Clinical trials: Treatment Of Obesity
Pediatric Obesity, Adolescent Obesity
The Role of High Intensity Interval Training in the Treatment of Adolescent Obesity
The study will compare the effects of High Intensity Interval Training (HIIT) with Moderate Intensity Continuous Training (CMIT) as part of a lifestyle intervention program on BMI change in adolescents age 12-16 with obesity.
- Conditions
- Pediatric Obesity, Adolescent Obesity, Weight Loss
- Trial name
- NCT03361644
- Testing
- High-Intensity Interval Training, Moderate-Intensity Continuous Training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Idiopathic Intracranial Hypertension
Idiopathic Intracranial Hypertension Treatment Trial
Idiopathic intracranial hypertension (IIH), also called pseudotumor cerebri, is a disorder of elevated intracranial pressure of unknown cause [Corbett, et al., 1982; Wall, et al., 1991].
- Trial name
- IIHTT (NCT01003639)
- Testing
- Acetazolamide, Formal weight loss counselling program
- Where
- 41 sites in United States, Canada
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Metabolic Syndrome
Therapeutic Effect of Green Seaweed Against Metabloc Syndrome
Metabolic syndrome is a major concern worldwide and in Pakistan as well. Metabolic syndrome is a pathologic condition which includes abdominal obesity, insulin resistance, hypertension and hyperlipidemia.
- Trial name
- NCT05786534
- Testing
- Green Seaweed
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Obesity, Extreme Obesity
Weight Loss Surgery in Adolescents With Extreme Obesity
The use of bariatric surgery in adolescents is controversial. On one side, bariatric surgery is the only effective treatment to achieve sustained weight loss in adults with extreme obesity.
- Trial name
- YES (NCT02062164)
- Testing
- bariatric surgery, conservative care
- Where
- 5 sites in Germany
- Volunteers
- 66 people
- Sponsor
- Prof. Dr. Martin Wabitsch
Obesity
A Study to Investigate the Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Characteristics and Food Effect of HSG4112 in High Doses
1. Study Objective i) To evaluate the safety, tolerability and pharmacokinetic/pharmacodynamic characteristics of HSG4112 after single and multiple oral administration of high doses in healthy subjects.
- Trial name
- NCT05310032
- Testing
- HSG4112
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Glaceum
Diabetes Mellitus, Type 2
Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes
The main objective of this trial is to evaluate whether maridebart cafraglutide is non-inferior to semaglutide in improving glycemic control in participants with type 2 diabetes (T2D) who are receiving metformin treatment, with…
- Trial name
- MARITIME-T2D-3 (NCT07866066)
- Testing
- Maridebart cafraglutide, Semaglutide
- Volunteers
- 1,300 people
- Sponsor
- Amgen
Post-operative Complications, Surgical Site Infection
The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
The purpose of this study is to compare the post-surgical standard-of-care dressing to the Prevena™ Incision Management System in women undergoing Cesarean section surgery.
- Conditions
- Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
- Trial name
- NCT01450631
- Testing
- Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- KCI USA, Inc
Obesity, Skeletal Muscle
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
The use of glucagon-like peptide receptor agonists (GLP-1 RAs) may have clinically important effects on skeletal muscle mass (SMM), and physical function.
- Conditions
- Obesity, Skeletal Muscle, Brain Connectivity
- Trial name
- NCT07091500
- Testing
- Exercise training, Semaglutide, Therapy Cessation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes
Laparoscopic Bariatric Surgery to Treat Type 2 Diabetes in Obese Patients
A large number of research studies on people who were morbidly obese (extremely overweight), and had bariatric surgery (anti-obesity surgery) have shown that patients who were diabetic before surgery often experienced significant…
- Trial name
- NCT00428571
- Testing
- laparoscopic gastric bypass surgery, laparoscopic adjustable gastric banding, Intensive Medical Management
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hamilton Health Sciences Corporation
Obesity
Outcome of Combined Botulinum Toxin A Injection and Gastric Balloon Implantation in Obesity Treatment
Obesity, which is defined as the accumulation of fat in the body to a degree that impairs health, is defined as a serious public health problem and it is estimated that 13% (approximately 650 million) of the entire world…
- Trial name
- NCT05872932
- Testing
- gastric balloon implantation, botulinum toxin A injection
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Sebahattin Celik MD
Obesity
Inspiratory Muscle Training After Gastroplasty
The purpose of this study is to assess the effect of post-operative inspiratory muscle training on muscle strength and endurance in patients with obesity submitted to gastroplasty.
