Clinical trials: Treatment Of Obesity
Type 2 Diabetes, Obesity
GENETIC VARIABILITY TO GLP1 TREATMENT
The goal of this retrospective study is to assess whether a selection of genetic variants may allow us to identify individuals who will have a satisfactory response after GLP-1 treatment in terms of weight loss, sugar level…
- Trial name
- GLP1 treatment (NCT06298799)
- Testing
- DNA Sequencing and Analysis, differential expression analysis with RNA-sequencing (RNA seq) experiments
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- GENGE
Obesity, Morbid
Bariatric Surgery in Children.
Rationale: In the Western world overweight and obesity is an increasing problem both in adults and in children. In youth, it is associated with early death and a number of co-morbidities including metabolic and endocrine changes…
- Trial name
- BASIC (NCT01172899)
- Testing
- laparoscopic adjustable gastric band, Combined life style interventions
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Obesity, Type 2 Diabetes
Ability of Almonds to Improve Nutrition During GLP-1 Treatment
This 8-week randomized controlled pilot trial is to test the hypothesis that, compared to a Usual Diet control group, almond intake will increase vitamin E (alpha-tocopherol) levels in the blood and improve diet quality (Healthy…
- Trial name
- NCT07796204
- Testing
- Almond Diet
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Pennington Biomedical Research Center
Obesity, Vitamin D Deficiency
Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
As the use of bariatric surgery for treatment of extreme obesity adults continues to rise, clinicians must be aware of pre-existing nutritional deficiencies in overweight and obese patients.
- Trial name
- NCT01385098
- Testing
- Vitamin D3 and Calcium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vadim Sherman, MD
Weight Loss, Morbid Obesity
Maintenance Programme After Weight Loss
The aim of this study is to compare a weight reduction programme with and without a maintenance programme in patients with severe obesity.
- Trial name
- NCT00590655
- Testing
- weight loss programme with maintenance programme, weight loss programme
- Where
- Finland
- Volunteers
- 201 people
- Sponsor
- University of Helsinki
Obesity, High Blood Pressure
Metabolic Syndrome Diagnosis and Treatment for Adults of Low Socioeconomic Status Communities
The objective of this study is to evaluate the effect of a healthy-habits intervention tailored to the cultural, economical and social context of the target population in cardiometabolic parameters, for a population with no…
- Conditions
- Obesity, High Blood Pressure, Hyperglycemia, Dyslipidemia
- Trial name
- PrEVEnTYCM (NCT02459249)
- Testing
- Healthy Lifestyle
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Mexican National Institute of Public Health
Hypertension
Losartan and Simvastatin in Hypertensive Obeses With Liver Steatosis
Angiotensin II has been proposed as a lipid metabolism regulator. It is known that adipocytes secrete a variety of protein, such as TNFα, plasminogen activator inhibitor (PAI)-1, leptin, resistin and adiponectin; these proteins…
- Trial name
- NCT00669435
- Testing
- Losartan + Simvastatin, Amlodipine + Simvastatin
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University of Pavia
Liver Insufficiency, Kidney Failure, Chronic
Quantification of Drugs and Their Degradation Products
The study includes two study parts in which blood is collected from the patients. Study part A (observational study, already received positive ethics committee vote; Our sign: 12-330): Use of blood samples gathered during routine…
- Conditions
- Liver Insufficiency, Kidney Failure, Chronic, Obesity, Pregnancy
- Trial name
- NCT01828372
- Testing
- additional blood withdrawals
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University of Cologne
Childhood Obesity
Effect of Polysaccharide-based Complex Administration on the Gut Microbiome and Cardio-Metabolic Profile in Children With Obesity and Metabolic Syndrome.
Childhood obesity is a growing public health concern and is associated with long-term health issues. Changing lifestyle habits, especially improving diet and maintaining these changes over time, can be challenging for children…
- Trial name
- Polymets (NCT07321184)
- Testing
- Polysaccharide-based complex
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Milan
Type 1 Diabetes Mellitus, Overweight and Obesity
Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity
This study is a 2-arm, double blinded, randomised clinical trial where 40 participants will be assigned 1:1 to insulin treatment alone (control) or insulin treatment and tirzepatide treatment for 32 weeks.
