Clinical trials: Treatment Of Obesity
Obstructive Sleep Apnoea, Obesity
Peripheral Vascular Function in Obstructive Sleep Apnoea
Peripheral vascular function is impaired in people with obstructive sleep apnoea who are untreated compared with age-, weight- and sex-matched healthy controls.
- Trial name
- NCT01619748
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Child Obesity
Enhancing Family Based Treatment of Childhood Obesity Through Social Networks
The purpose of this study is to develop a Social Network Engagement (SNE) Intervention that will be integrated into a standard treatment program for childhood overweight.
- Trial name
- CONNECT (NCT02206529)
- Testing
- Social Network Engagement+Std Treatment, Standard Treatment
- Volunteers
- 25 people
- Sponsor
- Kaiser Permanente
Heart Failure, Congestive, Metabolic Syndrome X
The Effect of Diet and Exercise in Heart Failure
A growing number of people in this country are overweight or obese. This is concerning as increasing weight has been shown to increase the risk of developing heart failure.
- Conditions
- Heart Failure, Congestive, Metabolic Syndrome X, Obesity
- Trial name
- LIMIT-HF (NCT00297154)
- Testing
- Lifestyle Modification (diet, exercise, and behavior)
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Obesity and Overweight
Metabolic Phenotyping for Personalized Obesity Therapy
This study aims to develop a simple, clinically applicable method for metabolic phenotyping to personalize obesity therapy in morbidly obese individuals.
- Trial name
- NCT06874270
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University Hospital Schleswig-Holstein
Obesity
Launch II: A Pilot Randomized Control Trial of a Clinic and Clinic Plus Home Intervention for Preschool Obesity
The objective of this project is to pilot test a behavioral intervention that includes a home visit component compared to a clinic only and standard of care for the treatment of obesity in preschool age children.
- Trial name
- NCT01419951
- Testing
- Clinic + Home Behavioral Intervention, Pediatrician Counseling, Clinic Only Behavioral Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Loss of Control Eating
Loss of Control Eating Following Weight Loss Surgery
This study will test the effectiveness of two distinct behavioral treatments for loss of control eating following bariatric surgery: 1. Behavioral Weight Loss Treatment 2.
- Trial name
- NCT02259322
- Testing
- Standard-of-Care, Behavioral Weight Loss Treatment, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Obesity
Effects of Group Vs. Home-Based Combined Exercise-Diet Program In Childhood Obesity: A Randomised Controlled Trial
The aim of this study was to compare the effect of a hospital group-based vs. home-based combined exercise-diet program for the treatment of childhood obesity.
- Trial name
- NCT01503281
- Testing
- Circuit training
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Morbid Obesity, Sports Physical Therapy
Nonresponders by the Session Order Factor
Concurrent training (CT, characterised by the inclusion of two exercise modalities), is recognised to improve metabolic syndrome (MetS) markers, but little is known about order session effect on interindividual variability.
- Trial name
- NCT04932642
- Testing
- HIIT+RT experimental group, RT+HIIT experimental group
- Where
- Chile
- Volunteers
- 43 people
- Sponsor
- Cristian Alvarez
Overweight and Obesity, Diabetes
EndoBarrier TM Gastrointestinal Liner Diabetes Trial
The management of obesity is challenging and obesity surgery is by far the most effective treatment currently available. Recent medical research indicates that it also improves the management of blood glucose levels in people…
- Trial name
- EndoBarrier (NCT02459561)
- Testing
- EndoBarrier TM Gastrointestinal Liner, Best Medical Care
- Where
- United Kingdom
- Volunteers
- 170 people
- Sponsor
- Imperial College London
Diabetes Mellitus, Obesity
Surgery Treatment of Type 2 Diabetes Mellitus Patients With Grade 1 Obesity and Overweight
This study evaluate the Duodenal Ileal Interposition with Sleeve Gastrectomy for Type 2 Diabetes Mellitus in grade 1 obesity and overweight patients.
