Clinical trials: Treated Hypertension
Insomnia, Hypertension
Impact of Eszopiclone on Blood Pressure in Patients With Insomnia and Hypertension (PRYSMA-HTN)
Insomnia is a common sleep disorder characterized by difficulty falling asleep, staying asleep, or both, despite appropriate opportunities for getting sleep.
- Trial name
- PRYSMA-HTN (NCT07018557)
- Testing
- Eszopiclone 3 mg
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Hypertension, Portal
A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)
This study is open to adults with liver cirrhosis and high blood pressure in the portal vein (main vessel going to the liver). The purpose of this study is to find out whether a medicine called Avenciguat helps people with this…
- Trial name
- NCT05161481
- Testing
- Avenciguat (BI 685509)
- Where
- 45 sites in United States, Argentina and 20 more
- Volunteers
- 80 people
- Sponsor
- Boehringer Ingelheim
Chronic Thromboembolic Pulmonary Hypertension
A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment
Selexipag is available in many countries for the treatment of pulmonary arterial hypertension (PAH). Due to the similarities between PAH and chronic thromboembolic pulmonary hypertension (CTEPH) and the observed efficacy of other…
- Trial name
- SELECT (NCT03689244)
- Testing
- Selexipag
- Where
- 162 sites in United States, Argentina and 29 more
- Volunteers
- 128 people
- Sponsor
- Actelion
Hypertension
The Sympara VIBE Study for Hypertension
The purpose of the VIBE study is to evaluate the efficacy and safety of the Sympara Therapeutic System in the treatment of hypertension
- Trial name
- VIBE (NCT02250495)
- Testing
- Sympara Therapeutic System
- Where
- 3 sites in Australia
- Volunteers
- 8 people
- Sponsor
- Sympara Medical, Inc.
Hypertension
Cornell Translational Behavioral Science Research Consortium: Hypertension Qualitative Study
To explore the meaning, causes and treatment of hypertension in eligible patients. In addition the cultural, social, and psychological factors that either facilitate or serve, as barriers to behavioral change will be illuminated…
- Trial name
- NCT00227175
- Testing
- Semi-structured, open ended interview
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Pulmonary Arterial Hypertension
A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension
The goal of this clinical trial is to learn if empagliflozin works to treat patients with pulmonary arterial hypertension. It will also learn about the safety of empagliflozin.
- Trial name
- NCT06554301
- Testing
- empagliflozin in treatment pulmonary aerterial hypertension
- Where
- China
- Volunteers
- 72 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertension
Corever in the Treatment of Hypertension
The study primarily aims to compare the effects of two doses of Corever with placebo in patients with hypertension.
- Trial name
- NCT02432937
- Testing
- Corever
- Where
- 8 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- TSH Biopharm Corporation Limited
Hypertension
An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Patients With Type II Diabetes
This study will examine the ability of olmesartan medoxomil to lower the blood pressure of patients with Type II diabetes and high blood pressure.
- Trial name
- NCT00403481
- Testing
- olmesartan medoxomil, Olmesartan medoxomil plus Hydrochlorothiazide
- Where
- 27 sites in United States
- Volunteers
- 192 people
- Sponsor
- Daiichi Sankyo
Glaucoma, Acupuncture
Clinical Evaluation of Acupuncture in Treating Glaucoma
The present study predicts that acupuncture or electroacupuncture can reduce intraocular pressure and also can improve quality of life in patients with glaucoma.
- Trial name
- NCT04157530
- Testing
- wang-bu-liu-xing, acupuncture, Electroacupuncture
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- China Medical University Hospital
Pulmonary Hypertension
Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device
This study will assess the impact of sacubitril/valsartan on elevated pulmonary artery (PA) pressures in patients with heart failure (HF) with preserved ejection fraction (HFpEF), measured using a previously implanted hemodynamic…
- Trial name
- ARNIMEMS-HFpEF (NCT04753112)
- Testing
- Sacubitril / Valsartan Oral Tablet [Entresto]
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Germans Trias i Pujol Hospital
Hypertension, Medicine, Chinese Traditional
The Efficacy of Qianglidingxuan Tablets in the Treatment of Hypertension
Research purpose: This study was a multicenter, randomized, double-blind, placebo-controlled, post-marketing clinical study in Chinese patients with essential hypertension to evaluate the efficacy and safety of Qianglidingxuan…
- Trial name
- NCT05521282
- Testing
- Treatment group
- Where
- China
- Volunteers
- 269 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Hypertension
Blood Pressure Control of Nifedipine GITS 60mg Treatment in Chinese Hypertensive Subjects Uncontrolled on Starting-dose Mono-therapyo-therapy.
