Clinical trials: Traumatic Optic Neuropathy
Eye Diseases, Optic Nerve Damage
Comparison of Efficacy and Safety of Mitomycin and Aflibercept Used to Support Primary Trabeculectomy.
Comparison of efficacy and safety of Mitomycin and Aflibercept used to support primary trabeculectomy - a prospective, randomized trial in patients with open-angle glaucoma undergoing surgery.
- Conditions
- Eye Diseases, Optic Nerve Damage, Glaucoma Surgery
- Trial name
- NCT03766425
- Testing
- Aflibercept, Mitomycin
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- Medical University of Lublin
Optic Nerve Injuries, Sellar Tumor
Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches
Assessing the function of the optic nerve is paramount during various neurosurgical procedures. Effective optic nerve monitoring has remained elusive as Visual Evoked Potentials (the current existing tool) provides only diffuse…
- Conditions
- Optic Nerve Injuries, Sellar Tumor, Skull Base Neoplasms
- Trial name
- NCT06495580
- Testing
- Optic Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Traumatic Optic Neuropathy
Surgery for Traumatic Optic Neuropathy
The pathophysiology of Traumatic Optic Neuropathy (TON) include a primary and secondary mechanism of injury. At present, no studies validate a particular approach to the management of TON.
- Trial name
- NCT02711982
- Testing
- Optic canal and optic nerve sheath decompression, methylprednisolone
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Shanghai Changzheng Hospital
Ischemic Optic Neuropathy, Optic Neuritis
Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.
The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging
- Conditions
- Ischemic Optic Neuropathy, Optic Neuritis, Compressive Optic Neuropathy, Traumatic Optic Neuropathy
- Trial name
- NCT05353413
- Testing
- Neuroimaging, VEP - visual evoked potential, Ophthalmology examination.
- Where
- Poland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Normal Tension Glaucoma, High Tension Glaucoma
Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma
The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.
- Trial name
- NCT01488032
- Volunteers
- 44 people
- Sponsor
- Technische Universität Dresden
Neurologic Disorders, Nervous System Diseases
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will…
- Conditions
- Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders
- Trial name
- NEST (NCT02795052)
- Testing
- Intravenous and Intranasal BMSC
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Non-arteritic Ischemic Optic Neuropathy, Optic Nerve Injuries
Safety and Efficacy Study of RPh201 Treatment of Ischemic Optic Neuropathy (ION).
The study objectives are to assess any changes in visual acuity and visual field observed following the administration of RPh201 during an overall treatment period of at least 13 consecutive weeks with an option to extended the…
- Trial name
- NCT02045212
- Testing
- RPh201
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Regenera Pharma Ltd
Benign Intracranial Hypertension
Axial Length and Central Corneal Thickness in Benign Intracranial Hypertension
Patients in for treatment of benign intracranial hypertension will undergo two tests that are not routinely performed for these patients: central corneal thickness and axial length of the eye.
- Trial name
- NCT02541994
- Testing
- Pachette3, Lenstar-Think
- Volunteers
- 5 people
- Sponsor
- Ochsner Health System