Clinical trials: Treatment Of Obesity
Obesity, Weight Change, Body
Life Style Modification Medical and Surgical Management in Patients With Obesity
In this is an observational study, obese patients that administed and followed in endocrinology clinic of Marmara University Medical school hospital will follow for clinical and laboratory parameters prospectively for 5 years
- Conditions
- Obesity, Weight Change, Body, Obesity; Endocrine, Obesity, Metabolically Benign
- Trial name
- NCT04417582
- Testing
- bariatric surgey
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Marmara University
Obesity & Overweight, Overweight (BMI > 25)
Intervention Based on the Dietary Guidelines for the Brazilian Population for the Treatment of Overweight and Obesity
This clinical trial aims to evaluate how group-based food and nutrition education interventions, grounded in the recommendations of the Dietary Guidelines for the Brazilian Population, can improve participants' dietary quality…
- Trial name
- NCT07538362
- Testing
- Collective Intervention Based on the Dietary Guidelines for the Brazilian Population, Control Group: Individualized Care
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Obesity and Overweight
Impact of Bariatric Surgery and Liraglutide on Cognitive-Behavioral Markers of Long-Term Weight Loss in Obesity
The present research project aims to study the effects of bariatric surgery and liraglutide administration (in patients already selected for one of these procedures) on two cognitive-behavioral processes partially supported by…
- Trial name
- Balance (NCT06720246)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Obesity
Herb-partitioned Moxibustion Plus Lifestyle Modification Treatment for Simple Obesity
This study is designed as a three-dummy randomised controlled trial to evaluate the efficacy and safety of herb-partitioned moxibustion plus lifestyle modification treatment in patients with simple obesity.
- Trial name
- NCT04606680
- Testing
- Heat application at acupoints, Medicated plaster at acupoints, Herb-partitioned moxibustion at acupoints
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Depression
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients
To evaluate the efficacy of metformin as an adjunct therapy in improving depressive symptoms and metabolic markers in newly diagnosed obese depressed patients on standard antidepressant therapy.
- Trial name
- NCT06707012
- Testing
- Metformin Hydrochloride
- Where
- 2 sites in Pakistan
- Volunteers
- 140 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Sarcopenia, Body Composition
CT Body Composition as Predictor of Exercise Therapy Outcome in Peripheral Arterial Disease
Supervised exercise therapy (SET) is the recommended first treatment for patients with leg artery disease (peripheral arterial disease, PAD) causing pain when walking.
- Conditions
- Sarcopenia, Body Composition, Sarcopenic Obesity, Peripheral Arterial Disease
- Trial name
- COMPOSE-PAD (NCT07433309)
- Testing
- SET physiotherapy, CT scan
- Volunteers
- 128 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
NASH With Fibrosis, Diabete Type 2
Non-invasive Tests for Non-alcoholic Steato-hepatitis
The main objective is to study and validate a new approach for NASH and liver fibrosis diagnosis and personalized follow-up based on monocyte biomarkers and plasma metabolites.
- Conditions
- NASH With Fibrosis, Diabete Type 2, Obesity
- Trial name
- TEIRESEAS (NCT07502755)
- Testing
- Administration of Deuterated water
- Where
- Italy
- Volunteers
- 828 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Metabolic Syndrome
ENDOBARRIER® and Conventional Therapy in the Management of Metabolic Syndrome in Obese Patients
Obesity and metabolic syndrome (MS) are closely interrelated leading to increased mortality, mainly due to cardiovascular disease. In addition, some cancers are much higher when obesity is associated with metabolic syndrome.
- Trial name
- ENDOMETAB (NCT02297555)
- Testing
- ENDOBARRIER®
- Where
- 10 sites in France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Lille
Obesity, Diabetes
Effect of a Treatment of Lifestyle Changes on the Prevalence of Metabolic Syndrome and Body Weight in Mexican Women
The metabolic syndrome is a group of cardiometabolic risk factors that reflect a sedentary lifestyle and the excessive intake of food among the risk factors that comprise it are located the obesity, hyperglycemia, dyslipidemia…
- Conditions
- Obesity, Diabetes, High Blood Pressure, Dyslipidemia
- Trial name
- MPATPCDNC (NCT02247635)
- Testing
- Healthy lifestyle and adherence
- Where
- Mexico
- Volunteers
- 180 people
- Sponsor
- Mexican National Institute of Public Health
Obesity, Hypoandrogenism
Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism
Hypogonadism is a clinical condition that can be associated with obesity in man. Controversy exists regarding if its a condition that needs to be treated.
