Clinical trials: Treatment Of Obesity
Fibromyalgia (FM)
Dietary Strategies for the Treatment of Fibromyalgia in Overweight and Obese Patients
Spontaneous, non-sponsored, interventional, controlled, randomized, parallel-arm clinical study. Primary objective To assess the impact of specific dietary approaches (ketogenic diet, Mediterranean diet, or Mediterranean diet…
- Trial name
- FIBRODIET (NCT07517757)
- Testing
- Very Low-Calorie Ketogenic Diet, Mediterranean diet, Mediterranean diet enriched by GABA-producing probiotic
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Universita degli Studi di Genova
Stress, Childhood Obesity
Healing Experiences of Adversity Among Latinos (HEALthy4You)
Healing Experiences of Adversity Among Latinos (HEALthy4You) is a project funded by the California Initiative for the Advancement of Precision Medicine ("Advancing a Precision Population Health Approach to ACEs to Reduce Health…
- Trial name
- NCT05676281
- Testing
- Healthy Together (Control), Healthy Together + Promotora Support, Healthy Together + Parenting Training
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pulmonary Atelectasis, Respiratory Tract Diseases
Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01786681
- Testing
- Positive pressure
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Obesity & Overweight
Two-Year Weight Loss With GLP-1 Medications Compared With Sleeve Gastrectomy in Adults With Obesity
This observational study will compare weight loss over two years in adults receiving GLP-1 receptor agonist medications with weight loss in adults who previously underwent laparoscopic sleeve gastrectomy, an operation that…
- Trial name
- GLP-BARI-VAN (NCT07901777)
- Testing
- GLP-1 Receptor Agonist Therapy, Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Yuzuncu Yil University
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients
Type 2 Diabetes Mellitus (T2DM) is a progressive metabolic disease, often compounded by obesity, that leads to serious long-term health complications.
- Trial name
- NCT07728318
- Testing
- Tirzepatide + Standard Therapy (Intervention Group), Standard Oral Antidiabetic Drugs (OADs)
- Volunteers
- 52 people
- Sponsor
- Akhtar Saeed Medical and Dental College
Obese Hypogonadotropic Hypogonadism
Safety and Efficacy of BGS649 in Obese, Hypogonadotropic Hypogonadal Men
This study is designed as a 2-part study, with Part 1 being open-label to best determine the appropriate dose levels to use in Part 2, which has a randomized, double-blind, placebo controlled design.
- Trial name
- OHH (NCT01200862)
- Testing
- Investigational new drug company code: BGS649
- Where
- 5 sites in United States, Canada
- Volunteers
- 29 people
- Sponsor
- Mereo BioPharma
Obesity
For the Health of Our Children--Clinic Based Treatment of Childhood Obesity
Childhood obesity is a major public health problem in the U.S. Currently approximately one in three children is considered overweight or obese. Most overweight children grow to become overweight adults.
- Trial name
- NCT01625910
- Testing
- Behavioral counseling
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Binge Eating, Obesity
Feasibility of a Digital Therapeutic for Adults With Binge Eating and Obesity
The primary objective of this study is to test the feasibility of a digital therapeutic to address comorbid binge eating and obesity in adults.
- Trial name
- NCT06454123
- Testing
- OTX-401
- Volunteers
- 30 people
- Sponsor
- Oui Therapeutics, Inc.
Labor, Induced, Obesity
Misoprostol for Induction of Labor in Obese Women: Comparison Between 25 and 50 mcg Oral Administration
In recent decades, obesity has become a prevalent issue in Portugal, with 38.6% and 13.8% of the population being overweight or obese, respectively.
- Conditions
- Labor, Induced, Obesity, Pregnancy, Cesarean Section
- Trial name
- NCT05857059
- Testing
- Misoprostol 25 mcg, Misoprostol 50 mcg
- Where
- Portugal
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Type 2 Diabetes, Overweight
Lifestyle Intervention for Treatment of Diabetes
This study is evaluating two approaches to improving the control blood sugar, and other risk factors for heart disease in overweight and obese adults with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Overweight, Obesity
- Trial name
- LIFTDiabetes (NCT01806727)
- Testing
- Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Wake Forest University
Morbid Obesity, Bariatric Surgery
Registry on Obesity Surgery in Adolescents
While bariatric surgery is established as a safe and effective alternative with well-defined risks for severely obese adults, little has been published on its use in children.
