Clinical trials: Tympanic Membrane Perforation
Tympanum; Perforation
General Anesthesia With or Without Local Ear Block in Middle Ear Surgeries
Background: Proper selection of anesthetic technique is important in middle ear microsurgery. Controlled hypotension in ear surgery decreases blood loss with improved quality of the surgical field, however, it is associated with…
- Trial name
- NCT03569046
- Testing
- local anaesthetic injection, Normal Saline Flush, 0.9% Injectable Solution, general anesthetic
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Abd-Elazeem Abd-Elhameed Elbakry
Tympanic Membrane Perforation
Comparison Tympanoplasty With Membrane Amniotic and Autologous Fascia
The tympanic membrane separates the middle and the outer ear from each other and consists of three layers. The outer layer is covered with squamous epithelium, a thick basement membrane in the middle and an inner Mucosal layer.
- Trial name
- NCT03569969
- Testing
- device: Tympanoplasty with Membrane Amniotic, Tympanoplasty With Autologous Fascia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mohammad Sadegh Bagheri Baghdasht
Conductive Hearing Loss, Perforated Tympanic Membrane
The Anatomic Determinants of Perforation Induced Hearing Loss
The purpose of this study is to identify factors that may contribute to conductive hearing loss. Conductive hearing loss is a type that is due to a problem with the outer or middle ear.
- Trial name
- NCT03271970
- Sponsor
- Duke University
Tympanic Membrane Perforation
Evaluation of Prognostic Factors in Tympanoplasty
Tympanoplasty is the surgical operation performed for the reconstruction of the eardrum and/or the ossicles. Tympanoplasty is classified into five different types, originally described by Horst Ludwig Wullstein.
- Trial name
- NCT03416725
- Testing
- Otoscope
- Volunteers
- 70 people
- Sponsor
- Assiut University
Tympanic Membrane Perforation
Eustachian Tube Function and Myringoplasty/Tympanoplasty
This study will determine whether the likely success of closing a hole in the eardrum can be predicted by testing Eustachian tube function.
- Trial name
- NCT01766856
- Testing
- Eustachian tube function testing
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Tympanic Membrane Perforation
Endoscopic Overlay Tympanoplasty for TM Perforation
Minimally invasive surgery is becoming more common in many surgical fields. The wide view of endoscope allows for minimally invasive transcanal approach instead of large postauricular opening.
- Trial name
- NCT02331797
- Testing
- Endoscopic Technique, Microscopic Technique
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Prince of Songkla University
Tympanic Membrane Perforation
A Study on the Regenerative Treatment of Tympanic Membrane With NPC-18 and FBG-18
To assess the efficacy and safety of the regeneration treatment of tympanic membrane with NPC-18 and FBG-18.
- Trial name
- NCT02550314
- Testing
- fiblast,gelatin sponge,fibrin glue
- Volunteers
- 20 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Perforation of Eardrum.
Tympanoplasty Using Conchal Cavum Approach and Conchal Pericondrium
Tympanoplasty -- conchal cavum approach is a modification of Heermann endural approach to repair broken eardrums. The Heermann approach is a well recognized procedure, in common clinical practise for years.
- Trial name
- NCT02000843
- Testing
- tympanoplasty -- conchal cavum approach
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Middle Ear Effusion, Tympanic Membrane Perforation
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers
PneuMum is a randomised controlled trial that aims to find out if pneumococcal vaccination for Australian Indigenous mothers, in the last few months of pregnancy or at delivery, can prevent ear disease in infants.
- Conditions
- Middle Ear Effusion, Tympanic Membrane Perforation, Acute Otitis Media, Pneumococcal Infections
- Trial name
- PneuMum (NCT00714064)
- Testing
- 23vPPV, dTpa (Pneumovax, Boostrix)
- Where
- Australia
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Tympanic Membrane Perforation
Fibrin Monomer Compared With Hemostatic Sponge in the Integrity of the Graft During Tympanoplasty
The diagnosis of tympanic perforation reaches a high number of records in otorhinolaryngology services worldwide. Most of the tympanoplasties are performed in patients whose cause of perforation and hearing loss was chronic…
- Trial name
- TISSUCOL (NCT02120651)
- Testing
- Fibrin monomer, Hemostatic sponge
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- CLOTILDE FUENTES OROZCO
Otitis Media
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Children
This clinical trial was conducted in a population where tympanic membrane perforation occurs in 60% infants in the first year of life.
- Trial name
- COMIT1 (NCT00539149)
- Testing
- Amoxycillin
- Where
- Australia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Middle Ear Effusion, Tympanic Membrane Perforation
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects Their Babies From Ear Disease
PneuMum is a randomised controlled trial that aims to find out if pneumococcal vaccination for Australian Indigenous mothers, in the last few months of pregnancy or at delivery, can prevent ear disease in infants.
- Conditions
- Middle Ear Effusion, Tympanic Membrane Perforation, Acute Otitis Media, Pneumococcal Infections
- Trial name
- NCT00310349
- Testing
- 23 valent pneumococcal polysaccharide vaccine
- Where
- Australia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Melbourne