Clinical trials: Tumor Gastric
Gastric Cancer
Prognostic Values of Inflammation-based Indices in Gastric Cancer
This study aims to evaluate the prognostic values of preoperative inflammation-based indices in patients undergoing potentially curative resection of gastric cancer.
- Trial name
- NCT05075421
- Testing
- Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Gulhane Training and Research Hospital
Advanced or Metastatic Solid Tumors, Microsatellite Instability Low
A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors
This is an open-label, non-randomized, Phase 1b/2 study to determine the safety and tolerability of NC410 when combined with a standard dose of pembrolizumab.
- Conditions
- Advanced or Metastatic Solid Tumors, Microsatellite Instability Low, Microsatellite Instability High, Microsatellite Stable
- Trial name
- NCT05572684
- Testing
- NC410, pembrolizumab
- Where
- 17 sites in United States
- Volunteers
- 97 people
- Sponsor
- NextCure, Inc.
Gastric Cancer
Clinical Trials for the Prevention of Gallstone Formation After Gastrectomy in Patient With Gastric Cancer
This study evaluates the efficacy and safety of DWJ1319 in the prevention of gallstone formation after gastrectomy in patient with gastric cancer.
- Trial name
- NCT02490111
- Testing
- DWJ1319
- Where
- 12 sites in South Korea
- Volunteers
- 521 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Pancreatic Adenocarcinoma, Ampulla of Vater Carcinoma
Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
The goal of this open-label randomized, multicenter, comparative phase II trial is to evaluate the efficacy of the immunotherapy, dostarlimab, as first-line treatment for deficient mismatch repair (dMMR)/microsatellite…
- Conditions
- Pancreatic Adenocarcinoma, Ampulla of Vater Carcinoma, Adrenocortical Carcinoma, Neuroendocrine Carcinoma
- Trial name
- Pan-MSI-ACSE (NCT06333314)
- Testing
- Dostarlimab, Chemotherapy
- Where
- 22 sites in France
- Volunteers
- 120 people
- Sponsor
- UNICANCER
Esophagus Cancer, Gastric Cancer
Predictive Model to Early Diagnosis of Anastomotic Leak After Esophagectomy and Gastrectomy.
The PROFUGO study (PRedictive Model for the early diagnosis of anastomotic leak after esophagectomy and gastrectomy) is proposed as a prospective and multicenter study at spanish national level that aims to develop, with the help…
- Conditions
- Esophagus Cancer, Gastric Cancer, Leak, Anastomotic, Complication
- Trial name
- PROFUGO (NCT05390684)
- Testing
- audit of complications, prospective data collection
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- Hospital Universitario La Fe
Gastric Cancer
Comparison of Delta-Shaped and Billroth II After TLDG
To compare the safety and feasibility of Delta-shaped anastomosis and Billroth II anastomosis after totally laparoscopic distal gastrectomy for gastric cancer(TLDG).
- Trial name
- TLDG (NCT02372747)
- Testing
- Delta-shaped anastomosis, Billroth II anastomosis
- Volunteers
- 78 people
- Sponsor
- The First Hospital of Jilin University
Gastric Cancer
Genomic and Dietary Aspects in Gastric Cancer Risk
Gastric Cancer (GC) ranks fourth in the number of deaths worldwide and it is sixth in Italy with almost 9,000 deaths in 2020. Survival of GC is one of the lowest reported amongst major cancers, thus making prevention a central…
- Trial name
- GenoStoP (NCT05934058)
- Where
- Italy
- Volunteers
- 383,980 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Esophageal Cancer, Gastric Cancer
Irinotecan in Treating Patients With Esophageal or Stomach Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of irinotecan in treating patients who have esophageal or…
- Trial name
- NCT00003748
- Testing
- irinotecan hydrochloride
- Where
- 25 sites in United States
- Volunteers
- 40 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Male Breast Cancer, Recurrent Breast Cancer
Interleukin-12, Paclitaxel, and Trastuzumab in Treating Patients With Solid Tumors
Phase I trial to study the effectiveness of interleukin-12, paclitaxel, and trastuzumab in treating patients who have solid tumors.
- Conditions
- Male Breast Cancer, Recurrent Breast Cancer, Recurrent Endometrial Carcinoma, Recurrent Gastric Cancer
- Trial name
- NCT00028535
- Testing
- trastuzumab, paclitaxel, recombinant interleukin-12
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Cancer Institute (NCI)
Neoplasms
Phase 1 Dose Escalation Study for VIP236 in Patients With Advanced Cancer
Determine the safety, tolerability, and maximum tolerated dose (MTD) of IV administered VIP236 as monotherapy in patients with advanced solid tumor cancer
- Trial name
- NCT05712889
- Testing
- VIP236 (Q3W), VIP236 (Q2W)
- Where
- 6 sites in United States, Australia
- Volunteers
- 29 people
- Sponsor
- Vincerx Pharma, Inc.