- Trial name
- NCT02380755
- Testing
- Clomiphene Citrate
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- University of Sao Paulo
Type 2 Diabetes
Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors
The overarching hypothesis of this study is that vildagliptin (vilda) as add on therapy to metformin (met) in Egyptian type 2 diabetic obese patient will produce an equal, if not better, glycemic control and will reduce…
- Trial name
- NCT07077525
- Testing
- Dapagliflozin + Metformin, Vildagliptin + Metformin
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Al-Azhar University
Spinal Cord Injury
Effects of Exercise in People With Paraplegia
This hypothesis-driven study will investigate effects of physical activity with or without a nutrient supplement known to increase body lean mass in adults with chronic paraplegia who have clusters of obesity and obesity-related…
- Trial name
- NCT01203150
- Testing
- Exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Miami
Obesity
Fecal Microbiota Transplantation for the Treatment of Obesity
This is a randomized controlled pilot study to assess the microbiological and clinical impacts of Fecal Microbiota Transplantation (FMT) in patients with obesity.
- Trial name
- FMT Obesity (NCT02741518)
- Testing
- Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Brigham and Women's Hospital
Obesity Hypoventilation Syndrome
The Obesity-hypoventilation Syndrome Study of Clinical Characteristics and Predictive Factors of Response to Treatment
Main objective: To describe clinical and functional characteristics of the obese hypoventilating patient; to study the relation between the obesity-hypoventilation syndrome (OHS) and the obstructive sleep apnea hypopnea syndrome…
- Trial name
- NCT00938977
- Testing
- CPAP, Bilevel Support Ventilation (Non-Invasive Ventilation)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Prader-Willi Syndrome
Cannabidiol Oral Solution for the Treatment of Patients With Prader-Willi Syndrome
The primary objective of this study is to assess the efficacy of cannabidiol oral solution on hyperphagia-related behavior in patients with Prader-Willi Syndrome (PWS).
- Trial name
- NCT02844933
- Testing
- Cannabidiol
- Where
- 7 sites in United States
- Volunteers
- 7 people
- Sponsor
- Radius Pharmaceuticals, Inc.
Insulin Resistance
Effect of 10-day Overnight Hypoxia Treatment on Whole Body Insulin Sensitivity (SLEEP HIGH Study)
The purpose of this study is to look at how a reduction in oxygen levels (hypoxia) influences insulin sensitivity and carbohydrate metabolism.
- Trial name
- SLEEP HIGH (NCT01872533)
- Testing
- Hypoxia Exposure
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Childhood
Lactoferrin Versus Iron Supplement in Irondeficiency Anemia and Weight Loss in Obese Children
The effect of lactoferrin versus iron supplement in treating iron deficiency anemia and helping weight loss in obese school age children
- Trial name
- NCT04014855
- Testing
- Iron Supplement
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Low Back Pain, Obesity
The Effect of Traction Forces in People With Obesity Suffering From Chronic Low Back Pain
The purpose of the research study is to assess the impact of traction forces on changes in systemic markers concentrations of spinal structure damage in people with obesity.
- Trial name
- NCT04507074
- Testing
- lumbar traction therapy
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Poznan University of Physical Education
Overweight and Obesity, Diabetes Mellitus, Type 2
Looking for Personalized Nutrition for Obesity/Type 2 Diabetes Mellitus Prevention
The objectives of this trial are to assess the effects of interactions between genetic factors and diet with various macronutrient intake on the metabolic disorders, obesity and type 2 diabetes risk, prevention, development and…
- Conditions
- Overweight and Obesity, Diabetes Mellitus, Type 2, Metabolic Syndrome, Genetic Predisposition
- Trial name
- NCT03792685
- Testing
- Normo-carbohydrate meal intake, High-carbohydrate meal intake, High-fat meal intake
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Weight Management, Treatment Of Obesity
A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight
Study of whether the investigational drug CE-326,597 improves glucose control and results in body weight loss in patients with type 2 diabetes
- Trial name
- NCT00542009
- Testing
- CE-326,597 100 mg QD, CE-326,597 50 mg QD, CE-326,597 25 mg QD
- Where
- 54 sites in United States, Bulgaria and 5 more
- Volunteers
- 252 people
- Sponsor
- Pfizer
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