Clinical trials: Tricuspid Regurgitation
Tricuspid Regurgitation
Measurement of Tricuspid Regurgitation Volume for Assessment of Tricuspid Regurgitation Using 3D Transesophageal Echocardiography
This study is a prospective observational chart review. The aim of the study is to evaluate tricuspid regurgitation volume using 3D volumetric assessment as an accurate method for tricuspid regurgitation severity in comparison to…
- Trial name
- NCT05130775
- Testing
- Transesophageal echocardiograpgy
- Where
- United States
- Sponsor
- Tufts Medical Center
Tricuspid Regurgitation, Mitral Regurgitation
Concomitant Tricuspid Repair in Patients With Left Heart Surgery
Tricuspid regurgitation is common in patients with severe left heart diseases, such as degenerative mitral regurgitation. However, the evidence base is insufficient to inform a decision about whether to perform concomitant…
- Conditions
- Tricuspid Regurgitation, Mitral Regurgitation, Cardiopulmonary Bypass
- Trial name
- NCT05595187
- Testing
- Tricuspid repair
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanjing Medical University
Tricuspid Regurgitation, Heart Failure
The Long-term Course of Moderate Tricuspid Regurgitation
To evaluate the long-term clinical outcome of a cohort of patients suffering from moderate tricuspid regurgitation (TR), regardless of its etiology.
- Conditions
- Tricuspid Regurgitation, Heart Failure, Echocardiography
- Trial name
- LOCOMOTRI (NCT06169345)
- Testing
- Echocardiographic evaluation
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS San Raffaele
Symptomatic Severe Tricuspid Regurgitation
Transcatheter Treatment of Tricuspid Valve Regurgitation
Tricuspid Regurgitation induces an asymmetric enlargement of the tricuspid valve (TV) annulus causing a reduction of leaflets coaptation. Annular dilation continues even after surgical treatment.
- Trial name
- NCT06093828
- Testing
- TriFlo Tricuspid Flow Optimizer
- Where
- 4 sites in Italy
- Volunteers
- 40 people
- Sponsor
- TriFlo Cardiovascular, Inc.
Tricuspid Valve Regurgitation
MATTERS Study - Mistral Percutaneous Tricuspid Valve Repair FIM Study
The Mistral is an investigational device intended for percutaneous trans-catheter repair in high risk for surgery individuals suffering from functional Tricuspid Regurgitation (TR).
- Trial name
- NCT04071652
- Testing
- Mistral implantation
- Where
- 3 sites in Israel
- Volunteers
- 17 people
- Sponsor
- Mitralix
Tricuspid Valve Regurgitation
MATTERS II - Mistral Percutaneous Tricuspid Valve Repair FIM Study
The Mistral is an investigational device intended for percutaneous trans-catheter repair in high risk for surgery individuals suffering from functional Tricuspid Regurgitation (TR).
- Trial name
- NCT04073979
- Testing
- Mistral implantation
- Where
- 4 sites in Germany
- Volunteers
- 9 people
- Sponsor
- Mitralix
Tricuspid Regurgitation Congenital
Multiparametric Approach to Identify a CMR-based Tricuspid Regurgitation Classification
The aims of this study are: 1. to explore a novel 2D-Cardiovascular magnetic resonance (CMR) indirect method for tricuspid regurgitation (TR) quantification (ATRIAL method) relying on right atrium variables, and assess its…
- Trial name
- TRAC (NCT05748041)
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- IRCCS Policlinico S. Donato
Tricuspid Regurgitation, Right Heart Failure
Pforzheim Tricuspid Valve Registry - Outcomes of Percutaneous Tricuspid Valve Repair
The Pforzheim Tricuspid Valve Registry study is designed to confirm the safety and performance of the TriClip™ device in a contemporary real-world setting in critically ill patients.
- Conditions
- Tricuspid Regurgitation, Right Heart Failure, Cardiac Remodeling, Ventricular, Cardiac Remodeling, Atrial
- Trial name
- NCT05179616
- Testing
- Transcatheter edge-to-edge tricuspid valve repair
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Helios Klinikum Pforzheim
Valvular Heart Disease, Tricuspid Valve Regurgitation
Short Term Outcomes Of Tricuspid Valve Annuloplasty Using A Flexible Band
Functional tricuspid regurgitation (FTR) remains a common finding in patients with left-sided valvular heart diseases especially mitral valve regurgitation or stenosis.
- Trial name
- NCT05936125
- Testing
- Annuloplasty Using Flexible Band
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Valvular Heart Disease, Mitral Valve Disease
Prevalence Study of Cardiovascular Diseases in a Population ≥ 65 Years in Italy
This registry is a large-scale epidemiological study (PREVASC) aimed at estimating the prevalence of symptomatic and asymptomatic valvular hear disease in men and women aged over 65 years randomly selected in Italy.