- Conditions
- Diabetes Mellitus, Obesity, Overweight
- Trial name
- NCT03333642
- Testing
- Duodenal Ileal Interposition with Sleeve Gastrectomy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Federal de Bonsucesso
HIV Infections, Obesity
Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain
The purpose of this research study is to understand why certain HIV medication regimens (called anti-retroviral or ARV medications) cause more weight gain than others.
- Trial name
- NCT05463783
- Testing
- Biktarvy, Symtuza
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- East Carolina University
Obesity, Insulin Resistance
Probiotics on Body Composition and Insulin Resistance in Patients With Obesity and Its Association With Gut Microbiota
This study aims to evaluate the modifications in body composition and insulin resistance state in patients with grade II and III obesity included in an interventional lifestyle changes program and treated with probiotics (1 x…
- Conditions
- Obesity, Insulin Resistance, Microbial Colonization
- Trial name
- NCT04086173
- Testing
- Probiotics
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Obesity
Auricular Acupuncture in the Treatment of Obesity
Male and female DoD beneficiaries ages 18 years or older, who are referred for a standard of care weight loss intervention for treatment of obesity will be recruited.
- Trial name
- AcupObesity (NCT02269371)
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Mike O'Callaghan Military Hospital
Gout, Arthritis, Obesity
Weight Loss for Obese Individuals With Gout
This study evaluates effect of weight loss in a group of obese patients with gouty arthritis. The study is a randomised group trial where half the patients receive intensive weight loss in the form of meal replacement from…
- Trial name
- NCT03664167
- Testing
- intensive weight loss diet, with Cambridge weightplan products, and visits to a dietician.
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Henning Bliddal
Metabolic Syndrome X
Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
The Metabolic Syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers the disease. Resveratrol is a substance found in many plants, including grapes, nuts and wine, but it's also found in…
- Trial name
- NCT02114892
- Testing
- Resveratrol
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Diabetes Mellitus Type 2, Dyslipidemia
Omentectomy for the Treatment of Diabetes Mellitus Type 2
The purpose of this study is to determine whether laparoscopic removal of the omentum (thin layer of fat inside the abdomen) will significantly improve insulin resistance in patients with non-insulin dependent type 2 diabetes…
- Conditions
- Diabetes Mellitus Type 2, Dyslipidemia, Hypercholesterolemia, Obesity
- Trial name
- NCT00270439
- Testing
- removal of omentum
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University
Obesity
Investigation of a New Diet for the Treatment of Obesity in the NHS
Over one in four adults living in the UK is living with obesity. Obesity is associated with health complications including type 2 diabetes, heart disease and depression.
- Trial name
- NCT05249439
- Testing
- I-SatPro weight loss programme, Tier 3 weight loss programme
- Volunteers
- 21 people
- Sponsor
- Imperial College London
Mental Disorders, Schizophrenia
Web-Based Weight Management for Individuals With Mental Illness
Obesity and physical inactivity have become serious problems for individuals with mental illness, resulting in increased rates of chronic disease, premature death, and substantial health care costs.
- Conditions
- Mental Disorders, Schizophrenia, Affective Disorders, Psychotic, Overweight
- Trial name
- eWellness (NCT01324973)
- Testing
- eWellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Bardet-Biedl Syndrome
The Effect of GLP1 Agonists on Weight Loss in BBS Cohort in the UK
The goal of this observational study is to learn about the long-term effects of GLP1 agonists (weight loss jab, including Mounjaro) in patients with Bardet-Biedl Syndrome (BBS) who take GLP1 agonists to treat high body weight.
- Trial name
- NCT07602803
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- The Queen Elizabeth Hospital
Contraception
US Ovulation Inhibition Study in Obese Women
Birth Control Patch Study
- Trial name
- NCT00873483
- Testing
- Ethinylestradiol/Gestodene (BAY86-5016)
- Where
- 6 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Bayer
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