Clinical trials: Treatment Of Obesity
Acute Lymphoblastic Leukemia
Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia
A single-arm, non-randomized four-month trial of the adapted family-based behavioral weight loss treatment (FBT) intervention will be conducted to evaluate its acceptability, feasibility, and preliminary indications of efficacy…
- Trial name
- NCT05410574
- Testing
- Family-based Behavioral Weight Loss Treatment
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Obesity & Overweight
Retrospective Evaluation of Sibutramine-Topiramate Therapy for Obesity in Real-World Outpatient Practice
This retrospective real-world cohort study aims to evaluate the effectiveness, safety, and tolerability of the combination of sibutramine and topiramate in the treatment of obesity and overweight associated with metabolic…
- Trial name
- SIBUTAMATE (NCT07588750)
- Testing
- Sibutramine + Topiramate
- Where
- Brazil
- Volunteers
- 278 people
- Sponsor
- Falquetomed
Obesity, Diabetes
Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea
The purpose of the study is to evaluate the efficacy and safety of ketogenic diet (KD) treatment of (i) obesity, (ii) type 2 diabetes mellitus and (iii) obstructive sleep apnea (OSA) in patients with obesity and Type 2 DM and in…
- Conditions
- Obesity, Diabetes, Obstructive Sleep Apnea
- Trial name
- KGDobesity (NCT02069197)
- Testing
- Ketogenic diet, Orlistat, Standardized diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mid-Atlantic Epilepsy and Sleep Center, LLC
Obesity, Weight Loss
Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment
Project ReLearn is testing the efficacy and cost-effectiveness of an Artificial Intelligence system for optimizing weight loss coaching.
- Trial name
- ReLearn (NCT05231824)
- Testing
- Standard Behavioral Weight Loss Treatment, AI-optimized Behavioral Weight Loss Treatment
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Oregon Research Institute
Pediatric Obesity
Qualitative Evaluation of Pediatric Obesity Therapeutic Education Programs
Obesity concerns almost the entire planet and is considered in France as a major public health issue: 17% of children are overweight and 4% obese.
- Trial name
- QUALIPOP (NCT06488235)
- Volunteers
- 32 people
- Sponsor
- University Hospital, Angers
Diabetes Mellitus, Type 2
Study to Determine the Utility of Novel Technologies and Biomarkers to Measure Human Response to Rosiglitazone Maleate
Insulin resistance (IR) is common in many metabolic disorders and predisposes an individual to Type 2 Diabetes Mellitus (T2DM), the Metabolic Syndrome and coronary atherosclerosis.
- Trial name
- NCT00551564
- Testing
- rosiglitazone maleate
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Food Addiction, Obesity, fMRI, Decision-making, Motivational Interviewing
FMRI of Dietary Decision-making in Food Addicted Participants Compared to Non-food Addicted Participants
Why in some situations can words soothe our cravings? This research proposal will test the power of self-generated reasons for behavioural change in food addiction, which concerns about three out of ten persons and causes major…
- Trial name
- MOTIVFOOD (NCT05101863)
- Testing
- Motivational interviewing
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Childhood Obesity, Metabolic Syndrome
Motivational Approach to Treat Childhood Obesity
The treatment of childhood obesity is challenging. Although dietary and physical activity recommendations are widely known, the willingness to change lifestyles within the family is not easy to be achieved.
- Conditions
- Childhood Obesity, Metabolic Syndrome, Body Composition
- Trial name
- OBEMAT20 (NCT03749200)
- Testing
- Obemat2.0 therapy, Regular practise in primary care
- Where
- 4 sites in Spain
- Volunteers
- 319 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Hypogonadism
Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment
The study is designed to answer the following questions: 1. What is the levels of visceral adiposity index and Triglycerides/HDL cholesterol ratio in hypogonadism? 2.
- Trial name
- NCT02111434
- Testing
- Testosterone
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Overweight, Obesity
Efficacy and Safety of IBI362 in Hypertensive Patients With Overweight/Obesity
A multicenter, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of IBI362 in participants with mild to moderate hypertension complicated by overweight/obesity who have not received…
- Conditions
- Overweight, Obesity, Hypertensive
- Trial name
- NCT07469800
- Testing
- IBI362
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Obesity
Study of VI-0521 Compared to Placebo in Treatment of Obesity in Adults
The purpose of this study is to evaluate the efficacy and safety of two doses of VI-0521 compared to placebo in treatment of obesity in an adult population with BMI ≥ 35.
