Clinical trials: Tumors, Breast
Metastatic Breast Cancer
Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients
to evaluate whether bone marker can provide the valuable predictor of skeletal complications and whether regular assessing of NTX(N-telopeptide of type I collagen) and osteocalcin can be useful in advanced breast cancer patients…
- Trial name
- NCT00912938
- Testing
- zoledronic acid
- Where
- South Korea
- Volunteers
- 237 people
- Sponsor
- Korean Breast Cancer Study Group
Breast Cancer
MRI in Assessing Tumor Size in Women With Ductal Carcinoma In Situ
RATIONALE: Diagnostic procedures, such as MRI, may help find ductal carcinoma in situ and find out how far the disease has spread.
- Trial name
- NCT00874458
- Testing
- magnetic resonance imaging, radiomammography, ultrasound imaging
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Antoine Lacassagne
Breast Cancer, Male
Study on the Progress of Breast Cancer Cases in Males and the Assessment of Relapse Risk
An observational, Other Designs (OD) post-marketing, multicenter study, which will obtain retrospective data from male patients diagnosed with invasive breast cancer between 2000 and 2019 in the medical oncology departments of…
- Trial name
- NCT03800355
- Where
- 54 sites in Spain
- Volunteers
- 777 people
- Sponsor
- Spanish Breast Cancer Research Group
Breast Cancer Female, Physical Inactivity
Body Image and Physical Activity of Women with Breast Cancer
The goal of this self-initiated questionnaire-based follow-up clinical trial is to map the body image and physical activity of Hungarian women treated for breast cancer. The main questions it aims to answer are: 1.
- Conditions
- Breast Cancer Female, Physical Inactivity, Quality of Life, Body Image
- Trial name
- NCT06730815
- Where
- 2 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- University of Pecs
Breast Cancer
Water and Land-based Aerobic Training in Breast Cancer Survivors
Background: Breast cancer is the type of cancer that mostly affects women in the world. Although physical and psychological side effects accompany cancer and the aggressiveness of the treatment, regular practice of physical…
- Trial name
- WaterMama (NCT05520515)
- Testing
- Aquatic Training Plus Health Education, Land Training Plus Health Education, Health Education
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Federal University of Pelotas
Stomatitis, Oral Mucositis
Efficacy of SNX-1012 in the Treatment of Oral Mucositis
Oral mucositis (OM) is a common and debilitating toxicity induced by many chemotherapy (CT) regimens and by radiation to the head and neck.
- Trial name
- NCT00385515
- Testing
- SNX-1012 (meclocycline sulfosalicylate)
- Where
- 27 sites in United States, India
- Volunteers
- 81 people
- Sponsor
- Mucosal Therapeutics
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Blood Samples
Establishment of a tumor bank, consisting of blood samples of tumor patients and healthy people as controls. The blood samples will be collected systematically together with the corresponding clinical data.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01763125
- Testing
- Blood collection
- Where
- 6 sites in Austria, Belgium and 2 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Metastatic Breast Cancer
Eribulin in Brain Metastases From HER2-negative Breast Cancer
To evaluate the efficacy of eribulin for treatment of HER2-negative breast cancer brain metastases (BCBM)
- Trial name
- ERIBRAIN (NCT03637868)
- Testing
- Eribulin
- Where
- 7 sites in France
- Sponsor
- Institut Paoli-Calmettes
Breast Neoplasms
Implementation of a "Remission" Consultation in the Management of Patients Treated for Localized Breast Cancer
The main objective of this study is to describe the evolution in quality of life (QLQ-C30) for patients receiving breast cancer care at 3, 6 and 12 months after a "remission" consultation.
- Trial name
- REVIS (NCT02740491)
- Testing
- Remission Consultation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Breast Cancer, Ovarian Cancer
AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer
Background: Carboplatin is approved by the Food and Drug Administration to treat cancer. AZD2281 is an experimental drug in a class of agents called PARP inhibitors.
- Trial name
- NCT01445418
- Testing
- AZ2281 + Carboplatin
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer, Neoplasm, Breast
TCM Therapy Program Impact on Breast Cancer Patients' Vital Energy
The goal of this study is to evaluate the impact of the "Traditional Chinese Medicine Therapy Program for Reinforcing Vital Energy" on patients with breast cancer who are currently undergoing conventional Western medical…
- Conditions
- Breast Cancer, Neoplasm, Breast, Patient Participation, Mental Health Issue
- Trial name
- NCT06337214
- Testing
- Traditional Chinese Medicine Therapy Program for Reinforcing Vital Energy
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei City Hospital
Breast Cancer
A Study on the Efficacy and Safety of IPyC for HER2+ MBC
Between July 2020 and August 2024, 301 HER2-positive MBC patients from five tertiary centers received the regimen until disease progression or unacceptable toxicity.