- Trial name
- TZP-T1D (NCT06180616)
- Testing
- Tirzepatide
- Volunteers
- 40 people
- Sponsor
- Royal North Shore Hospital
Breast Cancer
Evaluation of a Physical Activity Program in Overweight Breast Cancer Patients
Patients diagnosed with breast cancer generally have a fairly well prognosis with estimated average survival rates of 73% and five year survival rates of 89% in developed countries.
- Trial name
- I-Move (NCT02424292)
- Testing
- Physical activity
- Where
- 4 sites in Netherlands
- Volunteers
- 141 people
- Sponsor
- University Medical Center Groningen
Breast Cancer, Obesity
Effects of Mediterranean Diet Based Intervention in Breast Cancer Patients
The purpose of this randomized clinical trial is to examine the effects of Mediterranean diet based intervention on inflammation and metabolic risk factors in overweight or obese postmenopausal women with breast cancer receiving…
- Trial name
- NCT04045392
- Testing
- Mediterranean diet
- Volunteers
- 78 people
- Sponsor
- Gangnam Severance Hospital
Insulin Resistance
Vitamin D Supplementation and Glycemic Outcomes
The investigators examined the effect of vitamin D supplementation on glucose homeostasis and metabolic markers in healthy normal weight and overweight young subjects and healthy normal-weight and overweight elderly subjects…
- Trial name
- NCT02942732
- Testing
- cholecalciferol (Euro-Pharm International, Canada)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université d'Auvergne
Lumbar Disc Herniation, Radiculopathy Lumbar
The Effect of Subcutaneous Fat Tissue Thickness on Lumbar Transforaminal Epidural Steroid Injection Treatment Success
Nerve compression due to lumbar disc herniation and related radicular pain is a very common condition when the lifetime prevalence is considered.
- Conditions
- Lumbar Disc Herniation, Radiculopathy Lumbar, Obesity
- Trial name
- NCT05556538
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Marmara University
Obesity
Intermittent Hypoxia-hyperoxia Therapy in Obese Patients (IHHTOP)
Obesity represents the excessive or abnormal accumulation of adipose tissue in the body, which affects health through its association with the risk of developing diabetes mellitus, cardiovascular and pulmonary diseases and…
- Trial name
- (IHHTOP) (NCT06451601)
- Testing
- Intermittent hypoxia-hyperoxia therapy
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Balnear and Rehabilitation Sanatorium Techirghiol
Obesity, Abdominal Obesity
Study of Safety and Efficacy of a Probiotic and Postbiotic in Overweight Individuals
Investigate the effect of a probiotic (live bacteria) and postbiotic (heat-treated bacteria) strains in overweight individuals.
- Trial name
- KOBI (NCT05428137)
- Testing
- Probiotic, Postbiotic
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Obesity
National Registry of Obesity Treatment by Endosleeve
Obesity and overweight have emerged as public health problems of a pandemic nature, significantly reducing the life expectancy of those affected.
- Trial name
- NCT06657339
- Testing
- Therapeutic endoscopy endosleeve using a gastric suturing device (OverStitch™/Endomina™)
- Volunteers
- 354 people
- Sponsor
- Société Française d'Endoscopie Digestive
Gamification in Health Education, Health Education
Study on the Effect of a Gamified Health Education Programme on Primary School Children
This randomised study evaluates the effectiveness of Health Education through a Gamified Health Programme on diet, sedentary behaviour and daily physical activity in primary school children.
- Trial name
- BELLOTEX-SALUD (NCT07276412)
- Testing
- Intervention - A, Intervention - B, Intervention - C
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Acupuncture
Efficacy of Abdominal Catgut Embedding Combined With Auricular Acupressure Therapy for Obese Patients
Objective: obesity is an important risk factor of chronic diseases, which not only threatens people's health, but also an important topic of public health.
- Trial name
- NCT06133205
- Testing
- Catgut Embedding at acupoints
- Where
- Taiwan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Obesity, Non-insulin-dependent Diabetes Mellitus
Effects of HBO Therapy on Muscular Insulin Resistence in Type 2 Diabetes
Hyperbaric oxygen therapy (HBO) is applied for several diseases. The effect on insulin sensitivity is yet unknown. Hypothesis: HBO therapy improves insulin sensitivity in patients.
- Trial name
- NCT01472328
- Testing
- HBO therapy, Hyperbaric room air
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.