- Conditions
- Morbid Obesity, Bariatric Surgery, Adolescent Obesity
- Trial name
- ROSA (NCT03203161)
- Testing
- bariatric surgery
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Queen Fabiola Children's University Hospital
Overweight and/or Obesity, Metabolic Syndrome
iWAIST Trial: ERCG (Endoscopic Radial Compression Gastroplasty) +Optimized Lifestyle Intervention (OLI) vs Sham + OLI for Weight Loss
This randomized, sham-controlled trial evaluates the efficacy and safety of ERCG plus optimized lifestyle intervention compared with sham procedure plus optimized lifestyle intervention in Chinese adults with overweight…
- Conditions
- Overweight and/or Obesity, Metabolic Syndrome, Nonalcoholic Fatty Liver Disease
- Trial name
- iWAIST-RCT (NCT07237750)
- Testing
- Endoscopic Radial Compression Gastroplasty, Optimized Lifestyle Intervention (OLI)
- Where
- 2 sites in China
- Volunteers
- 216 people
- Sponsor
- Liu Yan
Obesity, Diabetes Mellitus, Type 2
A Study of the Efficacy and Safety of Topiramate in the Treatment fo Obese, Type 2 Diabetic Patients Treated With Metformin
The purpose of this study is to compare the efficacy (in terms of weight and hemoglobin type A1c [HbA1c]) and safety of topiramate (96 milligrams[mg] or 192 mg daily) with placebo in the treatment of obesity in Type 2 diabetic…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset
- Trial name
- NCT00231660
- Testing
- topiramate
- Volunteers
- 211 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Obesity, Overweight
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
Background: Sticking to a diet plan can be difficult, but is important for many different health reasons. Some people seem to have a harder time following and sticking to a diet plan than others.
- Trial name
- NCT01862796
- Testing
- Underfeeding diet, Weight maintaining diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Treatment of Obesity
A Post-Market Surveillance Study of Using the g-Cath EZ for Treating Obesity
This is a multi-center, prospective study evaluating a treatment for obesity.
- Trial name
- NCT03721731
- Testing
- Obesity treatment with a Plication device
- Where
- 2 sites in Spain
- Volunteers
- 39 people
- Sponsor
- USGI Medical
Obesity/Overweight
Efficacy and Safety of ALT-801 in the Treatment of Obesity
This study will evaluate the efficacy and safety of ALT-801 once-weekly versus placebo as an adjunct to a reduced-calorie diet and increased physical activity in patients with obesity/overweight.
- Trial name
- NCT05295875
- Testing
- ALT-801
- Where
- 31 sites in United States
- Volunteers
- 391 people
- Sponsor
- Altimmune, Inc.
Psoriasis
A Single-Center, Prospective, Pilot Study to Compare the Effect of Diet in Overweight or Obese Patients With Psoriasis on Light Therapy
Weight loss may help psoriasis. Phototherapy helps psoriasis. Combining the two treatments may help even more. Determining if a high protein diet vs a low protein diet results in improving psoriais may help lead to future dietary…
- Trial name
- NCT02193919
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bagel, Jerry, M.D.
Diabetes Mellitus Type 2
A Study of Taspoglutide Versus Placebo for the Treatment of Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy
This 2 arm study will assess the efficacy, safety and tolerability of taspoglutide compared to placebo in obese patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy.
- Trial name
- NCT00823992
- Testing
- taspoglutide
- Where
- 71 sites in United States, Canada and 8 more
- Volunteers
- 305 people
- Sponsor
- Hoffmann-La Roche
Obesity, Breast Cancer
BCRL Prevention Pilot
The purpose of this study is to establish feasiblity of recruiting obese breast cancer survivors at the end of treatment, getting those survivors to lose weight and attend follow-up visits for 6 months.
- Trial name
- NCT01166672
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Overweight, Obesity
PACIFIC: Providing Adults Collaborative Interventions For Ideal Changes
The objective of this proposed study is to collect initial efficacy data on ROC and ROC + BWL compared to an active comparator (AC) and to BWL.
- Trial name
- ROC (NCT02516839)
- Testing
- Regulation of Cues (ROC), Behavioral Weight Loss (BWL), BWL + ROC
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- University of California, San Diego
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