Clinical trials: Treated Retina Detachment
Retina Detachment
Pneumatic Retinopexy for Severe Bullous Retinal Detachment
To compare the efficacy and safety outcomes of scleral buckling (SB) and drainage-injection-pneumoretinopexy (DIP), a modified pneumatic retinopexy technique, in which, before injecting the gas, the drainage of the subretinal…
- Trial name
- NCT04139746
- Testing
- Scleral Buckling, Drainage-Injection-Pneumoretinopexy
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Università degli Studi di Brescia
Pigment Epithelial Detachment
iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV)
LT1009-Oph-002 is a Phase 1b study designed to evaluate the safety and potential efficacy of iSONEP following one, two or three injections of iSONEP, as needed, for the treatment of Pigment Epithelial Detachment (PED) secondary…
- Trial name
- PED (NCT01334255)
- Testing
- iSONEP (sonepcizumab/LT1009)
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Lpath, Inc.
Retinal Detachment
Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery
This study is indicated for patients with extended rhegmatogenous retinal detachment (RRD) (≥ 2 quadrants) with macula OFF lasting 7 days or less, pseudophakic or aphakic, and scheduled to undergo surgical intervention with…
- Trial name
- UDCA (NCT06294847)
- Testing
- Ursolvan
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Hopital Foch
Macular Holes, Retinal Detachment
A Study of a New Surgical Treatment of Macular Hole Retinal Detachment in High Myopia
This study evaluates the surgical outcomes of inverted internal limiting membrane insertion combined with air tamponade in the treatment of macular hole retinal detachment (MHRD) in high myopia, and also to compare the treatment…
- Conditions
- Macular Holes, Retinal Detachment, High Myopia
- Trial name
- NCT03383731
- Testing
- Group 1, Group 2
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy
Intravitreal Infliximab for Proliferative Vitreoretinopathy
Proliferative vitreoretinopathy (PVR) is the most common cause for failure of rhegmatogenous retinal detachment repair and is characterized by the growth and contraction of cellular membranes within the vitreous cavity on both…
- Conditions
- Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy, Retinal Detachment
- Trial name
- FIXER (NCT04891991)
- Testing
- Intravitreal infliximab, Pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Retinal Detachment
Multi-electrocoagulation Retinectomy for Retinal Re-detachment in Silicone Oil Filled Eye
Retinal re-detachment in silicone oil filled eye, especially in the traumatic eye, is a complex retinal detachment with poor prognosis.
- Trial name
- NCT02201706
- Testing
- Multi-electrocoagulation retinectomy
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Sun Yat-sen University
Intraocular Pressure,, Postoperative Complications
Primary Vitrectomy for the Treatment of Retinal Detachment in Highly Myopic
Purpose: To assess the functional and anatomical outcome of primary vitrectomy without scleral buckling for rhegmatogenous retinal detachment (RRD) in highly myopic eyes with axial length over 30 mm.
- Trial name
- NCT01480505
- Testing
- Pars plana vitrectomy with gas tamponade
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pigment Epithelial Detachment
Lucentis to Treat Pigment Epithelial Detachment
Patients with Pigment Epithelial Detachments secondary to Age-Related Macular Degeneration (AMD) will receive intravitreal Lucentis monthly for 6 months in the hope of improving visual acuity from a baseline evaluation.
- Trial name
- NCT00841581
- Testing
- Ranibizumab
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Neovascular Age-related Macular Degeneration
Intravitreal Ranibizumab in Exudative Age-related Macular Degeneration With Posterior Vitreomacular Adhesion
The main objective is to determine the efficacy of intravitreal administration of Ranibizumab combined with intravitreous injection of expansile gas and induction of posterior vitreous detachment on best-corrected visual acuity…
- Trial name
- NCT01291121
- Testing
- Intravitreal expansile gas and ranibizumab injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Posterior Capsule Opacification, Retinal Degeneration
Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification
It has been hypothesized that potential effects of laser Nd: YAG laser posterior capsulotomy may affect macular pigment as well as choroidal thickness, macular thickness and anterior chamber parameters, so it was aimed to…
- Conditions
- Posterior Capsule Opacification, Retinal Degeneration, Retinal Detachment, Anterior Chamber Angle Congestion
- Trial name
- NCT03321253
- Testing
- Nd: YAG laser posterior capsulotomy
- Volunteers
- 38 people
- Sponsor
- Afyon Kocatepe University Hospital
Rhegmatogenous Retinal Detachment
Combined Laser-surgical Technology of RRD Treatment
Purpose: to assess the efficacy and safety of combined laser-surgical technology of RRD treatment
- Trial name
- NCT04403750
- Testing
- Combined laser-surgical technology of RRD treatment
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Retinal Detachment
Evolution of Aqueous Flare in Rhegmatogenous Retinal Detachments Treated With Gas or Silicone Oil Tamponade.
