Clinical trials: Treatment Of Obesity
Obesity, Obesity, Morbid
Deep Brain Stimulation for Morbid Obesity
This is an open-label, phase I pilot trial designed to evaluate the safety and feasibility of deep brain stimulation (DBS) for the treatment of refractory morbid obesity.
- Trial name
- NCT03650309
- Testing
- Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Obesity, Nutritional Deficiency
Comparison of Weight Loss and Nutritional Deficiency After One Anastomosis Gastric Bypass at 150, 170, and 200 cm From the Duodenojejunal Junction
This study is a randomized clinical trial comparing the effects of One Anastomosis Gastric Bypass performed at three different distances from the duodenojejunal junction-150 centimeters, 170 centimeters, and 200 centimeters-on…
- Conditions
- Obesity, Nutritional Deficiency, Type 2 Diabetes Mellitus (T2DM), Bariatric Surgery (Gastric Bypass)
- Trial name
- NCT06664099
- Testing
- One Anastomosis Gastric Bypass (150 cm from Duodenojejunal Junction), One Anastomosis Gastric Bypass (170 cm from Duodenojejunal Junction), One Anastomosis Gastric Bypass (200 cm from Duodenojejunal Junction)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Overweight and Obesity, Dyslipoproteinemia
Effect of Weight Management Programs on Cardiometabolic Risk Profile in Overweight Women
Aim of this prospective randomized study was to evaluate whether a diet with meal replacements can be as effective as a conventional energy-restricted modified diet on weight loss, body composition and cardiometabolic risk…
- Trial name
- FM-01 (NCT03109834)
- Testing
- Meal replacement (MR), Control (C), Verum
- Volunteers
- 105 people
- Sponsor
- Bonn Education Association for Dietetics r.A., Cologne, Germany
Pulmonary Atelectasis, Respiratory Tract Diseases
Influence of Different Physical Therapy Resources Application After Reduction Stomach Surgery
The aim of this study will be to investigate the effects of using physical therapy resources in the postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01872663
- Testing
- Continuous positive airway pressure, Incentive spirometry, Breath Stacking
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Obesity, Morbid, Metabolic Syndrome
Non-randomized Prospective Comparison Between SASI Bipartition and RYGB
The main aim of this project is to assess the safety and efficiency of the SASI Bipartition.
- Conditions
- Obesity, Morbid, Metabolic Syndrome, Bariatric Surgery Candidate, Postoperative Complications
- Trial name
- NCT04469712
- Testing
- SASI Bipartition, Gastric bypass
- Where
- Norway
- Volunteers
- 280 people
- Sponsor
- Aleris Hospital
Obesity, Polycystic Ovaries Syndrome
The Effect of Weight Loss on Anti-Müllerian Hormone Levels in Women With Polycystic Ovary Syndrome (PCOS)
The first aim of the investigators study, was to investigate the combined effect of diet,physical exercise and orlistat, for 24 weeks, on serum Anti-Müllerian Hormone (AMH) levels in obese women with polycystic ovary syndrome…
- Trial name
- NCT01475019
- Testing
- Orlistat, Sibutramine, Diet and physical exercise
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Healthy
Calanus Oil Supplementation and Maximal Oxygen Uptake
Copepod oil is extracted from the marine copepod Calanus finmarchicus, the dominant plankton species in the marine food web in the Norwegian Sea.
- Trial name
- NCT02908828
- Testing
- Calanus oil
- Where
- 2 sites in Norway
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Obesity, Overweight
Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
This study will look at how much cagrilintide helps people with overweight or obesity lower their body weight. Cagrilintide is a new investigational medicine. Doctors may not yet prescribe cagrilintide.