- Conditions
- Valvular Heart Disease, Mitral Valve Disease, Aortic Valve Stenosis, Aortic Valve Insufficiency
- Trial name
- PREVASC (NCT05892588)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Cardiac Surgery, Tricuspid Valve Regurgitation
Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation
The mitral valve is the inflow valve into the main pumping chamber of the heart. It can become leaky or narrow, and cause blood to back up into the blood vessels of the lungs.
- Trial name
- NCT01246947
- Testing
- Tricuspid valve repair, Mitral surgery alone
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Maryland, Baltimore
Functional Tricuspid Regurgitation
Effectiveness and Durability Long-term Results of Tricuspid Annuloplasty With 3D Shaped Rings.
Interest in tricuspid valve disease has grown exponentially over the past few years, in response to increased interest in the poor prognosis of patients with functional tricuspid regurgitation (TR).
- Trial name
- NCT05836415
- Testing
- Tricuspid valve annuloplasty with 3D ring
- Where
- Italy
- Volunteers
- 168 people
- Sponsor
- Michele De Bonis
Tricuspid Regurgitation
Very Long-term (>15 Years) Results of Tricuspid Valve Repair.
Interest in Tricuspid valve disease grew exponentially in the last years in response to an increased awareness of the poor outcome of patients with functional Tricuspid Regurgitation (TR).
- Trial name
- NCT05836493
- Testing
- Ring annuloplasty, Suture procedure
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- Michele De Bonis
Remodeling, Cardiac, Tricuspid Regurgitation
Cardiac Remodeling and Prognosis in Secondar Tricuspid Regurgitation
The aim of this study is to improve the definition of the two main types of secondary tricuspid regurgitation.
- Trial name
- TRAP (NCT03159923)
- Testing
- Moderate to severe tricuspid regurgitation (≥ 2/4) diagnosed with echocardiography in patients stabilized.
- Where
- 17 sites in France
- Volunteers
- 200 people
- Sponsor
- Rennes University Hospital
Tricuspid Valve Regurgitation
Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System
The study is a multi-center, prospective, early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function, provide guidance for future clinical study designs and…
- Trial name
- NCT02471807
- Testing
- Edwards FORMA Tricuspid Transcatheter Repair System
- Where
- 5 sites in United States
- Volunteers
- 34 people
- Sponsor
- Edwards Lifesciences
Tricuspid Regurgitation
Surgical Treatment of Tricuspid Valve Regurgitation in Patients With Cardiac Implantable Electronic Devices: Long Term Results
Old trials aimed to evaluate Implantable Cardioverter-Defibrillator (ICD) safety and efficacy demonstrated a meaningful decreased rates of sudden death but an increased rate of hospitalization for heart failure .
- Trial name
- NCT05774821
- Testing
- Tricuspid valve surgery
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Michele De Bonis
Tricuspid Valve Regurgitation
Mistral Percutaneous Tricuspid Valve Durable Repair Pivotal Study
The Mistral is an investigational device intended for percutaneous trans-catheter repair in high risk for surgery individuals suffering from functional Tricuspid Regurgitation (TR).
- Trial name
- TRIBUTE (NCT05767645)
- Testing
- Mistral Procedure
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Mitralix
Tricuspid Regurgitation
A Prospective, Multicenter, Randomized Controlled Trial to Evaluate the Efficacy and Safety of the Transcatheter Tricuspid Valvuloplasty System in Patients With Severe or Above Tricuspid Regurgitation
To evaluate the efficacy and safety of the transcatheter tricuspid valve ring system produced by Shanghai Huihe Medical Technology Co., Ltd.
- Trial name
- NCT05770648
- Testing
- Transcatheter Annuloplasty, The guidelines guide medication
- Volunteers
- 64 people
- Sponsor
- Shanghai Huihe Medical Technology Co., Ltd
Murmur, Heart, Aortic Valve Stenosis
Development of an Algorithm to Differentiate Heart Murmurs Using Electronic Stethoscopes
The Eko CORE and DUO stethoscopes are FDA-approved electronic devices that have the capacity to record heart sounds. The study seeks to expand murmur detection to include VHD classification through the development of novel ML…
- Conditions
- Murmur, Heart, Aortic Valve Stenosis, Tricuspid Regurgitation, Mitral Regurgitation
- Trial name
- NCT04400513
- Testing
- Use of Eko CORE and Eko DUO electronic stethoscopes
- Where
- United States
- Volunteers
- 1,145 people
- Sponsor
- Eko Devices, Inc.
Tricuspid Regurgitation
Long-term Outcomes of Isolated Tricuspid Valve Surgery According to Preoperative Clinical and Functional Staging
Tricuspid regurgitation (TR) was identified as an independent prognostic factor associated with excess mortality and morbidity, independent of left ventricular (LV) function and pulmonary hypertension.
- Trial name
- NCT05721417
- Testing
- Tricuspid valve surgery
- Where
- Italy
- Volunteers
- 172 people
- Sponsor
- Michele De Bonis