To evaluate antihypertensive efficacy and tolerability of Nifedipine GITS 60mg treated for 8 weeks in Chinese hypertensive subjects who failed to achieve BP control with the starting-dose antihypertensive monotherapy.
- Trial name
- ADEPT (NCT02413515)
- Testing
- Nifedipine (Adalat GITS, BAY1040)
- Where
- 14 sites in China
- Volunteers
- 278 people
- Sponsor
- Bayer
Pulmonary Arterial Hypertension
Epoprostenol for Injection in Pulmonary Arterial Hypertension
This is a prospective, multi-center, open-label, randomized, Phase IV exploratory study comparing safety, tolerability, pharmacokinetics, and effectiveness of ACT-385781A and Flolan (epoprostenol sodium) in patients with…
- Trial name
- EPITOME-1 (NCT01105091)
- Testing
- ACT-385781A (Actelion Epoprostenol), Flolan®
- Volunteers
- 30 people
- Sponsor
- Actelion
Pulmonary Arterial Hypertension (PAH)
Ambrisentan for Early Low-Risk Pulmonary Arterial Hypertension
This is an investigator-initiated, multicenter, randomized, double-blind, placebo-controlled clinical trial.
- Trial name
- ALEPH (NCT06987097)
- Testing
- Ambrisentan
- Volunteers
- 410 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypertension
Effects of Laser Acupuncture Treatment in Hypertension Haemodialysis Patients
The purpose of this study is to find the effect of acupuncture laser therapy on Blood Pressure in Hypertension Haemodialysis Patients
- Trial name
- NCT07170397
- Testing
- Acupuncture Laser Therapy
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Sinai University
Ocular Hypertension, Primary Open Angle Glaucoma of Both Eyes
Is the Reduction in IOP After Treatment of 180 Degrees Equivalent to Treatment of 360 Degrees With SLT?
The study is a prospective randomised controlled intervention comparing the intraocular pressure outcomes following Selective Laser Trabeculoplasty (SLT) treatment of 180 degrees SLT compared to 360 degrees in treatment naive…
- Conditions
- Ocular Hypertension, Primary Open Angle Glaucoma of Both Eyes, Intraocular Pressure
- Trial name
- SLT (NCT03529591)
- Testing
- Selective laser trabeculoplasty (SLT), Selective laser trabeculoplasty
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Western University, Canada
Medication Non-adherence
Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages
Uncontrolled hypertension is a major cause of morbidity and mortality and many patients fail to take their antihypertensive medication as prescribed.
- Trial name
- AIM@BP (NCT02454660)
- Testing
- SMS (Text messages)
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Glaucoma
VW-50 Feasibility Study
An investigator-initiated 10-participant Feasibility Study to assess a novel glaucoma drainage implant, VW-50.
- Trial name
- NCT07730424
- Testing
- Surgical implantation of VW-50
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Melbourne Eye Specialists
Intracranial Hypertension
Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure
The purpose of this study is to determine whether mannitol is as effective as hypertonic saline solution in the treatment of elevated intracranial pressure in patients with brain injury.
- Trial name
- NCT00447018
- Testing
- 20% mannitol, 7.45% hypertonic saline solution
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
Hypertension
Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension
The purpose of this study is to investigate the efficacy and safety of a fixed-dose combination of perindopril 5 mg /indapamide 1.25 mg / amlodipine 5 mg compared to the free combination of the same components (perindopril 4 mg /…
- Trial name
- NCT05820880
- Testing
- Fixed [Per/Ind/Aml], Free [Per/Ind + Aml]
- Where
- 42 sites in China
- Volunteers
- 532 people
- Sponsor
- Institut de Recherches Internationales Servier