Clinical trials: Tumor Gastric
Gastric Cancer
Clinical Trial of Chemosensitivity Test
To evaluate the usefulness of chemosensitivity test in evaluating the appropriate adjuvant cancer chemotherapy after gastric surgery
- Trial name
- NCT00287755
- Testing
- S-1
- Where
- 36 sites in Japan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Japan Clinical Cancer Research Organization
Esophageal Neoplasms, Stomach Neoplasms
Identification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer
The aim of this study is to identify biomarkers predicting response or resistance factors of a targeted therapy with trastuzumab in advanced gastric cancer.
- Trial name
- VARIANZ (NCT02305043)
- Testing
- non-interventional
- Where
- Germany
- Volunteers
- 549 people
- Sponsor
- University of Leipzig
Gastrointestinal Neoplasms, Gastric Cancer
Endoscopic Submucosal Dissection Registry
The purpose of this study is to monitor the success rates and completion rates for endoscopic submucosal dissection (ESD) for gastrointestinal (GI) cancers.
- Trial name
- ESD Registry (NCT01415609)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Advanced Gastric Cancer
A Phase I Clinical Study for Evaluating the Safety of MASCT-I in Advanced Soild Tumor
This study evaluate the safety and tolerance of MASCT-I(multiple-antigen specific cell therapy) combined with PD1 antibody in patients with advanced gastric cancer who failed in first-line chemotherapy.
- Trial name
- NCT03393416
- Testing
- MASCT-I, PD1 antibody
- Where
- China
- Volunteers
- 28 people
- Sponsor
- HRYZ Biotech Co.
Stage III Gastric Cancer
Immunonutritional Supplement After Total Gastrectomy in Patients With Stage III Gastric Cancer
Gastric cancer patients with stage III will be randomized to immune nutrition support or control group at discharge after total gastrectomy.
- Trial name
- CRUCIAL (NCT05253716)
- Testing
- ONS
- Where
- China
- Volunteers
- 696 people
- Sponsor
- Jinling Hospital, China
Gastric Cancer
5-FU, Leucovorin, Oxaliplatin and Docetaxel (FLOT) Versus Epirubicin, Cisplatin and 5-FU (ECF) in Patients With Locally Advanced, Resectable Gastric Cancer
Patients with locally advanced resectable adenocarcinoma of the stomach or the esophagogastreal junction without previous therapy will be treated with one of two chemotherapy combinations before and after surgery.
- Trial name
- NCT01216644
- Testing
- 5-Fluorouracil, Leucovorin, Oxaliplatin
- Where
- Germany
- Volunteers
- 716 people
- Sponsor
- Krankenhaus Nordwest
Stomach Neoplasm
Capeox Regimen Combined With Sintilimab and Bevacizumab for Gastric Cancer
The median survival time of first-line chemotherapy for advanced gastric cancer is about one year, and the treatment is still facing the bottleneck. This is a one-arm, open and prospective phase II clinical study.
- Trial name
- NCT05640609
- Testing
- Capeox regimen combined with Sintilimab and Bevacizumab
- Where
- China
- Volunteers
- 57 people
- Sponsor
- West China Hospital
Gastric Cancer (GC), Colorectal Cancer
Safety and Efficacy of NK510 to Treat Gastric Cancer and Colorectal Cancer
This study will evaluate the safety and efficacy of NK510 in the treatment of relapsed and refractory advanced gastric cancer and colorectal cancer.NK510 will be administered by intravenous infusion for systemic therapy and…
- Trial name
- NCT07166263
- Testing
- NK510
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Base Therapeutics (Shanghai) Co., Ltd.
Gastric Cancer
Phase III Study of TAS-118 Plus Oxaliplatin Versus S-1 Plus Cisplatin in Patients With Advanced Gastric Cancer
The purpose of this trial is to evaluate the efficacy of TAS-118 plus Oxaliplatin compared with S-1 plus Cisplatin in overall survival in patients with advanced gastric cancer.
- Trial name
- SOLAR (NCT02322593)
- Testing
- TAS-118 plus Oxaliplatin, S-1 plus Cisplatin
- Where
- 6 sites in Japan, South Korea
- Volunteers
- 711 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Stomach Neoplasm
Vactosertib and Durvalumab in Gastric Cancer
This trial will test the efficacy and safety of durvalumab in combination with vactosertib in patients with metastatic gastric cancers who failed ≥ 2 lines of chemotherapy
- Trial name
- NCT04893252
- Testing
- durvalumab and vactosertib
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Hark Kyun Kim
Gastric Cancer
Perioperative Application of Omega-3 Polyunsaturated Fatty Acids in Gastric Cancer Patients
To evaluate immunomodulatory effects of perioperative application of omega-3 polyunsaturated fatty acids in gastric cancer surgery, the effects of postoperative recovery, the improvement of nutritional status, incidence rate of…
- Trial name
- PAOPUFAGC (NCT01910948)
- Testing
- omega-3 polyunsaturated fatty acids
- Volunteers
- 100 people
- Sponsor
- Jian Suo
Pancreatic Ductal Adenocarcinoma, Esophageal Cancer
A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors.
