Clinical trials: Treatment as Usual
Severe Mental Disorder, Psychological Trauma
EMDR in Psychiatric Inpatients With Severe Mental Disorder
The study of psychological trauma has become increasingly important in the field of mental health research due to the strong negative impact it has on the course and prognosis of psychiatric pathologies.
- Trial name
- NCT03664713
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Parc de Salut Mar
Low Back Pain, Chronic Pain
Chronic Low Back Pain Rehabilitation in Primary Care: an RCT
The aim of this study is to evaluate the effectiveness and cost-effectiveness of a new primary care intervention "Back on Track" as compared to usual primary care in patients with non-specific chronic low back pain in which…
- Conditions
- Low Back Pain, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT02220543
- Testing
- Back on Track intervention, Primary care as usual
- Where
- 8 sites in Netherlands
- Volunteers
- 25 people
- Sponsor
- Maastricht University Medical Center
Suicidal Ideation
(Cost)-Effectiveness of ABFT for Suicidal Youth.
Young adults who attempt to kill themselves is a common and serious mental health problem worldwide and certainly in Belgium and the Netherlands. Fatal suicide is the leading cause of death among young adults.
- Trial name
- REPAIR (NCT05965622)
- Testing
- Attachment Based Family Therapy (ABFT) + Treatment As Usual (TAU), Treatment As Usual (TAU)
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 138 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Schizophrenia, Schizoaffective Disorder
Adapted Cognitive/Affective Remediation for Cannabis Misuse in Schizophrenia
This study will integrate and adapt a cognitive remediation (Cognitive Enhancement Therapy [CET]) and an affect regulation (Personal Therapy [PT]) intervention for 50 individuals with schizophrenia that misuse cannabis.
- Trial name
- NCT01292577
- Testing
- CET/PT, Treatment as Usual
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Obesity, Extreme Obesity
Low-level Intervention for Adolescents With Extreme Obesity
While adolescents with obesity and extreme obesity are at increased risk for health complications, especially adolescents with extreme obesity rarely seek medical care, and sustained weigh loss is hardly ever achieved.
- Trial name
- STEREO (NCT01703273)
- Testing
- manual based low key group intervention (innovation), standardized, manual based routine care
- Where
- 6 sites in Germany
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Schizophrenia, Major Depressive Disorder
DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole
This is a 12 month, pragmatic trial designed to assess the differences in a digital medicine system (DMS)- ABILIFY MYCITE (Aripiprazole tablets with sensor)- measuring adherence versus treatment as usual (TAU) for adult patients…
- Conditions
- Schizophrenia, Major Depressive Disorder, Bi-Polar Disorder, Schizo Affective Disorder
- Trial name
- DIMES (NCT03881449)
- Testing
- ABILIFY MYCITE
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Durham VA Medical Center
Atrial Flutter Typical
Cryoballoon Ablation as First Line Treatment of Atrial Flutter
Current guidelines recommend radiofrequency catheter ablation of the cavotricuspid isthmus as treatment for symptomatic/drug-refractory atrial flutter, in spite of the fact that recurrences of flutter and incidence of…
- Trial name
- CRAFT (NCT03401099)
- Testing
- Radiofrequency ablation of CTI, Cryoballoon PVI
- Where
- 10 sites in Switzerland, United Kingdom
- Volunteers
- 113 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Depression, Trauma
Online Therapy Youth, Equivalent to Treatment As Usual?
With growing waiting lists in specialized youth mental health care (sGGZ) and shortages of care staff, finding creative solutions to respond to this scarcity issue is important.
- Conditions
- Depression, Trauma, Compulsive Disorder, Anxiety
- Trial name
- NCT06617663
- Testing
- EMDR, ACT
- Where
- Netherlands
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GGZ Noord-Holland-Noord
Chronic Depression, Persistent Depressive Disorder
Intensive Psychotherapy for Chronic Depression
The study evaluates whether Intensive psychotherapy show superior effect on chronic depression over TAU
- Conditions
- Chronic Depression, Persistent Depressive Disorder, Recurrent Major Depression
- Trial name
- NCT05221567
- Testing
- Psychotherapy
- Volunteers
- 280 people
- Sponsor
- Modum Bad
Panic Attacks, Chest Pain
The Effects of Treatment With Sertraline for Noncardiac Chest Pain
The purpose of this study is to determine whether care as usual or intervention (consisting of sertraline versus placebo), are effective in the treatment of panic disorder and/or depression driven noncardiac chest pain.
- Conditions
- Panic Attacks, Chest Pain, Depression
- Trial name
- NCT01114100
- Testing
- sertraline
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Maastricht University Medical Center
Anorexia Nervosa
Self-Help And Recovery Guide in Eating Disorders
The aim of this study is to test a novel guided self-help intervention for patients with Anorexia Nervosa. The 6-week intervention includes the use of self-help materials (i.e.