- Trial name
- RENEW 1 (NCT07220642)
- Testing
- Cagrilintide
- Where
- 40 sites in United States, Argentina and 8 more
- Volunteers
- 300 people
- Sponsor
- Novo Nordisk A/S
Obesity, Periodontal Diseases
Gingival Crevicular Fluid Levels of Prolactin Hormone in Obese Patients With Stage ii and Iii Periodontitis Before and After Non-surgical Periodontal Therapy
Obesity and periodontitis are among the most common chronic disorders affecting the world population, while Prolactin (PRL) is a neuroendocrine hormone that within the physiological range stimulates bone formation while mild to…
- Trial name
- NCT07571850
- Testing
- Obese patients with stage II and III periodontitis and non surgical peridontal therapy, obese patients with healthy periodontium with no intervention
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Obesity, Metabolic Syndrome
Integrated Traditional Chinese Medicine Day Care Program for Metabolic Syndrome
The goal of this study is to evaluate if a integrated tradtional Chinese medicine (TCM) program for improving metabolic syndrome is applicable.
- Conditions
- Obesity, Metabolic Syndrome, Dyslipidemias, Diabetes Mellitus
- Trial name
- NCT06703788
- Testing
- A fiixed combination of Chinese herbal medicine, Laser acupuncture
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Non-Alcoholic Fatty Liver Disease, Obesity
Alternate Day Fasting, Exercise, and NAFLD
Approximately 65% of obese individuals have non-alcoholic fatty liver disease (NAFLD), and this condition is strongly related to the development of insulin resistance and diabetes.
- Trial name
- NCT04004403
- Testing
- Alternate day fasting, Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Breast Cancer, Arthralgia
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer
Early stage hormone receptor positive breast cancer is typically treated with adjuvant endocrine therapy in order to decrease risk of breast cancer recurrence and to improve overall survival from the disease.
- Conditions
- Breast Cancer, Arthralgia, Obesity
- Trial name
- LOGRIBMET (NCT01896050)
- Testing
- anastrozole, letrozole, exemestane, Tamoxifen
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Michigan Rogel Cancer Center
Obesity, Dental Erosion
Salivary Function and Dental Changes During GLP-1 Therapy
People who use glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide and tirzepatide, may experience changes in their oral health.
- Conditions
- Obesity, Dental Erosion, Saliva Collection, Saliva Altered
- Trial name
- NCT07720466
- Testing
- Unstimulated Whole Saliva Collection, Salivary Analysis, Oral Examination and BEWE Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Breast Cancer
The Impact of Obesity and Obesity Treatments on Breast Cancer
The goal of this clinical research study is to find the highest tolerable dose of Avandamet that can be given in combination with exemestane to patients who are obese and postmenopausal with hormone-receptive-positive breast…
- Trial name
- NCT00933309
- Testing
- Exemestane, Avandamet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity
Efficacy of Polyglucosamine Long Term Treatment
The polyglucosamine, specification L112, is a medical device and in this clinical trial used for weight reduction in moderately obese participants following a long term treatment lasting 12 months.
- Trial name
- NCT02682277
- Testing
- polygucosamine
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Certmedica International GmbH
Binge Eating Disorder
Binge Eating Disorder Treatment Study
The main objective of the proposed study is to determine whether the effectiveness of a group therapy treatment for Binge Eating Disorder (BED) is improved and attrition reduced by optimally matching women with BED who have high…
- Trial name
- NCT00848367
- Testing
- Group Psychodynamic Interpersonal Psychotherapy
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Ottawa Hospital Research Institute
Binge Eating Disorder, Obesity
Craving, Binge Eating and Obesity
This research study is designed to look at the effectiveness of bupropion for reducing binge eating in overweight persons with binge eating problems.
- Trial name
- NCT00414167
- Testing
- bupropion
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Yale University
Childhood Obesity
Predictors of Success in an Intervention Program for the Treatment of Childhood Obesity
The child health and sports center, at the Meir Medical Center, runs for over 10 years an intervention program to treat obese children. The program includes physical activity, nutritional intervention and behavioral treatment.
- Trial name
- NCT01578863
- Testing
- Intervention program for obese children
- Where
- Israel
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Hypogonadotropic Hypogonadism
A Phase 2a Pharmacodynamic Study of TAK-448 in Participants With Hypogonadotropic Hypogonadism
The purpose of this study is to evaluate the effects on serum testosterone after 4 weeks of subcutaneous (SC) dose administration, with different doses and dosing frequencies of TAK-448 to overweight/obese males with…
- Trial name
- NCT02369796
- Testing
- TAK-448
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Takeda
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