- Trial name
- NCT01084447
- Testing
- inspiratory muscle training, control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Obesity
Characteristics and Treatment Experiences of Individuals Using Injectable Semaglutide for Weight Management, a Cross-sectional Time-series Analysis, Multi-country Study.
The purpose of this study is to collect information for scientific research and to better understand the experiences of participants managing their weight.
- Trial name
- OUTSTEP-1 (NCT07154238)
- Testing
- No treatment given
- Where
- Germany
- Volunteers
- 2,546 people
- Sponsor
- Novo Nordisk A/S
Obesity, Overweight
Activity of Bioactive Natural Compounds as Potential Agonists of GLP1R
The goal of this clinical trial is to learn if natural bioactive compound jubenine works to reduce appetite and to favour weight loss. It will also learn about the safety of natural bioactive compound jubenine.
- Trial name
- BIOBESICOM (NCT06513715)
- Testing
- Control, Jubanine
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Pediatric Obesity
Qualitative Evaluation of Pediatric Obesity Therapeutic Education Programs
Obesity concerns almost the entire planet and is considered in France as a major public health issue: 17% of children are overweight and 4% obese.
- Trial name
- QUALIPOP (NCT06488235)
- Volunteers
- 32 people
- Sponsor
- University Hospital, Angers
Obesity
The Leisure-time Activity and Nutrition Program
The purpose of this investigation is to conduct an 8-week pilot study to examine the effects of two different leisure-time activity prescriptions on dietary intake, leisure-time activities, and weight loss in 30 adults receiving…
- Trial name
- LEAN (NCT01142206)
- Testing
- Dietary, Physical Activity, TV Watching + Physical Activity
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Chronic Insomnia, Overweight/Obesity
Cognitive Behavioral Therapy for Insomnia as an Adjunct to Time-restricted Eating on Weight Loss in Adults With Overweight or Obesity and Chronic Insomnia
Obesity (being overweight due to excess body fat) is a common health condition that increases the risk of developing problems such as diabetes, high blood pressure, and heart disease.
- Trial name
- NCT07770516
- Testing
- Flexible Time-restricted eating group (FTRE), Flexible Time-restricted eating plus cognitive behavioural therapy for insomnia group (CBTI+FTRE)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Obesity, Obesity, Morbid
Endoscopic Treatment of Overweight and Mild Obesity with ORBERA365
INTRODUCTION: Obesity is a critical health condition associated with high rates of morbidity and mortality. Conservative therapies such as dietary restriction, physical exercise, and pharmacological treatments have not prevented…
- Trial name
- ORBERA365 (NCT06785233)
- Testing
- Non-Adjustable Intragastric Balloon, ORBERA365
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaiser Clinic and Hospital
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm
Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
This trial studies the safety and how well negative pressure wound therapy works in healing the abdominal incision in obese patients undergoing free flap breast reconstruction surgery.
- Conditions
- Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
- Trial name
- NCT04003038
- Testing
- Negative Pressure Wound Therapy, Wound Care Management
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Morbid Obesity
Comparison of Mini Gastric Bypass and Roux-en-Y Gastric Bypass
This study compares Roux-en-Y gastric bypass with single anastomosis gastric bypass in a randomized prospective setting. This study also adresses the issue of bile reflux after MGB.
- Trial name
- RYSA (NCT02882685)
- Testing
- Roux-en-y gastric bypass, Single anastomosis gastric bypass
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Helsinki University Central Hospital
Obese, Obesity, Morbid
Treatment of Periodontitis in Obese Individuals
Obesity and gum diseases are highly prevalent in all parts of the world. Obesity can negatively influence severity and progression rates of gum diseases.
- Conditions
- Obese, Obesity, Morbid, Periodontitis
- Trial name
- CLIMBEO (NCT03103204)
- Testing
- One-stage full-mouth disinfection with chlorhexidine
- Where
- Brazil
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Taubate
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