Clinical trials: Treatment Of Obesity
PreDiabetes, NAFLD
Effects of Almonds in Glucose-intolerant Adults (AGAMEMNON)
Tree nuts - such as almonds - contribute to beneficial effects of the Mediterranean diet on risk for cardiovascular events, type 2 diabetes, dyslipidemia, hypertension, inflammation and non-alcoholic fatty liver disease.
- Trial name
- AGAMEMNON (NCT06413069)
- Testing
- Raw whole almonds
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Charite University, Berlin, Germany
Overweight and Obesity
Text2bHealthy: Using Innovative Methods in Childhood Obesity Treatment
In Canada, the number of obese children and adolescents has increased tremendously. Interventions addressing diet and physical activity have been successful in the short-term.
- Trial name
- NCT01800331
- Testing
- Text2bHealthy
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Obesity, Periodontal Diseases
Gingival Crevicular Fluid Levels of Prolactin Hormone in Obese Patients With Stage ii and Iii Periodontitis Before and After Non-surgical Periodontal Therapy
Obesity and periodontitis are among the most common chronic disorders affecting the world population, while Prolactin (PRL) is a neuroendocrine hormone that within the physiological range stimulates bone formation while mild to…
- Trial name
- NCT07571850
- Testing
- Obese patients with stage II and III periodontitis and non surgical peridontal therapy, obese patients with healthy periodontium with no intervention
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Type1diabetes, Obesity
Tirzepatide Use in People With Obesity and Type 1 Diabetes
Tirzepatide, a gut hormone-based medication, has shown promising results in treating obesity, with ~22% weight loss and mild side effects.
- Trial name
- NCT07096908
- Testing
- Tirzepatide
- Where
- Kuwait
- Volunteers
- 60 people
- Sponsor
- Dasman Diabetes Institute
Childhood Obesity
Improving Cardiometabolic Health of Youth on Antipsychotic Medication
Pediatric antipsychotic treatment is associated with significant obesity-related side effects, including weight gain, increased blood sugar, abnormal cholesterol, and risk of new onset diabetes.
- Trial name
- NCT02877823
- Testing
- Treatment, Control
- Volunteers
- 302 people
- Sponsor
- University of Maryland, Baltimore
Osteoarthritis Knee
Effect of Biomechanical Correction in Medial Tibiofemoral Joint Osteoarthritis
Effect of Biomechanical Correction of Tibia on Medial Joint space loading, Varus deformity and functional tasks in patients with medial tibiofemoral joint osteoarthritis in which participants will be taken.
- Trial name
- NCT04324931
- Testing
- Biomechanical corrections, Conventional Physiotherapy
- Where
- India
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Overweight, Obesity
Internet Assisted Obesity Treatment
High quality behavioral weight loss programs are not widely accessible. The Internet offers one way to deliver health behavior programs to a wider audience.
- Trial name
- iReach (NCT00265954)
- Testing
- internet, in-person and internet+in-person
- Where
- 2 sites in United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Obesity, Overweight, or Chronic Weight Management
Aleniglipron Phase 2 Body Composition Study
This is a randomized, double-blind, placebo-controlled study evaluating the effects of aleniglipron on body composition in participants living with obesity.
- Trial name
- NCT07169942
- Where
- 11 sites in United States
- Volunteers
- 71 people
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Obesity
IG vs ID Bitter Administration
We want to investigate whether bitter compounds, denatonium benzoate and quinine hydrochloride, have a distinct effect on gastrointestinal hormone release after infusion into the stomach or duodenum.