Gastric Cancer
The Number of Mesogastria Containing Metastatic Lymph Nodes Predicts Gastric Cancer Prognosis
To investigate the impact of the number of mesogastria containing metastatic lymph nodes on the prognosis of gastric cancer.
- Trial name
- NCT06697821
- Testing
- D2＋CME
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Jichao Qin
Gastric Cancer (GC)
Prehabilitation Plus ERAS in Gastric Cancer Surgery
This study aims to evaluate the impact of pre-habilitation combined with Enhanced Recovery After Surgery (ERAS) versus ERAS perioperative management alone on clinical outcomes in patients with gastric cancer undergoing…
- Trial name
- NCT07328633
- Testing
- Pre-habilitation Program, Enhanced Recovery After Surgery (ERAS) Protocol
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastric Cancer Adenocarcinoma Metastatic, Lymph Node Metastasis
AI-Based Prediction of Lymph Node Metastasis in Gastric Cancer Using Preoperative Multimodal Data
This study aims to develop and validate an artificial intelligence (AI) system that can predict whether lymph node metastasis has occurred in patients with gastric cancer before surgery.
- Conditions
- Gastric Cancer Adenocarcinoma Metastatic, Lymph Node Metastasis, Artificial Intelligence (AI) in Diagnosis
- Trial name
- NCT06957678
- Testing
- Artificial Intelligence-Based Predictive Model for Lymph Node Metastasis
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Qun Zhao
Esophagogastric Adenocarcinoma
Phase 2 Study of Telomelysin (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma
This is a phase II study of OBP-301 with pembrolizumab in advanced gastric and gastroesophageal junction adenocarcinoma that has progressed on at least 2 lines of prior therapy for advanced disease.
- Trial name
- NCT03921021
- Testing
- Telomelysin
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- Weill Medical College of Cornell University
Stomach Cancer
Effect of Mosapride Citrate on Gastrointestinal Motility After Laparoscopic Gastrectomy
"Mosapride citrate is a 5-hydroxytryptamine 4 receptor agonist, and is widely used as an agent to increase intestinal motility. Mosapride citrate has been demonstrated in in vitro and in vivo studies to increase both gastric and…
- Trial name
- NCT04493125
- Testing
- Mosapride citrate
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Gangnam Severance Hospital
Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
This clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood.
- Conditions
- Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT06131840
- Testing
- PF-08046050, bevacizumab, 5-Fluorouracil (5-FU)
- Where
- 48 sites in United States, Canada and 8 more
- Volunteers
- 914 people
- Sponsor
- Seagen, a wholly owned subsidiary of Pfizer
Gastric Adenocarcinoma, Gastric Cancer
Effect of Peritoneal Lavage on Surgery-induced Positive Peritoneal Cytology in Gastric Cancer Patients
Surgical manipulation and handling of a tumor may cause dissemination of cancer cells through peritoneal cavity after curative gastrectomy.
- Trial name
- NCT02287168
- Testing
- pre-gastrectomy peritoneal washing cytology, post-gastrectomy peritoneal washing cytology, post-lavage peritoneal washing cytology
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Breast Cancer, Stomach Neoplasms
Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival & Frozen Tissue Sample
The goal of this study is to study NIS expression in benign and malignant breast and thyroid samples using archival formalin-fixed paraffin-embedded tissue sections.
- Conditions
- Breast Cancer, Stomach Neoplasms, Salivary Gland Neoplasms, Thyroid Cancer
- Trial name
- NCT00568438
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Stanford University
Esophageal Neoplasms
Home Jejunostomy Feeding Following Esophagectomy/Gastrectomy
After surgery for oesophageal (gullet) or gastric (stomach) cancer, patients are routinely fed by means of a small feeding tube into the intestine (jejunostomy, JEJ) while they are in hospital.
- Trial name
- NCT01870817
- Testing
- Home jejunostomy feeding
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- University Hospitals, Leicester
Gastric Carcinoma
A Study of Apatinib Versus Docetaxol Patients With Advanced Gastric Cancer
This multicenter, randomized study will evaluate the efficacy and safety of apatinib compared to docetaxel treatment in patients with advanced gastric cancer.
- Trial name
- NCT02409199
- Testing
- Docetaxel, apatinib
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Zhongshan Hospital