- Trial name
- NCT06990347
- Testing
- Inetetamab and Pyrotinib Combined with Chemotherapy
- Where
- China
- Volunteers
- 301 people
- Sponsor
- Fujian Medical University
Neoplasm Malignant, Breast Cancer
Shorter Scalp Cooling Time in Paclitaxel
Chemotherapy-induced alopecia (CIA) is one of the most distressing side effects for patients. Scalp cooling can prevent or minimise CIA in approximately half of all patients, depending on many factors, e.g.
- Conditions
- Neoplasm Malignant, Breast Cancer, Ovarian Cancer
- Trial name
- COP (NCT03266185)
- Testing
- Shorter PICT
- Where
- Netherlands
- Volunteers
- 91 people
- Sponsor
- Leiden University Medical Center
Breast Cancer
Sac-TMT Plus KL-A167 in PD-L1+, HR+/HER2- Metastatic Breast Cancer After CDK4/6 Inhibitors
This is a Phase II single-arm study designed to evaluate the efficacy and safety of Sac-TMT + KL-A167 in 35 patients with PD-L1+, HR+/HER2- metastatic breast cancer who previously treated with CDK4/6 inhibitor.
- Trial name
- NCT07258108
- Testing
- Lucanisatuzumab plus tagolimumab
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Sun Yat-sen University
Metastatic Breast Cancer
Pilot Study of Bone Biopsy and Aspirate in Women With Metastatic Breast Cancer
This is a feasibility study to demonstrate the team's ability to collect bone marrow aspirates and biopsies for research purposes from women with metastatic breast cancer.
- Trial name
- NCT01975597
- Testing
- Bone marrow aspirates and biopsy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Michigan Rogel Cancer Center
Breast Cancer
Reducing Underuse of Early-Stage Breast Cancer Treatment in Minority Communities
The purpose of this study is to determine if a physician-centered intervention will help women with early stage breast cancer receive appropriate treatment.
- Trial name
- NCT00145197
- Testing
- Improving the Delivery of Effective Care to Minorities
- Where
- United States
- Volunteers
- 1,164 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Triple Negative Breast Cancer
Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy
This study will evaluate the efficacy and safety of antharcycline-based adjuvant chemotherapy compared with observation in triple negative breast cancer (TNBC) patients with residual invasive disease after platinum and taxanes…
- Trial name
- NCT04437160
- Testing
- Epirubicin or Pirarubicin, Cyclophosphamide
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Chinese Academy of Medical Sciences
HR-positive, HER2-negative and PIK3CA Mutation Advanced Breast Cancer
A Study of TQ-B3525 Tablets Combined With Fulvestrant Injection in Subjects With HR-positive, HER2-negative and PIK3CA Mutation Advanced Breast Cancer
This is a open-label, multicenter phase Ib study to evaluate safety and efficacy of TQ-B3525 tablets combined with fulvestrant injection in subjects with HR-positive, HER2-negative and PIK3CA mutation advanced breast cancer.
- Trial name
- NCT04355520
- Testing
- TQ-B3525, Fulvestrant injection
- Where
- 4 sites in China
- Volunteers
- 42 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
HER2 Negative Breast Cancer
Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy
This is a Phase II, two-arm, single center, patient preference study designed to evaluate the impact of omitting adjuvant chemotherapy in moderate to high-anatomical risk, low-genomic risk (men or premenopausal women T2-3N0 and…
- Trial name
- SELECT (NCT06953882)
- Testing
- Ribociclib 400mg, Letrozole 2.5mg, Anastrazole 1mg
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Breast Cancer Female, Anxiety
The Effect of Virtual Reality on Anxiety and Fatigue in Women With Breast Cancer Receiving Adjuvant Chemotherapy
It was aimed to determine the effect of virtual reality glasses application on anxiety and fatigue in women with breast cancer receiving adjuvant chemotherapy.
- Conditions
- Breast Cancer Female, Anxiety, Fatigue
- Trial name
- NCT05168696
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
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