Clinical trials: Trendelenburg Position
Lidocaine, Optic Nerve Sheath Diameter
Lidocaine Infusion on Optic Nerve Sheath Diameter in Laparoscopic Hysterectomy in Trendelenburg Position
We hypothesize that intravenous lidocaine infusion may have beneficial effect to patients undergoing laparoscopic surgeries in Trendelenburg position by preventing ICP elevation.
- Conditions
- Lidocaine, Optic Nerve Sheath Diameter, Laparoscopic Hysterectomy, Trendelenburg
- Trial name
- NCT05690087
- Testing
- Lidocaine, sodium chloride 0.9% solution
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Post-induction Hypotension
Comparison of the Hemodynamic Effect of Three Positions During Induction of Anesthesia
The most common methods for prevention of post-induction hypotension are preoperative fluid loading and vasopressors. Leg elevation induces an intrinsic transfusion of 150 mL blood from the lower limbs to the central fluid…
- Trial name
- NCT03996213
- Testing
- head down position, leg elevation position
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Cairo University
Laparoscopic Gynecological Surgery
Effects of Standard and Modified Z-Trendelenburg Positions on Cerebral Oxygenation and Optic Nerve Sheath Diameter
The purpose of this study is to compare the effects of the standard Trendelenburg position and the modified Z-Trendelenburg position on cerebral oxygenation and optic nerve sheath diameter (ONSD) in patients undergoing…
- Trial name
- MOD-TREND (NCT07632287)
- Testing
- Standard Trendelenburg Position, Modified Z-Trendelenburg Position
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Lung Function
Lung Function After Robot-assisted Radical Prostate Ectomy
The aim of our study is to investigate if the use of the AirSeal insufflation system impairs the lung function of patients less than a conventional system in patients undergoing robot-assisted laparoscopic radical prostatectomy…
- Trial name
- NCT02066246
- Testing
- AirSeal, Olympus UHI-3
- Where
- 2 sites in Germany
- Volunteers
- 192 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pneumoperitoneum, Trendelenburg Position
End-expiratory Pressure During Laparoscopic Surgery in the Trendelenburg Position by Electrical Impedance Tomography
Pneumoperitoneum (PNP) and the position of the patient required for laparoscopic surgery lead to pathophysiological changes that complicate anesthesia.
- Conditions
- Pneumoperitoneum, Trendelenburg Position, Laparoscopic Surgery
- Trial name
- CP-EIT (NCT06481124)
- Testing
- electrical impedance tomography
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Breech Presentation of Fetus With Successful Version
Trendelenburg Positioning and External Cephalic Version Outcome
Women at term (over 37 weeks) that are candidates for external cephalic version will be positioned in the trendelenburg position 5 minutes prior to external cephalic version performance and during the procedure.
- Trial name
- NCT04585256
- Testing
- Trendelenburg positioning
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Rambam Health Care Campus
Airway Management
Airway Changes in Patients Undergoing Elective Surgical Procedures in the Prone and Trendelenburg Positions
The goal of this study is to track the intraoperative changes that occur in the airways of patients undergoing 1) laparoscopic surgeries in the Trendelenburg position, and 2) spinal surgeries in the prone position, as well as the…
- Trial name
- NCT02738788
- Testing
- Intubation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Tufts Medical Center
Laparoscopic Surgery
The Impact of Anesthesia and Positioning on Cerebral Blood Flow and Pressure in Patients Undergoing Laparoscopic Surgery
The aim of this observational study was to understand the effect of ReverseTrendelenburg position, Trendelenburg position on intracranial pressure and carotid blood flow in patients undergoing laparoscopic surgery.
- Trial name
- NCT06669689
- Testing
- operating position, pneumoperitoneum
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaguang Duan
Uterine Myoma, Ovarian Cyst
The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
In patients undergoing gynecologic laparoscopic surgery with trendelenburg position, the disturbance of pulmonary gas exchange frequently occurs due to high intra-abdominal pressure.
- Conditions
- Uterine Myoma, Ovarian Cyst, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01379313
- Testing
- conventional I:E ratio, 1:1 ratio, 2:1 group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Ischemic Stroke
Head Down Position for Successful Recanalization of Anterior Circulation Large Vessel Occlusion (HOPES4)
This is a prospective, randomized, open label, blinded-end point, single-center study, aiming to investigate the effect of head down position in anterior circulation large vessel occlusion patients with successful recanalization…
- Trial name
- NCT06313710
- Testing
- head down position
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Shenyang Military Region
Prostate Cancer
Effect of Ramosetron on Heart Rate-corrected QT Interval During Robot-assisted Laparoscopic Prostatectomy With Steep Trendelenburg Position
Intraperitoneal insufflation of carbon dioxide may affect the sympathetic activity that leads to changes in ventricular re-polarization. This in turn can result in changes of heart rate-corrected QT (QTc) interval.
