Clinical trials: Tympanum; Perforation
Tympanic Membrane Perforation
Tympanoseal (Tympanic Membrane Device) Clinical Study
The purpose of this investigational study is to assess the ability of Tympanoseal (sodium/calcium alginate), an investigational device, to act as a scaffold during healing of the tympanic membrane.
- Trial name
- NCT02918942
- Testing
- Tympanoseal
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Grace Medical, Inc.
Tympanic Membrane Perforation, Eardrum Perforation
Biodesign® Otologic Repair Graft
The post-market follow-up clinical trial of the Cook® Biodesign® Otologic Repair Graft will follow patients up to 3 months post-implantation to determine the percent of patients with complete closure of the tympanic membrane.
- Trial name
- NCT04635228
- Testing
- Biodesign Otologic Repair Graft
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 87 people
- Sponsor
- Cook Research Incorporated
Chronic Tympanic Membrane Perforation
A Study to Assess ASP0598 Otic Solution Following Topical Application in the Ear in Subjects With Chronic Tympanic Membrane Perforation (CTMP)
The primary purpose of this study was to evaluate the safety and tolerability of ASP0598 Otic Solution. This study also evaluated the efficacy of ASP0598 otic solution.
- Trial name
- NCT04305184
- Testing
- ASP0598
- Where
- 10 sites in United States
- Volunteers
- 36 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Tympanic Membrane Perforation
Tympanoseal Clinical Study
The purpose of this investigational study is to assess the ability of Tympanoseal (sodium/calcium alginate), an investigational device, to act as a scaffold during healing of the tympanic membrane.
- Trial name
- NCT05849844
- Testing
- Tympanoseal
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Grace Medical, Inc.
Tympanic Membrane Perforation
Perf-Fix Study for Chronic Tympanic Membrane Repair
The purpose of the study is to assess the effectiveness of Perf-Fix as a gel patch to aid in the natural healing process to close chronic, >25% tympanic membrane perforation.
- Trial name
- NCT06083181
- Testing
- Perf-Fix Otologic Gel Patch
- Where
- 7 sites in United States
- Volunteers
- 71 people
- Sponsor
- Tympanogen