Clinical trials: Treatment Of Obesity
Morbid Obesity
Lifestyleintervention for the Treatment of Severe Obesity
The overall purpose of this project is to study the acute, short- (≤ 1 year) and long- (> 1 year) term effects on body composition and psychological health after a 10 to 14-weeks comprehensive lifestyle modification program for…
- Trial name
- NCT01675713
- Testing
- Intensive lifestyle intervention
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- Norwegian School of Sport Sciences
Periodontal Diseases
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective
The goal of this observational study is to evaluate non-surgical periodontal treatment in women and men with periodontitis with and without obesity.
- Trial name
- NCT06261723
- Testing
- non-chirurgical periodontal treatment
- Where
- 2 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milagros Rocha Barajas
Obesity
A Study to Assess the Compliance and Impact on Weight of Kurbo, a Pediatric Centered Weight Loss App
Kurbo is a health and fitness app that is targeted toward the pediatric population. It utilizes games and activities to educate children about healthy eating, portion control/size and exercise.
- Trial name
- Kurbo (NCT02880254)
- Testing
- Kurbo, Personal Health Coach
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Obesity, Weight Loss
Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted…
- Conditions
- Obesity, Weight Loss, Weight Management, Dietary Intervention
- Trial name
- NCT06809166
- Testing
- Contrave, Diet Program
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- The Royal's Institute of Mental Health Research
Morbid Obesity, Perioperative Hemorrhage
Effect of Tranexamic Acid on Bleeding After Bariatric Surgery
Postoperative bleeding is an important complication of bariatric surgery and may lead to increased morbidity, prolonged hospitalization, and higher healthcare costs.
- Conditions
- Morbid Obesity, Perioperative Hemorrhage, Obesity, Tranexamic Acid
- Trial name
- TXA-BARI (NCT07754396)
- Where
- Greece
- Volunteers
- 140 people
- Sponsor
- G.Gennimatas General Hospital
Electric Stimulation Therapy, Obesity
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person…
- Conditions
- Electric Stimulation Therapy, Obesity, Weight Loss, Eating
- Trial name
- NCT00739362
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Extubation Failure
Postextubation High-flow Therapy vs Noninvasive Ventilation in Obese or at High-risk Patients
The main aim is to demonstrate whether reintubation rate is lower with preventive conditioned noninvasive ventilation (NIV) rather than with High-flow oxygen therapy (HFOT) in obese intermediate-risk patients and in high-risk…
- Trial name
- HINFOR (NCT04125342)
- Testing
- Preventive Conditioned NIV Therapy after planned extubation, Preventive HFOT after planned extubation
- Where
- 2 sites in Spain
- Volunteers
- 326 people
- Sponsor
- Hospital Virgen de la Salud
Periodontal Diseases
The Adjunctive Use of Melatonin Therapy in the Treatment of Obese Periodontitis Patients (Clinical and Immunological Study).
To evaluate the effect of adjunctive systemic administration of melatonin to mechanical non- surgical periodontal therapy in obese patients with periodontitis.
- Trial name
- NCT04788979
- Testing
- Melatonin 5Mg Oral Tablet
- Where
- Iraq
- Volunteers
- 80 people
- Sponsor
- University of Baghdad
Polycystic Ovary Syndrome (PCOS), Overweight
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Polycystic ovary syndrome (PCOS) is a health problem that affects one in 10 women of childbearing age, which is usually characterized by hormonal imbalance and metabolism problems such as hyperandrogenism and obesity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
- Trial name
- NCT03151005
- Testing
- Metformin-GLP-1 Receptor Agonist, Metformin-Oral Contraceptive(OC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xinqiao Hospital of Chongqing
Binge Eating Disorder, Cognitive Therapy/Methods
Psychological Treatment of Overweight Binge Eaters
Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on…
- Conditions
- Binge Eating Disorder, Cognitive Therapy/Methods, Mental Disorders/Epidemiology, Obesity/Epidemiology
- Trial name
- NCT01208272
- Testing
- Cognitive Behavioral Therapy (CBT), Interpersonal Therapy (IPT)
- Where
- 2 sites in United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Overweight, Obesity
The Additive Effect of Cognitive Behavioral Treatment (CBT) to Conventional Weight Loss Intervention Program for Young Adults With Intellectual Disabilities
In this randomized case control study we will evaluate the additive effect of psychological intervention, i.e CBT-cognitive behavioral treatment in a multi-strategy weight loss program composed of physical activity intervention…
- Conditions
- Overweight, Obesity, Learning Disability
- Trial name
- NCT01032369
- Testing
- Nutritional intervention and physical activity, Nutritional intervention, physical activity and behavioral treatment
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity
A Study to Determine the Effectiveness of a Self-regulation Program to Treat Pediatric Obesity
The objective of this study is to pilot test, evaluate and compare the effects of Cue Reactivity and Sensitivity Training (CRST) and Children's Appetite Awareness Training (CAAT) in 48 children aged 8-12 years old.
