Clinical trials: Traumatic Wound Infection
Sepsis, ARDS
The Effect of Positive End Expiratory Pressure on Central Venous Pressure Among Patients With Different Lung Compliance
To observe the effect of PEEP on CVP among patients with different respiratory compliance
- Conditions
- Sepsis, ARDS, Traumatic Brain Injury
- Trial name
- NCT03341572
- Testing
- 5,10 and 15cmH2O positive end expiratory pressure
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jingyuan,Xu
PTSD, Depression
Writing to Alleviate Violence Exposure for Transgender Women (WAVE-TW)
WAVE - TW (Writing to Alleviate Violence Exposure for Transgender women living with HIV) is an intervention development study which aims to assess the feasibility and acceptability of a proposed trauma writing and adherence…
- Conditions
- PTSD, Depression, Virus, Human Immunodeficiency
- Trial name
- WAVE-TW (NCT04305977)
- Testing
- WAVE-TW
- Where
- United States
- Sponsor
- University of Miami
Respiratory Failure, Respiratory Arrest
Postoperative Respiratory Abnormalities
The study aims to determine how historical cases of respiratory abnormalities are documented by clinicians in the electronic health records (EHR) of Memorial Hermann Healthcare System (MHHS) inpatient facilities.
- Conditions
- Respiratory Failure, Respiratory Arrest, Respiratory Distress Syndrome, Acute Respiratory Failure
- Trial name
- AI-ARF (NCT04079829)
- Testing
- Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Efficacy Care R&D Ltd
Stress Disorders, Post-Traumatic, HIV Infections
Stress-Reducing Interventions in HIV+ Patients: Pilot
The primary aim of this project is to examine the efficacy of prolonged exposure (PE) therapy at reducing HIV-related PTSD symptoms, increasing adherence to antiretroviral medication regimens, and increasing health-related…
- Trial name
- PEACH (NCT00599599)
- Testing
- Prolonged Exposure Therapy
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Kent State University
Traumatic Brain Injury, Trauma
Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury
Traumatic brained injured (TBI) patients frequently suffered from glucocorticoid insufficiency that is associated with a raise in the rate of pneumonia.
- Conditions
- Traumatic Brain Injury, Trauma, Adrenal Insufficiency, Pneumonia
- Trial name
- Corti-TC (NCT01093261)
- Testing
- Hydrocortisone Fludrocortisone
- Where
- 18 sites in France
- Volunteers
- 336 people
- Sponsor
- Nantes University Hospital
Stress Disorders, Post-Traumatic, Sexually Transmitted Infection (STI) Prevention
Cognitive Processing Therapy to Treat PTSD and Sexually Transmitted Infections Among Men Who Have Sex With Men
Gay, bisexual, queer, and other men who have sex with men (GBM) continue to bear a disproportionate burden of the sexually transmitted and blood-borne infections (STBBI), largely attributable to efficient transmission during…
- Trial name
- CPT-T (NCT06463431)
- Testing
- Cognitive Processing Therapy
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- Toronto Metropolitan University
Traumatic Brain Injury, Decompressive Craniectomy
Study on the Efficacy of Long-term Drainage of Subdural Effusion After Decompressive Craniectomy
Drilling or puncture drainage is commonly used in TBI patients with subdural effusion following decompressive craniectomy who fail to respond to conservative treatment, but there is no exact regulation or guideline recommendation…
- Conditions
- Traumatic Brain Injury, Decompressive Craniectomy, Subdural Effusion
- Trial name
- NCT06391203
- Testing
- Long-term Drainage, Short-term Drainage
- Where
- China
- Volunteers
- 160 people
- Sponsor
- RenJi Hospital
Ventilator-associated Pneumonia, Traumatic Brain Injury
Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury
This randomized controlled trial will compare closed versus open endotracheal suctioning techniques for preventing ventilator-associated pneumonia (VAP) in adults with severe traumatic brain injury (TBI) who need mechanical…
- Trial name
- NCT07883083
- Testing
- Closed endotracheal suction system, Open endotracheal suction
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Minia University
Finger Injuries
Silicone Finger Cap ("Silikonfingerling")
Amputation injuries of the fingertip are common in all ages. For decades it is known that conservatively treated fingertips can regenerate skin and soft tissues to form a functionally and cosmetically excellent new fingertip.
