Trial name
- NCT06371209
- Testing
- Modified Amputation, Standard Amputation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Brigham and Women's Hospital
Amputation, Amputation; Traumatic, Limb
Low Cost Socket for Lower Limb Amputees
The purpose of this research is to test an investigational fabrication system for transtibial prostheses. This fabrication method will be tested for comfort and function to determine feasibility of use for amputees in developing…
- Conditions
- Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic
- Trial name
- NCT04725461
- Testing
- Low cost lower limb prosthetic socket
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Transtibial Amputation, Peripheral Artery Disease
Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation
The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely contribute to disabling sequelae including secondary…
- Conditions
- Transtibial Amputation, Peripheral Artery Disease, Diabetes Mellitus
- Trial name
- GEM (NCT03995238)
- Testing
- Error-augmentation gait training, Error-correction gait training, Supervised walking
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Amputation; Traumatic, Limb, Lower
Validity and Reliability Study of Glittre Activities Of Daily Living Test in Amputees
Glittre activities of daily living test is used in different populations. The test, which is valid and reliable in different populations, has not been validated in amputees.
- Trial name
- NCT05444868
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Eastern Mediterranean University
Amputation, Amputation, Traumatic
No Power Bionic Lower Extremity Prosthesis
Typically people need separate prosthetic feet for running and walking. To bridge the gap, this study will test the Compliant Adaptive Energy Storage and Return (CAESAR) foot.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Leg, Lower
- Trial name
- NCT04070105
- Testing
- Compliant Adaptive Energy Storage and Return Foot, AllPro
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Michigan
Amputation; Traumatic, Leg, Lower, Between Knee and Ankle
Comparison Between Three Types of Prosthetic Feet
One Solid Ankle Cushion Heel (SACH) and two Dynamic Elastic Response (DER) prosthetic feet will be tried six times in random order by the patient.
- Trial name
- ProSto (NCT03046394)
- Testing
- C-SACH, B-DER, A-DER
- Where
- Slovenia
- Volunteers
- 1 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Amputation, Amputation of Lower Limb
Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain
The goal of this Registry is to see how the device is used when freezing nerves during an amputation procedure.
- Conditions
- Amputation, Amputation of Lower Limb, Amputation of Upper Limb, Amputation, Limb Loss
- Trial name
- VANISH (NCT06908538)
- Testing
- cryoablation
- Where
- 6 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- AtriCure, Inc.
Amputation Wound, Traumatic Amputation of Toe
Longitudinal Study of Weight Change Following Lower Limb Amputation
The purpose of this study is to assess weight change in a population of Veterans with amputations. Little is known about the how weight changes following an amputation.
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Trial name
- NCT00932399
- Where
- United States
- Volunteers
- 4,549 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development