- Trial name
- ROC (NCT01442142)
- Testing
- CAAT: Appetite Awareness, CRST: Volcravo, Combined CAAT and CRST program
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hypoglycemia, Obesity, Morbid
The Effect of 'Medical Nutrition Therapy' on Post-bariatric Hypoglycemia 2-4 Years After Gastric Bypass Surgery
This is a pilot study to explore the effect of 'medical nutritional therapy' in patients diagnosed with post-bariatric hypoglycemia (PBH), 2-4 years after gastric bypass surgery.
- Trial name
- NCT05011682
- Testing
- Regular diet, 10-point nutrition plan
- Where
- Norway
- Volunteers
- 9 people
- Sponsor
- Helse Nord-Trøndelag HF
Obesity, Type 2 Diabetes
Rectal Short Chain Fatty Acids Combinations and Substrate and Energy Metabolism
Gut microbiota is being increasingly recognized as an important factor in fat distribution, insulin sensitivity and glucose and lipid metabolism.
- Trial name
- NCT01983046
- Testing
- Three different mixture of acetate, butyrate and propionate and palcebo
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenic Obesity, Acupuncture Treatment
The Effect of Acupuncture on Sarcopenia and Obesity in Patients With Sarcopenic Obesity.
Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as "a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, carrying a risk of adverse outcomes…
- Conditions
- Sarcopenic Obesity, Acupuncture Treatment, Exercise
- Trial name
- Sarcopenia (NCT07797140)
- Testing
- Diet and exercise, Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ayşe Ukbe Baykut
Obesity
Gastric Electrical Stimulation (GES) for the Treatment of Obesity
The purpose of this feasibility study is to provide safety data on the implantable Exilis gastric electrical stimulation (GES) system, to individually adjust stimulation parameters to levels that are comfortable for implanted…
- Trial name
- GES (NCT01823705)
- Testing
- Exilis Implantable Gastric Electrical Stimulation (GES)
- Where
- 4 sites in United States, Netherlands
- Volunteers
- 32 people
- Sponsor
- Medtronic Corporate Technologies and New Ventures
Deficiency, Vitamin D, Obesity
Dosage Calculation for Vitamin D Treatment
Severe vitamin D deficiency can be treated with oral loading doses of cholecalciferol. Our objective was to determine how to calculate the quantity of cholecalciferol needed for supplementation by single algorithm, usable on a…
- Trial name
- NCT02186106
- Testing
- Cholecalciferol
- Volunteers
- 31 people
- Sponsor
- Bispebjerg Hospital
Binge Eating Disorder
Treatment of Binge Eating Disorder in Obesity: Naltrexone/ Bupropion Combination Versus Placebo
This study will test the effectiveness of the combination of Naltrexone and Bupropion relative to placebo for reducing binge eating in persons with obesity and binge eating disorder.
- Trial name
- NCT02317744
- Testing
- Naltrexone and bupropion combination
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Yale University
Obesity
Alpha and Omega of Lifestyle Therapy
The study aims to investigate the effects of double-blinded, randomized placebo-controlled n3-fatty acid supplementation (1000 mg day-1) and 13 weeks of resistance training on muscle function/biology and systemic health in…
- Trial name
- Alpha&Omega (NCT04279951)
- Testing
- Resistance exercise, Omega-3
- Where
- Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Chronic Disease, Obesity
Active and Healthy Brotherhood: A Program for Chronic Disease Self-Management for Black Men
This study will test ways to improve health behaviors using an intervention that has been specially designed for African-American men.
- Conditions
- Chronic Disease, Obesity, Hypertension, Diabetes
- Trial name
- NCT02362737
- Testing
- Active and Healthy Brotherhood (AHB)
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Gramercy Research Group