- Trial name
- NCT03232125
- Testing
- Ramosetron, Normal saline
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Prostate Cancer, Optic Nerve Sheath Diameter
Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted Prostatectomy
This prospective study aims to evaluate the effect of steep Trendelenburg position and pneumoperitoneum on optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic radical prostatectomy and open radical…
- Conditions
- Prostate Cancer, Optic Nerve Sheath Diameter, Robot-Assisted Radical Prostatectomy, Steep Trendelenburg Position With Penumoperitoneum in Robot Assisted Laparoscopic Prostatectomy
- Trial name
- ONSD-RALP (NCT07491198)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ege University
IOP
Effect of Acetazolamide on Intraocular Pressure After Being in the Trendelenburg Position.
Perioperative vision loss following laparoscopic colorectal surgery is rare but has been reported. Studies show Trendelenburg positioning during surgery can produce a significant rise in the IOP, and this rise is thought to be a…
- Trial name
- TaPPs (NCT03107429)
- Testing
- Acetazolamide, Trendelenburg Position
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Acute Kidney Injury, Subclinical Acute Kidney Injury
Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery
This prospective observational study aims to evaluate early subclinical acute kidney injury associated with pneumoperitoneum and Trendelenburg positioning during gynecological laparoscopic surgery.
- Trial name
- NCT07704242
- Testing
- Pneumoperitoneum and Trendelenburg Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Hemodynamic Instability, Cardiovascular Complication
Evaluation of Cardiac Functions in Deep Trendelenburg Position
Robotic-assisted laparoscopic prostatectomy (RALP) is a surgical method with good short-term results and accepted as the gold standard because of its minimal invasiveness.
- Trial name
- NCT05685979
- Testing
- Robotic-assisted laparoscopic prostatectomy in deep Trendelenburg position.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Acibadem University
Pressure Incidence Prevention, Pain
The Effect of Different Support Surface Applications
This study was designed as a randomized controlled experimental study to compare the effects of two support surfaces-gel pads (used in routine practice) and microbead-filled pads-placed under the shoulders in the steep…
- Trial name
- NCT06974552
- Testing
- microbead-filled support surfaces, Jel support surfaces
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Wounds and Injuries
Comparison of Two Different Procedures for Plexus Anesthesia
The purpose of this study is to investigate the influence of difference positioning on extension and efficacy of brachial plexus anesthesia at 20 minutes by using the axillary plexus block with supine positioning and a lateral…
- Trial name
- NCT00151112
- Testing
- Positioning and plexus anesthesia
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Prostate Cancer, Robotic Surgery
Effect of Dexmedetomidine on Heart-rate Corrected QT(QTc) Interval Prolongation During Robotic-assisted Laparoscopic Radical Prostatectomy -Randomized Blind Clinical Trial-
Sympathetic activity could be increased during robot-assisted laparoscopic radical prostatectomy, which is performed in a steep trendelenburg position under CO2 pneumoperitoneum.
- Trial name
- NCT02536014
- Testing
- Dexmedetomidine, Saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Colorectal Neoplasms
Effect Inverse Ratio Ventilation on Arterial Oxygenation and Respiratory Mechanics During lapaLAR
Changes of inspiration: expiration ration from 1:2 to 1:1 could improve the arterial oxygenation and respiratory mechanics
- Trial name
- NCT01897584
- Testing
- inverse IE
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Gachon University Gil Medical Center
Post Operative Pain, Shoulder Pain
The Effect of Postoperative Modified Trendelenburg Position to Decrease Shoulder Pain After Laparoscopic Hysterectomy: A Randomized Controlled Trial
Laparoscopic surgery is commonly used procedure in diagnostic and treatment including Hysterectomy. Post laparoscopic shoulder pain is common side effect mostly occur after surgery.
- Conditions
- Post Operative Pain, Shoulder Pain, Gynecologic Disease
- Trial name
- NCT05428982
- Testing
- Postoperative Modified Trendelenburg position
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand