Clinical trials: Type 1 Diabetes, completed
Type 1 Diabetes
Continuous Glucose Sensing at the Site of Subcutaneous Insulin Administration
The study seeks to evaluate a novel treatment approach for performing continuous real-time glucose sensing and insulin delivery at the same subcutaneous tissue site.
- Trial name
- NCT02359617
- Testing
- insulin delivery, glucose sensing
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Type 1 Diabetes
Effects of Pre-Exercise Basal Insulin Manipulation on Glucose Dynamics in Females vs. Males With Type 1 Diabetes
The Purpose of the Study The purpose of this study is to compare how blood sugar levels change during exercise in men and women with type 1 diabetes (T1D).
- Trial name
- NCT07550608
- Testing
- 50% Pre-Exercise Basal Insulin Rate Reduction (BIRR), Habitual Basal Insulin Rate Maintenance
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Naama Constantini
Diabetes Mellitus, Type 2
A Study To Evaluate The Effects Of PF-05175157 In Healthy Volunteers
The primary purpose of this study is to evaluate pharmacodynamics of single oral doses of PF-05175157 in a dose-dependent fashion in healthy volunteers
- Trial name
- NCT01537497
- Testing
- PF-05175157
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabetes Mellitus, Type 1
CHO-loading Before and High Intermittent CHO-intake During Physical Exercise in T1D
Prolonged physical exercise (PE) is a challenge in type 1 diabetes with an increased incidence of both hypoglycemia and hyperglycemia.
- Trial name
- NCT03722225
- Testing
- Carbohydrate loading and high intermittent carbohydrate intake during physical exercise
- Volunteers
- 10 people
- Sponsor
- Örebro University, Sweden
Type 1 Diabetes
Closed-loop Glucose Control for Automated Management of Type 1 Diabetes
We hypothesize that our integrated closed-loop glucose-control system can provide effective, tight, and safe blood glucose (BG) control in type 1 diabetes, thereby establishing the feasibility of closed-loop BG control.
- Trial name
- NCT00811317
- Testing
- Closed-loop
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Type 1 Diabetes, Oxidative Stress
Role of Carnosine as an Adjuvant Therapy for Diabetic Nephropathy in Pediatrics With Type 1 Diabetes
Carnosine, a naturally-occurring dipeptide (β-alanyl-L-histidine) first described in 1900 by Gulewitsch and Amiradzibi, is found predominantly in post-mitotic tissues (e.g. brain and innervated muscle) of vertebrates .
- Conditions
- Type 1 Diabetes, Oxidative Stress, Carnosine, Diabetic Nephropathy
- Trial name
- NCT02928250
- Testing
- Carnosine
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Diabetes Mellitus, Type 1
A Meal Test Study of LY900014 in Participants With Type 1 Diabetes Mellitus
Two forms of insulin lispro (LY900014 and Humalog®) and two forms of insulin aspart (NovoRapid® and Fiasp®) will be given to trial participants with diabetes mellitus type 1 by injection under the skin.
- Trial name
- NCT03449433
- Testing
- LY900014, Insulin Lispro, Insulin Aspart
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes Mellitus, Pregnancy Related
Closed-loop Insulin Delivery In Type 1 Diabetes Pregnancies (CIRCUIT)
This trial will assess the efficacy of the Tandem t:slim X2 insulin pump with Control IQ technology compared with standard insulin delivery plus CGM in pregnant women with type 1 diabetes.
- Conditions
- Type 1 Diabetes Mellitus, Pregnancy Related, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- CIRCUIT (NCT04902378)
- Testing
- Tandem t:slim X2 insulin pump with Control IQ technology
- Where
- 14 sites in Australia, Canada
- Volunteers
- 94 people
- Sponsor
- University of Calgary
Type 1 Diabetes Mellitus
BMS - Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Dapagliflozin in Type 1 Diabetes
To obtain safety and tolerability information in patients with type 1 diabetes where Dapagliflozin is added on to Insulin (for 14 days)
- Trial name
- NCT01498185
- Testing
- Dapagliflozin
- Where
- 12 sites in United States
- Volunteers
- 171 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 1
Study to Test Efficacy of Real-time Reminders on Apple Watch To Decrease Late or Missed Meal Boluses
This will be a randomized, cross-over, unblinded study with subjects randomized upon entry into the study to either begin using the Klue software for 6 weeks or to continue with their usual care for 6 weeks.
- Trial name
- NCT03809858
- Testing
- Klue App
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Diabetes Type 1
National Epidemiological Study of the Possible Impact of Stress on Glycaemic Control in Patients With Type 1 Diabetes
The EPISTRESS2 study is a one-off cross-sectional epidemiological survey, carried out via an online form in patients with type 1 diabetes followed up by participating investigating centres.
- Trial name
- EPISTRESS2 (NCT06365255)
- Testing
- questionnaires
- Where
- 11 sites in France
- Volunteers
- 1,344 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Type 1 Diabetes Mellitus
An Evaluation of Internet-based Carbohydrate Counting Education for Adolescents With Type 1 Diabetes
Helping individuals with diabetes to control their blood sugars through self-management is an important goal, and counting carbohydrates (CHO) remains a key part of diabetes education and management.
- Trial name
- NCT02462785
- Testing
- In-person Carbohydrate Counting Class, Online Carbohydrate Counting Tutorial
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- The Hospital for Sick Children
Diabetes Mellitus
Safety and Efficacy of CLBS03 in Adolescents With Recent Onset Type 1 Diabetes (The Sanford Project T-Rex Study)
This clinical trial will explore the safety and effect of autologous ex vivo expanded polyclonal regulatory T-cells on beta cell function in patients, aged 8 to 17, with recent onset T1DM.
- Trial name
- NCT02691247
- Testing
- CLBS03 Low Dose, CLBS03 High Dose
- Where
- 15 sites in United States
- Volunteers
- 113 people
- Sponsor
- Lisata Therapeutics, Inc.
Type 1 Diabetes Mellitus
Pediatric Diabetics Type 1 Using InsuPatch
This study is a prospective, single-center, open label, randomized; two-arms cross over study. This is the test protocol for the InsuPatch device, whose purpose is to improve insulin delivery into the blood when the insulin is…
- Trial name
- NCT01368978
- Testing
- InsuPatch
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Insuline Medical Ltd.
Diabetes Mellitus, Type 1, Diabetes Mellitus
Investigating Genetic Risk for Type 1 Diabetes
The objective of this study is to determine the percentage of children with genetic markers putting them at increased risk of developing type 1 diabetes, and to offer the opportunity for these children to be enrolled into a phase…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- INGR1D (NCT03503747)
- Where
- United Kingdom
- Volunteers
- 15,640 people
- Sponsor
- University of Oxford
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
The Characteristics of Different Personal Lancets on Blood Volume and Perceived Pain in Patients With Diabetes Mellitus
A randomized single-blind study with the use of different lancing devices equipped with personal lancets to determine and to compare the amount of capillary blood volume and perceived pain after a single lancing of the fingertip.
- Trial name
- NCT04253431
- Testing
- Droplet lancing device (HTL-Strefa S.A.), Microlet 2 lancing device (Bayer), OneTouch Delicia lancing device (LifeScan)
- Volunteers
- 60 people
- Sponsor
- HTL-Strefa S.A.
Diabetes Mellitus, Type 1
Insulin Glulisine, Diabetes Mellitus Type 1
To provide local data on efficacy and safety of insulin glulisine in patients with Type 1 Diabetes Mellitus receiving insulin glargine as basic insulin therapy
- Trial name
- NCT00397553
- Testing
- Insulin glulisine
- Where
- Russia
- Volunteers
- 104 people
- Sponsor
- Sanofi
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Evaluation of Updated Continuous Glucose Monitoring (CGM) Form Factor in Adults, Adolescents and Pediatrics
The purpose of this study is to demonstrate the performance of the Disposable Sensor (DS5) in subjects age 2 - 80 years, for the span of 170 hours (7 days).
- Trial name
- NCT04436822
- Testing
- Continuous Glucose Monitoring
- Where
- 18 sites in United States, China
- Volunteers
- 317 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes Type 1
CGM Precision and Glycaemic Variability
Use of devices for continuous monitoring of the blood sugar is valuable for people with diabetes to understand their disease and to help prevent low blood sugar.
- Trial name
- NCT03842683
- Testing
- CGM
- Volunteers
- 472 people
- Sponsor
- Peter Vestergaard
Type 1 Diabetes Mellitus
Nutritional Intervention to Prevent Diabetes
Type 1 Diabetes (T1D) is an autoimmune disease. This means that the immune system (the part of the body which helps fight infections) mistakenly attacks and destroys the cells that produce insulin (islet cells found in the…
- Trial name
- TN06 (NCT00333554)
- Testing
- DHA Treatment
- Where
- 9 sites in United States
- Volunteers
- 99 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.