Clinical trials: Treatment Of Obesity
Obesity & Overweight, GLP - 1
A Study on Ubiquinol on Fatigue and Muscle Strength in Healthy Adults Taking GLP-1 Agonists
The goal of this clinical trial is to learn if a daily ubiquinol supplement can reduce fatigue and help maintain muscle strength in adults aged 30-65 who are taking a GLP-1 weight loss medication (Wegovy® or Mounjaro®).
- Conditions
- Obesity & Overweight, GLP - 1, Fatigue Severity Scale, Ubiquinol
- Trial name
- Project Zest (NCT07789106)
- Testing
- Ubiquinol 100 MG Oral Capsule
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- StudySetGo
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Obesity
Low Carbohydrates in Obese Adolescents
A three arms open,randomized interventional study in order to compare the impact of low carbohydrate diets with different protein and fat ratios versus a standard balanced diet on BMI and metabolic parameters in obese…
- Trial name
- NCT00575900
- Testing
- dietary intervention
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Systemic Hypertension, Obesity
GAstric Bypass to Treat obEse Patients With steAdy hYpertension
Phase 3, unicentric, randomized clinical trial, with allocation concealment and intention-to-treat analysis to evaluate the efficacy of videolaparoscopic Roux-en-Y Gastroplasty to decrease the prescription of antihypertensive…
- Trial name
- GATEWAY (NCT01784848)
- Testing
- Laparoscopic Roux-en-Y gastric bypass (LRYGB), Clinical treatment
- Where
- 3 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital do Coracao
Gastroesophageal Reflux
The Detection of Barrett's Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy
Severe Gastroesophageal reflux disease (GERD) leading to a chronic aggression of esophagus mucosa, called Barrett's esophagus is a main complication of Sleeve gastrectomy for morbid obesity.
- Trial name
- Refleeve (NCT03596411)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Childhood Obesity, mHealth
Family Intervention for Treatment of Obesity With Digi-physical Support
Obesity in childhood is a global public health problem which continues to increase. It is associated with type 2 diabetes, high blood pressure, certain types of cancer, decreased psycho-social health and early mortality, among…
- Conditions
- Childhood Obesity, mHealth, Personalized Medicine
- Trial name
- NCT06236906
- Testing
- Device supported behavioural treatment
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Overweight or Obesity; Type 2 Diabetes, Weight Loss Maintenance
AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in Adults With Type 2 Diabetes (AIM-MAINTAIN)
This is a randomized controlled trial to compare the effect of AI-assisted multi-domain lifestyle and continued tirzepatide on body weight loss maintenance.
- Trial name
- NCT07555730
- Testing
- AI assisted multi-domain lifestyle intervention, Tirzepatide
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Huazhong University of Science and Technology
Endometrial Cancer, Endometrial Cancer Stage I
SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus Standard Surgery in Patients With Obesity and Early-Stage Endometrial Cancer
SHAPE-ENDO is a single-center, open-label, pilot randomized clinical trial conducted at Hospital Universitari de Bellvitge in Barcelona, Spain.
- Conditions
- Endometrial Cancer, Endometrial Cancer Stage I, Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I, Atypical Endometrial Hyperplasia
- Trial name
- SHAPE-ENDO (NCT07462663)
- Testing
- GLP-1 Receptor Agonist, Levonorgestrel IUD (Lng-IUD), Oral Progestins
- Volunteers
- 80 people
- Sponsor
- Hospital Universitari de Bellvitge
Psoriatic Arthritis (PsA), Obesity & Overweight
Combination of Biologic and Anti-obesity Therapies in Psoriatic Arthritis
This is a trial to find out how weight loss (achieved by the use of tirzepatide) or ixekizumab treatment affects the characteristics of skin, joint and fat tissues in patients with Psoriatic Arthritis, Psoriasis and…
- Trial name
- COMBAT-PsA (NCT07443956)
- Testing
- Ixekizumab, Tirzepatide
- Where
- 4 sites in United Kingdom
- Volunteers
- 45 people
- Sponsor
- NHS Greater Glasgow and Clyde
Obesity, Primary
A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm
Cross-over arm of the pilot study evaluating a treatment for obesity.