The purpose of this clinical study is to learn about the safety and effects of the study medicine (called PF-08098488) in people with advanced solid tumors (cancer that cannot be removed with surgery or has spread to other parts…
- Conditions
- Pancreatic Ductal Adenocarcinoma, Esophageal Cancer, Carcinoma, Non-Small-Cell Lung (NSCLC), Gastric Carcinoma
- Trial name
- NCT07903415
- Testing
- PF-08098488
- Where
- 4 sites in United States
- Volunteers
- 280 people
- Sponsor
- Pfizer
Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck
A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors
This trial will look at a drug called sigvotatug vedotin (SGN-B6A) to find out whether it is safe for Chinese participants who have solid tumors. It will study sigvotatug vedotin to find out what its side effects are.
- Conditions
- Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma
- Trial name
- NCT06549816
- Testing
- sigvotatug vedotin
- Where
- 3 sites in China
- Volunteers
- 6 people
- Sponsor
- Seagen, a wholly owned subsidiary of Pfizer
Peritoneal Carcinomatosis
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) With Oxaliplatin In Patients With Peritoneal Carcinomatosis
PIPAC is a procedure that involves the administration of intraperitoneal chemotherapy using an innovative concept that enhances the efficacy by taking advantage of the physical properties of gas and pressure.
- Trial name
- PIPAC (NCT03172416)
- Testing
- Oxaliplatin, Oxaliplatin & Nivolumab
- Where
- 3 sites in Belgium, Singapore
- Volunteers
- 21 people
- Sponsor
- National University Hospital, Singapore
Gastrostomy, Computed Tomography Angiography
Gastrointestinal Surgery Study Group 2001
Gastric cancer is one of the most common malignace worldwide, which caused a dramatically death rate, especially in east Asian, such as Japan , South Korea and China.
- Conditions
- Gastrostomy, Computed Tomography Angiography, Clinical Outcome
- Trial name
- GISSG2001 (NCT04636099)
- Testing
- CT angiography(CTA)
- Where
- China
- Volunteers
- 382 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Solid Tumors (Pancreatic Cancer, Esophageal Cancer, Gastric Cancer, Cholangiocarcinoma, Lung Cancer and Ovarian Cancer)
An Exploratory Clinical Study to Evaluate the Safety and Efficacy of NK Cells (Combined With Standard Therapy) in the Treatment of Solid Tumor Patients
An exploratory clinical study to evaluate the safety and efficacy of NK cells (combined with standard therapy) in the treatment of solid tumor patients
- Trial name
- CCT-ANK-11 (NCT06284226)
- Testing
- Allogeneic NK(CCT-ANK-11)
- Sponsor
- Beijing Kejing Biotechnology Co., Ltd.
Stomach Cancer, Undifferentiated Type
Comparison of Endoscopic Resection and Surgery for Early Gastric Cancer With Undifferentiated Histological Type
This multi-center, randomized controlled trial is designed to evaluate clinical effectiveness and cost-effectiveness of ESD for undifferentiated type of EGC meeting the expanded indication compared with surgery.
- Conditions
- Stomach Cancer, Undifferentiated Type, Expanded Indication of Endoscopic Resection
- Trial name
- ERASE-GC (NCT04890171)
- Testing
- Endoscopic submucosal dissection, Surgery
- Where
- South Korea
- Volunteers
- 708 people
- Sponsor
- National Cancer Center, Korea
Esophageal Cancer, Gastric Cancer (GC)
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.
This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of [¹⁸F]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed gastric…
- Conditions
- Esophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction
- Trial name
- FAPI-GO (NCT07217704)
- Testing
- [18F]FAPI-74 PET/CT
- Where
- 19 sites in United States
- Volunteers
- 200 people
- Sponsor
- SOFIE
Stomach Neoplasms
Cisplatin and S-1 With or Without Nimotuzumab in Untreated Advanced Gastric Adenocarcinoma
In this open-label, single-center, small sample size, randomised, parallel-group, controlled study, the investigators aim to assess efficacy and safety of addition of nimotuzumab to CS chemotherapy in patients with previously…
- Trial name
- NCT02370849
- Testing
- nimotuzumab, cisplatin, S-1
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Chinese Academy of Medical Sciences
Gastric Cancer
Efficacy and Safety of Minimally Invasive D2+PAND Gastrectomy for Gastric Cancer With PAN Metastasis After Conversion Immunochemotherapy
This is a prospective, open-label, single-center, Phase II clinical trial. Thirty patients with HER2-negative gastric adenocarcinoma or gastroesophageal junction (GEJ) cancer, presenting with PAN metastasis (No.
- Trial name
- NCT07056010
- Testing
- curative minimally invasive gastrectomy with D2+PAND lymphadenectomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
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