Clinical trials: Trismus, open to volunteers
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Oral Submucous Fibrosis
Effect of Laser Photobiomodulation in Improving Mouth Opening in Oral Submucous Fibrosis
This a patient and outcome assessor blinded, multiple arm, randomized placebo controlled clinical trial. The goal of the study is to study the adjunctive effect of 940nm laser photobiomodulation therapy (PBMT) in precancerous…
- Trial name
- OSMFPBMT (NCT06639009)
- Testing
- 940nm diode laser photobiomodulation, Conventional non -Invasive management in Oral Submucous fibrosis
- Where
- India
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Dr. Shalini Gupta
Oral Health Care
The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery
Introduction: The aim of this study was to determine the effects of a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase (Tripser Forte N30, Incir Pharma, Turkey) on postoperative healing and to determine…
- Trial name
- Trypsin (NCT07269171)
- Testing
- Pain Assessment, Number of Analgesics Needed, Edema Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Postoperative Pain, Postoperative Complications
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars.
- Conditions
- Postoperative Pain, Postoperative Complications, Trismus, Periodontal Health
- Trial name
- NCT07180498
- Testing
- Chlorhexidine Gluconate 0.12% Mouthwash, Tea Tree Oil mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Harran University
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Post Operative Pain, Acute
Saline At Different Temperatures After 3rd Molar Surgery
This double-blind, single-center, split-mouth, randomized prospective clinical trial was conducted among 48 systemically and periodontally healthy patients who had bilaterally asymptomatic mandibular third molars.
- Trial name
- NCT06741696
- Testing
- Surgical extraction, saline irrigations
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital