Clinical trials: Treatment Of Obesity
Obesity, Inflammation
Dapiglutide for the Treatment of Obesity
This study is an investigator-initiated, proof-of-concept, randomised, double-blind, placebo-controlled, parallel-group, single-centre clinical trial investigating the body weight loss potential of dapiglutide, a dual…
- Trial name
- DREAM (NCT05788601)
- Testing
- Dapiglutide
- Where
- Denmark
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Obesity, Overweight
THE ENLIGHTEN STUDY
The primary objective of this study is to demonstrate the safety and efficacy of the Elipse Gastric Balloon System for the treatment of obese adults.
- Trial name
- NCT03261453
- Testing
- Active Elipse Device
- Where
- 12 sites in United States
- Volunteers
- 400 people
- Sponsor
- Allurion Technologies
Disordered Eating Behaviors, Binge Eating
Enhanced Cue Exposure Therapy for Negative Emotional Eating
The current study aims to evaluate the efficacy of Enhanced Cue Exposure Therapy (E-CET) in reducing negative emotional eating (NEE), compared to an active control intervention, behavioral lifestyle intervention (BLI), in a…
- Trial name
- NCT06012045
- Testing
- Enhanced Cue Exposure Therapy, Behavioral Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Acupuncture
Efficacy of Abdominal Catgut Embedding Combined With Auricular Acupressure Therapy for Obese Patients
Objective: obesity is an important risk factor of chronic diseases, which not only threatens people's health, but also an important topic of public health.
- Trial name
- NCT06133205
- Testing
- Catgut Embedding at acupoints
- Where
- Taiwan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Overweight and Obesity
Passive Sensing Technology for Lapse Measurement
Behavioral obesity treatment (BOT) produces clinically significant weight loss and health benefits for many individuals with overweight/obesity and cardiovascular disease (CVD).
- Trial name
- NCT03739151
- Testing
- Behavioral Obesity Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The Miriam Hospital
Obesity
Combination of Topiramate and Empagliflozin is Considered a Good Option for the Treatment of Obesity
The aim was to show if a combination of topiramate and empagliflozin have the greatest weight decreasing effect in comparison to each drug alone and to group with no treatment( control group). .
- Trial name
- NCT04043702
- Testing
- The intervention being studied
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ministry of Health and Population, Egypt
Obesity
Moxibustion Combined With Characteristic Lifestyle Intervention of Traditional Chinese Medicine in the Treatment of Abdominal Obesity: A Study Protocol for a Randomized Controlled Trial
This study will investigate whether the combination of moxibustion and characteristic lifestyle intervention of TCM can alleviate the clinical symptoms and improve quality of life and mental health in patients with abdominal…
- Trial name
- NCT04501198
- Testing
- moxibustion combined with characteristic lifestyle intervention of traditional chinese medicine, Moxibustion combined with lifestyle intervention., lifestyle intervention
- Volunteers
- 150 people
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Polycystic Ovary Syndrome, Overweight
Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
The purpose of this study is to determine the effects of stress reduction on glucose, blood pressure, quality of life and overall health and well-being in overweight or obese women, either with Polycystic Ovary Syndrome (PCOS) or…
- Conditions
- Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological
- Trial name
- NCT01464398
- Testing
- Stress reduction, Stress reduction with Health education
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Milton S. Hershey Medical Center
Menopause, Type 2 Diabetes
Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis
The overall aim is to investigate the hypothesis that restoring E2 levels through MHT improves glucose and energy homeostasis and potentiates the beneficial effects of GLP-1RA in early postmenopausal women with pre- or existing…
- Trial name
- DECLARED-CT (NCT06715514)
- Testing
- GLP-1 Receptor Agonist, Menopausal Hormone Therapy
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Lia Bally
Diabetes
Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 Diabetes
Type 1 Diabetes (T1DM) is a disease characterised by immune mediated destruction of the insulin-producing pancreatic beta cells. Overtime, obvious insulin deficiency develops which requires insulin therapy.
- Trial name
- NCT06762314
- Testing
- Insulin, Semaglutide, Empagliflozin
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Mostafa Bahaa
Diabetes Mellitus Type 2 in Obese
"The Effect of Reiki on Metabolic Parameters in Obese Type 2 Diabetes Patients''
The increase in the prevalence of diabetes and the loss of various organs and functions in the individual as a result of complications caused by diabetes affect the life expectancy and quality of individuals, and cause social and…
- Trial name
- NCT05942079
- Testing
- REİKİ
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Hasan Kalyoncu University
Non-alcoholic Steatohepatitis (NASH)
Endoscopic Bariatric Therapy in NASH Cirrhosis
Non-alcoholic steatohepatitis (NASH) is a growing public health problem that affects more than 5% of the population and can lead to cirrhosis and hepatocellular carcinoma.
- Trial name
- ETHIC (NCT04281303)
- Testing
- Endoscopic vertical gastroplasty
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Hypothalamic-pituitary Lesions, Craniopharyngiomas
Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions
In children treated for intracranial lesions, the 2 factors of the obesity are : the location of the lesion (hypothalamic-pituitary region) and craniopharyngiomas
- Trial name
- NCT00306683
- Testing
- DIAZOXIDE
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Obesity
Exploring the Familial Reach of Adolescent Obesity Treatment
An observational study ancillary to the randomized clinical trial (RCT) TEENS+ (R01HD095910), a family-based lifestyle intervention, for adolescents with obesity, to determine: 1) if family-wide changes to the shared home…
- Trial name
- NCT05780970
- Testing
- No intervention
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Virginia Commonwealth University
Type 2 Diabetes, Obesity
Japanese Single and Multiple Ascending Dose, Safety, Tolerability, Pharmacokinetic (PK) & Pharmacodynamic (PD) Study of AZD7687
This is a study in Japanese healthy volunteers to determine the safety and tolerability of the compound AZD7687. It will also assess how the body handles the drug and how it responds to the drug following single dose followed by…
- Trial name
- JSMAD (NCT01217905)
- Testing
- AZD7687
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Obesity, Depression
Epidemiology and Care of Comorbid Obesity and Depression
We propose to: Conduct cross-sectional assessments of depression, disability, health-related quality of life, eating patterns, and eating attitudes in a population-based sample approximately 6000 women aged 40-60 with…
- Trial name
- NCT00169273
- Testing
- Structured behavioral weight loss group, Weight loss and cognitive-behavioral depression group
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Kaiser Permanente
Obesity
A Randomized Controlled Double Blinding Study of Intradermal Acupuncture Treatment on Obesity
The purpose of this study is to determine whether intradermal acupuncture is effective and safe in the treatment of obesity.
- Trial name
- NCT00414505
- Testing
- Intradermal Acupuncture Treatment
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Wonkwang University
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Obesity, Diabetes Mellitus, Type 2
A Study of the Efficacy and Safety of Topiramate in the Treatment fo Obese, Type 2 Diabetic Patients Treated With Metformin
The purpose of this study is to compare the efficacy (in terms of weight and hemoglobin type A1c [HbA1c]) and safety of topiramate (96 milligrams[mg] or 192 mg daily) with placebo in the treatment of obesity in Type 2 diabetic…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset
- Trial name
- NCT00231660
- Testing
- topiramate
- Volunteers
- 211 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
PCOS
Effect of Dietary Modifacation on Microbiota in Overweight and Obese Polycystic Ovary Syndrome Patients
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. The pathogenesis of PCOS is not fully understood.
- Trial name
- NCT03325023
- Testing
- Dietary and life style modification and probiotic Sanprobi Super Formula
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
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