- Trial name
- NCT05939973
- Testing
- g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- USGI Medical
Metabolic Syndrome (MetS), Hypertension (HTN)
Metabolic Surgery for Metabolic Syndrome
This study is designed to understand how bariatric surgery affects patients with metabolic syndrome over both the short and long term.
- Conditions
- Metabolic Syndrome (MetS), Hypertension (HTN), Obesity, T2
- Trial name
- NCT07183137
- Where
- 3 sites in China
- Volunteers
- 1,581 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Gestational Diabetes, Metformin
Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women
Gestational diabetes (GD) is defined by a hyperglycemia discovered during pregnancy, leading to fetal and maternal complications which may be prevented by reaching very strict glycaemia targets.
- Conditions
- Gestational Diabetes, Metformin, Treatment, Oxidative Stress
- Trial name
- NCT01756105
- Testing
- Metformin, Rapid acting analog insulin Intermediate acting NPH Insulin
- Where
- 5 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Strasbourg, France
Obesity
Relation of Blood-boron Levels With Body Mass Index
According to our experimental experiences w hypothesized that blood boron levels may be corralated to body mass index.
- Trial name
- NCT01400061
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SB Istanbul Education and Research Hospital
Obesity
Effectiveness of Cognitive Behavioral Therapy vs. Prescriptive Diet in Short and Medium-term Control of Body Weight
Comparison between different treatments of obesity in the short and medium term: prescriptive diet therapy compared to to cognitive-behavioral approach in the treatment of obesity according to the method of clinical trial.
- Trial name
- NCT01686854
- Testing
- Cognitive Behavioral (B), Prescriptive Diet (A)
- Where
- Italy
- Volunteers
- 163 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Obesity
Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic
Research purpose: The purpose of this pilot study is to assess obese clients for two phenotypes, those testing positive and those testing negative for Food Addiction (FA) (Yale Food Addiction Scale, YFAS) and determining the…
- Trial name
- NCT03431831
- Testing
- Intervention Control, Counselling, Contrave
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Obesity
The ACE Follow-up Study
The Articulating Circular Endoscopic (ACE) Stapler is an investigational system using endoscopic guidance to trans-orally place plications in the stomach in obese subjects to reduce volume and expansion of the fundus and greater…
- Trial name
- NCT01429194
- Testing
- ACE Stapler
- Where
- 6 sites in Argentina, Canada and 2 more
- Volunteers
- 69 people
- Sponsor
- Boston Scientific Corporation
Obese Patients
Impact of Thoracic Duct Ligation on Postoperative Weight Reduction in Obese Patients Receiving Minimally Invasive Lung Surgery: A Clinical Investigation
This clinical trial aims to investigate whether thoracic duct ligation (TDL) can improve obesity and lipid metabolism. The primary questions it seeks to answer are: Whether thoracic duct ligation can improve BMI and lipid…
- Trial name
- NCT06995599
- Testing
- Thoracic Duct Ligation (TDL)
- Volunteers
- 16 people
- Sponsor
- Yongxin Zhou
Hypogonadism, Obesity
Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.
The purpose of this study was to compare the effects of liraglutide and testosterone replacement therapy on features of hypogonadism and weight loss in obese men with persistent features of hypogonadism after unsuccessful…
- Trial name
- NCT03619330
- Testing
- liraglutide, Testosterone
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Overweight and Obesity
Tailored Lifestyle Intervention in Obese Adults Within Primary Care Practice - Choose to Lose
The primary objective of the study is to evaluate the effectiveness of tailored lifestyle intervention in primary care by comparing changes in the primary measure of weight and body mass index (BMI) and secondarily: physical…
- Trial name
- CTL (NCT01542671)
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Obesity and Obesity-related Medical Conditions, Obesity and Overweight
REvision of VSG with Ablation of the Mucosa Procedure
The purpose of this study is to evaluate the feasibility, safety, and tolerability of endoscopic selective gastric mucosal ablation (GMA) using argon plasma coagulation after sleeve gastrectomy.
- Conditions
- Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Obesity Prevention, Obesity Recidivism
- Trial name
- REVAMP (NCT06671119)
- Testing
- Gastric Mucosal Ablation (GMA)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Dr. Christopher McGowan
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