- Trial name
- NCT03089060
- Testing
- Silicone Finger cap, Film Dressing
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Orthopädie- und Rehatechnik Dresden GmbH
HIV/AIDS, Depression
Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States
This pilot randomized clinical trial will randomize 60 participants 1:1 to either enhanced usual care or to adapted Common Elements Treatment Approach (CETA), a counseling intervention for HIV care engagement plus depression…
- Conditions
- HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- TRACE (NCT04163341)
- Testing
- Adapted Common Elements Treatment Approach
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Michael J Mugavero, MD
Depression, Burnout, Professional
Health cAre woRkers exposeD to COVID-19
Health care workers working in hospital or nursing home for elderly people involved in the coronavirus epidemic are facing several challenges such as direct exposure and involvement in the resolution of major public health…
- Conditions
- Depression, Burnout, Professional, Post Traumatic Stress Disorder
- Trial name
- HARD-COVID19 (NCT04570202)
- Testing
- EMDR
- Where
- 2 sites in France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Tours
Neurogenic Dysphagia, Traumatic Brain Injury
Register Study: Implementation of Pharyngeal Electrostimulation Therapy for the Treatment of Acute Neurogenic Dysphagia
Neurogenic dysphagia occurs with disruption of neurological systems or processes involved in the execution of coordinated and safe swallowing.
- Conditions
- Neurogenic Dysphagia, Traumatic Brain Injury, Stroke, Dysphagia
- Trial name
- R:IphEst (NCT05190718)
- Testing
- Pharyngeal electrostimulation
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Karl Landsteiner University of Health Sciences
COVID-19, Coronavirus Infections
Functional Outcomes in COVID-19 Survivors and Use of a Digital Platform for Rehabilitation
COVID-19, an acute respiratory disease caused by coronavirus-2 (SARS-CoV-2), and in most cases, causes mild to moderate symptoms of fever, cough and dyspnea.
- Conditions
- COVID-19, Coronavirus Infections, Exercise Therapy
- Trial name
- NCT04695301
- Testing
- Rehabilitation protocol through a digital platform
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Hospital Israelita Albert Einstein
HIV, AIDS
Intervention Program to Address PTSD in People Living With HIV
The goal of this randomised controlled trial is to evaluate the efficacy of an integrated intervention program on post-traumatic stress disorder (PTSD) symptoms and related physiological and psychological indicators of people…
- Conditions
- HIV, AIDS, Mindfulness-based Stress Reduction, China
- Trial name
- NCT05588596
- Testing
- Trauma Resiliency Mindfulness-Informed Intervention
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Central South University
TBI (Traumatic Brain Injury), Status Epilepticus
Augmented Renal Clearance in Neurocritical Care
Stroke, severe brain injury, uncontrolled seizures and brain infections are the most common life-threatening neurological illnesses in the world with an estimated combined annual hospital management cost of up to 44 billion…
- Conditions
- TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC)
- Trial name
- Neuro-ARC (NCT07410624)
- Where
- 3 sites in United States, Canada
- Volunteers
- 512 people
- Sponsor
- University of Alberta
Phantom Limb Pain After Amputation, Chronic Pain Due to Injury
Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma
War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT).
- Conditions
- Phantom Limb Pain After Amputation, Chronic Pain Due to Injury, Postoperative Pain, Trauma (Including Fractures)
- Trial name
- NPWT-Pain Stud (NCT07475897)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Posttraumatic Stress Disorder
Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers
Healthcare workers and COVID-19 patients may experience psychological distress consequent to the pandemic, and are at particularly elevated risk for experiencing posttraumatic stress disorder (PTSD), based on evidence from…
- Trial name
- NCT04887116
- Testing
- Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Sexually Transmitted Diseases
Evaluation of the Care Path of Patients Who Have Been Sexually Assaulted
The main objective of this study is to describe the care pathway of patients presenting in the medico-judicial unit of the Raymond Poincaré Hospital in Garches, France, following a complaint for sexual assault and suggest ways to…
- Trial name
- AS UMJ/SMI RPC (NCT04078789)
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism With High Cognitive Abilities, COVID-19 Pandemic
The Impact of Covid-19 Pandemic On The Children With Autism Spectrum Disorder
The Covid-19 outbreak has caused families and individuals to change their life routines and eating habits, and has affected their psychology, especially for children with autism, due to the change in their routines.
- Trial name
- NCT05197634
- Testing
- Not Applicable (observation)
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Istanbul University
PTSD - Post Traumatic Stress Disorder, Sepsis
The Effect of Early Intervention on the Incidence of Posttraumatic Stress Disorder After Intensive Care Hospitalization Due to Sepsis
In recent years, the survival rate among intensive care patients has improved due to advancements in diagnosing severe infections and the use of broad-spectrum antibiotics.
- Conditions
- PTSD - Post Traumatic Stress Disorder, Sepsis, ICU
- Trial name
- NCT07707765
- Testing
- Psychiatric interview
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Barzilai Medical Center