- Trial name
- SHARED (NCT02336841)
- Testing
- Treatment as usual + Recovery MANTRA, Treatment as usual + feedback
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- King's College London
Social Anxiety Disorder
RESCCUE4 - Group CBT for Social Anxiety in Adolescents
This randomized controlled trial aims to evaluate the efficacy of a 2-month group Cognitive Behavioral Therapy (CBT) intervention compared to a structured psychoeducational treatment as usual (TAU) in adolescents diagnosed with…
- Trial name
- NCT07464561
- Testing
- Group Cognitive Behavioral Therapy, Psychoeducational Group Intervention
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Acquired Brain Injury
Does Improved Ability to Achieve Single Leg Stance Lead to a More Efficient Gait Pattern in Adults With Acquired Brain Injury?
The purpose of the study is to see if a person can stand better on their weaker leg does this improve their walking ability following treatment specifically aimed at standing on leg.
- Trial name
- NCT04062149
- Testing
- single leg stance treatment, Usual physiotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Anorexia Nervosa, Bulimia Nervosa
Eating Disorders: Online Self-help & Usual Treatment (TAU) vs TAU Only
A pilot study exploring whether individuals receiving usual treatment (CBT) from the specialist NHS Tayside Eating Disorders Service and accessing the online self-help "Smart Eating" programme have improved treatment outcomes…
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, Other Specified Feeding or Eating Disorder
- Trial name
- NCT03107221
- Testing
- "Smart Eating" internet-based self-help programme
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Depression
The Early Medication Change (EMC) Trial
The EMC trial investigates for the first time prospectively whether Major Depression Disorder patients with non-improvement after 14 days of antidepressive treatment with EMC are more likely to become remitters compared to…
- Trial name
- EMC (NCT00974155)
- Testing
- Escitalopram, venlafaxine, lithium, Escitalopram, venlafaxine
- Where
- Germany
- Volunteers
- 889 people
- Sponsor
- K. Lieb
Depression - Major Depressive Disorder, Depression Disorder
Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression
The primary aim of this study is to evaluate the efficacy and tolerability of a combined Virtual Reality (VR)-based mindfulness intervention and pharmacological treatment compared with pharmacological treatment alone in reducing…
- Conditions
- Depression - Major Depressive Disorder, Depression Disorder, Depression Chronic, Treatment-Resistant Major Depressive Disorder
- Trial name
- NCT07422519
- Testing
- Virtual-Reality-based mindfulness intervention, Esketamine Treatment as Usual (ESK)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Panic Disorder, Agoraphobia
Clinical Trial of a Group Self-management Support Program for Anxiety Disorders
Background. Self-management support is a complementary approach to treatment that aims to educate participants on the nature of anxiety and to improve their strategies to manage symptoms and well-being, thus presenting the…
- Conditions
- Panic Disorder, Agoraphobia, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05124639
- Testing
- Group self-management support program for anxiety disorders
- Where
- Canada
- Volunteers
- 414 people
- Sponsor
- Université de Sherbrooke
Computer + Fluency, Computer Only
Evaluation of a Computerized Opioid Overdose Prevention Program
Unintentional fatal drug overdose (OD) is now the 2nd leading cause of accidental death in the general population. Fatal OD from opioid analgesics specifically has increased over 400% between 1999 and 2008, and nonfatal overdose…
- Conditions
- Computer + Fluency, Computer Only, Treatment as Usual
- Trial name
- NCT02040077
- Testing
- Computer + Fluency, Computer Only, Treatment as Usual
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Johns Hopkins University
Depression
Post Marketing Study to Evaluate the Resource Utilization of Patients Suffering From Resistant Depression Treated With Deep TMS in Comparison to Treatment as Usual
The aim of the study is to evaluate the efficacy of the Deep TMS compare to TAU and the different in resource utilization of treating depression with Deep TMS compare to the TAU.
- Trial name
- NCT02260765
- Testing
- dTMS
- Where
- United States
- Sponsor
- Brainsway
Somatic Symptom and Related Disorders, Intensive Short Term Dynamic Psychotherapy
Halifax Somatic Symptoms Disorder Trial
The purpose of this pilot study is to compare the effectiveness of Intensive Short-Term Dynamic Psychotherapy (ISTDP) plus Medical Care As Usual (MCAU) compared to MCAU for Somatic Symptom and Related Disorders (SSRD).
- Trial name
- NCT02076867
- Testing
- Intensive Short-Term Dynamic Psychotherapy, Medical Care As Usual (MCAU)
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Nova Scotia Health Authority