- Trial name
- NCT00554216
- Testing
- VI-0521
- Where
- 5 sites in United States
- Volunteers
- 1,267 people
- Sponsor
- VIVUS LLC
Stroke, Obesity
Secondary Prevention of Stroke Through Non-drug Therapeutic Weight Reduction
SCENARIO is a trial to investigate the role of non-drug weight reduction in secondary prevention of stroke. It is a single-blinded, randomized, controlled multicentre trial with two arms.
- Trial name
- SCENARIO (NCT01721538)
- Testing
- Weight reduction program, Lecture on healthy nutrition
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Philipps University Marburg
Type 2 Diabetes
Roux-en-Y-Gastric Bypass vs. Lifestyle Modification and Medical Therapy in the Treatment of Type 2 Diabetes
The study is aimed to compare: Laparoscopic Roux-en-Y-Gastric Bypass (RYGB) + optimal medical therapy versus Intensive lifestyle modification and optimal medical therapy in the treatment of type 2 diabetes in…
- Trial name
- NCT01231308
- Testing
- Roux-en-Y-Gastric Bypass, Intensive lifestyle modification and Optimal medical Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Bariatric Surgery, Micronutrient Deficiencies
Supplementation After Bariatric Surgery
The aim of this study is to assess medication adherence to vitamin and mineral supplements after bariatric surgery and identify factors that may influence adherence.
- Conditions
- Bariatric Surgery, Micronutrient Deficiencies, Obesity
- Trial name
- NCT04412421
- Testing
- Gastric Bypass, Sleeve Gastrectomy
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Overweight and Obesity, Signs and Symptoms
Implications of Self-weighing During Weight Loss Treatment
This study aims to analyze the effectiveness of introducing behavioral elements in a weight loss program, in this case, comparing the difference between self-weighing versus not doing so.
- Conditions
- Overweight and Obesity, Signs and Symptoms, Behavior, Eating
- Trial name
- NCT04032249
- Testing
- Control Group (CG), Intervention Group (IG)
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
Type 2 Diabetes
Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics
A randomized clinical study to assess the efficacy of a high-protein diabetes specific formula (HPDSF) on lean muscle mass in overweight and obese patients with type 2 diabetes who are initiating treatment with incretin-mimetic…
- Trial name
- NCT07271043
- Testing
- protein supplement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joslin Diabetes Center
Primary Hypertension, Obesity
The Predictive Role of Urinary Proteomics in Blood Pressure Response of Obese Hypertensive Treated With Irbesartan or Eplerenone.
Despite the available means of treating primary arterial hypertension, the prevalence of hypertensive patients with inadequately controlled blood pressure levels, remains high.
- Trial name
- NCT06208072
- Testing
- Irbesartan 150mg, Eplerenone 25 mg
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Hippocration General Hospital
Healthy Participants
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese
A study in healthy male and female participants of non-childbearing and childbearing potential who have overweight or obesity
- Trial name
- NCT06132841
- Testing
- AZD6234
- Where
- 3 sites in United States, Japan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Obesity, Overweight
Response Evolution Chart
This study evaluates patient response to a motivation evolution chart for a medical-nutrition intervention as a continuation of a previous study: adherence to an overweight and obesity treatment available at…
- Conditions
- Obesity, Overweight, Motivation, Adherence, Patient
- Trial name
- NCT03484637
- Testing
- Lifestyle-medicine intervention
- Where
- Colombia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- BiomediKcal
Overweight, Obesity
A Study of How CagriSema Works on Appetite in People With Excess Body Weight
Part A: The study will look at participants appetite and energy intake and also look at the mechanisms of brain associated with appetite and food intake.
- Trial name
- NCT06267092
- Testing
- No treatment given, Cagrilintide and Semaglutide
- Where
- Germany
- Volunteers
- 164 people
- Sponsor
- Novo Nordisk A/S
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