- Trial name
- IG vs ID (NCT03985865)
- Testing
- Intragastric quinine hydrochloride, Intragastric denatonium benzoate, Intraduodenal quinine hydrochloride
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Metabolic Disease
Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity
The purpose of this study is to conduct a three-arm 52-week, randomized controlled trial with double blind treatment to evaluate the effects of a drug called tirzepatide in combination with an innovative, culturally-appropriate…
- Trial name
- TRZ (NCT06009653)
- Testing
- Standard Care, Culturally-tailored dietary and behavioral intensive lifestyle intervention, Tirzepatide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
MOTIVOB-(Acceptance and Commitment Therapy Group Intervention for Obesity)Section
The purpose of the present study is to compare an Acceptance and Commitment Therapy (ACT) group intervention and a Cognitive Behavioral Therapy (CBT) group in a sample of obese individuals with respect to mid-term outcome.
- Trial name
- MOTIVOB-ACT (NCT03066531)
- Testing
- ACT-based intervention, CBT-based intervention
- Volunteers
- 156 people
- Sponsor
- Istituto Auxologico Italiano
CIDP, Immunoglobulin Deficiency
IVIG vs SCIG in CIDP
Current dosing practices for immunoglobulin G (IgG) may be inadequate in extreme body weight. The current study will evaluate the influence of body composition on intravenous and subcutaneous administration of immunoglobulin G in…
- Conditions
- CIDP, Immunoglobulin Deficiency, Chronic Inflammatory Demyelinating Polyneuropathy
- Trial name
- NCT05584631
- Testing
- Intravenous immune globulin G, Subcutaneous immune globulin G
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Morbid Obesity
Preventive Therapy With Ursodiol to Reduce the Incidence of Gallstones Formation in Patients After Bariatric Surgery
Risk factor of cholelithiasis is rapid weight loss after bariatric surgery and change in the gallbladder function which is secondary to surgery.
- Trial name
- NCT02319629
- Testing
- URSODIOL
- Where
- Israel
- Volunteers
- 266 people
- Sponsor
- HaEmek Medical Center, Israel
Adolescent Obesity, Lifestyle Intervention
Lifestyle Intervention of Obese Teenagers (LITE) Program
Background: Family-based lifestyle intervention programmes have been known to reduce overweight and improve cardiovascular risk in adolescent obesity [1].
- Trial name
- NCT03458637
- Testing
- LITE Program and Usual Care, Usual Care
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Obesity, Diabetes Mellitus, Type 2
A Study of the Safety and Efficacy of Topiramate in the Treatment of Obese, Type 2 Diabetes Patients on a Controlled Diet
The purpose of this study is to determine the efficacy and safety of topiramate compared with placebo in obese, Type 2 diabetic patients on a controlled diet.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset
- Trial name
- NCT00231530
- Testing
- topiramate
- Volunteers
- 541 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Loss-of-Control Eating, Obesity/Overweight
Pharmacological and Behavioral Treatments After Bariatric Surgery: Maintenance Treatment (Stage 2a)
This study will test the effectiveness of naltrexone/bupropion medication as a maintenance therapy for the treatment of loss-of-control eating and weight loss following bariatric surgery.
- Trial name
- NCT04605081
- Testing
- Naltrexone and Bupropion (NB) medication
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Treatment of Obesity
A Post-Market Surveillance Study of Using the g-Cath EZ for Treating Obesity
This is a multi-center, prospective study evaluating a treatment for obesity.
- Trial name
- NCT03721731
- Testing
- Obesity treatment with a Plication device
- Where
- 2 sites in Spain
- Volunteers
- 39 people
- Sponsor
- USGI Medical
Sports Physical Therapy
WB-EMS Increase Energy Expenditure at Rest and During Uphill Walking Exercise
Whole-body electrical stimulation (WB-EMS) has become increasingly popular as a tool to provide additional benefits compared to conventional exercise.
- Trial name
- NCT05218512
- Testing
- WB-EMS
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Overweight and Obesity
Weight Loss Goals and Satisfaction Survey
The goal of this observational survey pilot study is to learn how 3D visualization tools (i.e., personalized avatars) influence weight loss goals, satisfaction, confidence, and commitment compared to numerical weight outcomes in…
- Trial name
- NCT07541872
- Testing
- Personalized 3D Body Visualization
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
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