To examine and to compare the evolution of aqueous flare from presentation until the third postoperative month in a series of consecutive patients who underwent primary vitrectomy for rhegmatogenous retinal detachment (RRD), in 4…
- Trial name
- FLADESIL (NCT05053698)
- Testing
- Aqueous flare measurement
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Central Hospital, Nancy, France
Retinal Pigment Epithelial Detachment With Vascularization, Age Related Macular Degeneration
Iray for Vascularized Pigment Epithelial Detachment (VPED) Secondary to Age Related Macular Degeneration
This is a pilot, single-center, interventional clinical trial in which subjects will receive 16 Gy of IRay treatment and Lucentis, followed by Lucentis treatment as needed.
- Trial name
- NCT01521819
- Testing
- Iray, Lucentis
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Oraya Therapeutics, Inc.
Macular Degeneration, Wet Macular Degeneration
Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration
The purpose of the current study is to evaluate the ability of Eylea to induce a regression of PED height on patients previously extensively treated by Lucentis.
- Conditions
- Macular Degeneration, Wet Macular Degeneration, Retinal Degeneration, Retinal Diseases
- Trial name
- ARI2 (NCT02157077)
- Testing
- Aflibercept
- Where
- 9 sites in France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Rhegmatogenous Retinal Detachment
Treatment of Retinal Detachment in People Who Have Not Had Cataract Surgery With Vitrectomy vs Vitrectomy and Cataract Removal
Background and study aims The retina is the layer at the back of the eye that allows us to see. Sometimes, it can detach from the wall of the eye, causing a condition called rhegmatogenous retinal detachment (RRD), which leads to…
- Trial name
- COMBAT (NCT06997874)
- Testing
- Phacovitrectomy, Vitrectomy
- Where
- 30 sites in United Kingdom
- Volunteers
- 276 people
- Sponsor
- Queen's University, Belfast
Rhegmatogenous Retinal Detachment
hAM for Inferior RRD
The objective of the study is to evaluate the efficacy of using hAM patches over the retina to seal inferior retinal breaks. The researchers will evaluate whether hAM patch-assisted vitrectomy improves surgical success rate of…
- Trial name
- NCT07081945
- Testing
- hAM
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Ophthalmopathy
Evaluating Medium-chain Triglycerides as a Temporary Intraocular Tamponading Agent for Retinal Detachment
Background : Surgery is needed in order to flatten and position a detached retina onto the choroid, to allow sealing of the tears and to prevent or reverse vision loss.
- Trial name
- MCT (NCT03855462)
- Testing
- MCT oil injection
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Proliferative Diabetic Retinopathy, Tractional Retinal Detachment
Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy
To evaluate efficacy of different intravitreal Conbercept injection therapy in the treatment of severe proliferative diabetic retinopathy.
- Trial name
- NCT02816710
- Testing
- Conbercept
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Ruijin Hospital
Diabetic Retinopathy, Retinal Detachment
Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA)
The purpose of this study is to compare the amount of intraoperative intraocular bleeding during 23-gauge pars plana vitrectomy (PPV) for diabetic traction retinal detachment (TRD) with and without preoperative intravitreal…
- Trial name
- IBETRA (NCT00690768)
- Testing
- Bevacizumab, pars plana vitrectomy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
Comparing primary PPV with 360° endolaser photocoagulation with primary PPV with an encircling band for patients with RRDs.
- Conditions
- Rhegmatogenous Retinal Detachment, Primary Vitrectomy, Encircling Band, Endolaser Treatment
- Trial name
- NCT00757536
- Testing
- Encircling Band, Endolaser Photocoagulation
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery