Clinical trials: Type 1 Diabetes, completed
Type 1 Diabetes
Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control
The protocol is a randomized clinical trial providing Multisystemic Therapy (MST), an intensive home-based family psychotherapy intervention, to a group of urban adolescents with poorly controlled Type 1 diabetes and their…
- Trial name
- NCT00519935
- Testing
- Multisystemic Therapy
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Wayne State University
Diabetes Mellitus, Type 2, Insulin Resistance
The Aging Endocrine Pancreas: Characterization of the Entero-insular Axis Physiology in the Elderly
Like most endocrine axes, the entero-insular axis is expected to go through an age-related physiological deterioration, what might contribute to special features of the elderly onset type 2 diabetes in comparison to middle-age.
- Trial name
- NCT00843479
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pain, Fear
Manual Pressure and ShotBlocker to Reduce Needle-Related Pain and Fear
This experimental, prospective, and randomized controlled study was designed to determine and compare the effects of applying manual pressure and ShotBlocker methods in reducing pain and fear during the subcutaneous insulin…
- Trial name
- NCT05789810
- Testing
- Manuel pressure, ShotBlocker, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Type1diabetes
Impact of the Continuous Measurement of Blood Glucose on Insulin Pump on Child Quality of Life With Type 1 Diabetes
The implementation of a sensor of glycemia Enlite coupled with an insulin pump (Medtronic Minimed 640G) is a therapeutic option that Hospital of Mulhouse can propose to the children affected by type 1 diabetes.
- Trial name
- IM-CAPT (NCT03177096)
- Testing
- Peds QL questionnaire and diabetes modulate, WHO-5 questionnaire, Felt questionnaire
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Type 1 Diabetes Mellitus
Aralast NP in Islet Transplant
Islet transplantation is a relatively new procedure used in people with difficult to control Type 1 diabetes. Insulin producing cells (islets) are isolated from a pancreas donated by the next of kin of a person who is brain dead.
- Trial name
- NCT02520076
- Testing
- Alpha-1 Antitrypsin
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of Alberta
Anxiety, Depression
Mindfulness-based Cognitive Therapy to Improve Emotional Wellbeing and Glycaemic Control in Diabetes
Type 1 and 2 diabetes are challenging conditions to manage. Anxiety and depression are common among this group and are associated with poorer diabetes control.
- Conditions
- Anxiety, Depression, Diabetes
- Trial name
- MILESTONE (NCT02600091)
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Aberdeen
Type1diabetes, Type1 Diabetes Mellitus
Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics
Investigators aim to further the understanding of environmental factors that underlie the progression to Type 1 diabetes (T1D). Dysbiosis, defined as alterations in intestinal microbiota composition and function, has been…
- Trial name
- NCT03423589
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Diabetic Nephropathies, Type 1 Diabetes Mellitus
Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing Haemodialysis
The purpose of the study is to assess the accuracy of the Dexcom G6 CGM system and the Abbott FreeStyle Libre flash system compared to the reference standard YSI (Yellow Spring Instruments) glucose in people with diabetes…
- Conditions
- Diabetic Nephropathies, Type 1 Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- ALPHA (NCT03885362)
- Testing
- Dexcom G6 and Abbott Freestyle Libre
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Closed Loop, Diabetes Mellitus, Type 1
Diabeloop for Teens
An open-label, three-centers, controlled, randomized, and crossover study containing 14 days of baseline period with standard of care (SOC) therapy followed by two-sessions of 4-weeks home study phase with Diabeloop closed-loop…
- Conditions
- Closed Loop, Diabetes Mellitus, Type 1, Adolescents (12 to 17 Years Old)
- Trial name
- DBL4T (NCT04725591)
- Testing
- Dexcom G6 Continuous Glucose Monitoring, MEDISAFE WITH External Insulin Pump, Diabeloop Software (Model predictive control)
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 49 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Type 1 Diabetes Mellitus
Single Hormone Closed Loop Study With PDT Sensor
The study described within this protocol is designed to test a single hormone closed-loop algorithm for managing blood glucose in type 1 diabetes using insulin only and a new device for measuring glucose continuously in the…
- Trial name
- NCT03528174
- Testing
- Artificial Pancreas Control system (APC), Pacific Diabetes Technologies CGM Insulin Infusion system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Primary Disease: 1. Type 2 Diabetes
Culinary Medicine vs. Nutrition Education in Diabetes
This pragmatic trial compares the effectiveness of virtual culinary medicine classes vs. standard of care medical nutrition visits to improve glycemic control in patients with uncontrolled type 2 diabetes .
- Trial name
- NCT05019274
- Testing
- Culinary Medicine Intervention, Standard of Care Nutrition Visits
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Type 1 Diabetes Mellitus
LEA29Y (Belatacept) Emory Edmonton Protocol
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- LEEP (NCT00468403)
- Testing
- Allogeneic Pancreatic Islet Cells, Belatacept, Basiliximab
- Where
- 2 sites in United States, Canada
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ocular Inflammatory Disease, Uveitis
Differences in Genes and Proteins in Active and Controlled Uveitis
This study will examine blood cells and other tissue samples from people with uveitis (eye inflammation) to try to gain a better understanding of this condition.
- Trial name
- NCT00357266
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Eye Institute (NEI)
Type 1 Diabetes
Parental Management of Young Children's Diabetes
Type 1 diabetes is a lifelong metabolic disorder that affects 1 out of every 400-600 American children each year, with many children being diagnosed at younger and younger ages.
- Trial name
- YCP (NCT00847327)
- Testing
- Parental Support, Diabetes Education
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes Mellitus
Continuous Subcutaneous Insulin Infusion Versus Multiple Dose Insulin Injections in Routine Clinical Practice
Observational study about effectiveness and safety of continuous subcutaneous insulin infusion compared to multiple dose insulin injections in Type 1 Diabetes Mellitus (T1DM) adult patients in routine clinical practice.
- Trial name
- real-ECIMI (NCT03793283)
- Testing
- CSII, Multiple dose insulin injections
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Castilla-La Mancha Health Service
Arterial Stiffness in Youth With Type 1 Diabetes
Arterial Stiffness in Type I Diabetes Mellitus
Using radial artery tonometry to study arterial stiffness, the plan is to study a cohort of 65 children with Type I diabetes mellitus.
- Trial name
- NCT02218268
- Testing
- Pre-meal bolus, No meal bolus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Diabetes Mellitus, Type 1
A Study of Insulin Peglispro and Glargine on Fats in Participants With Type 1 Diabetes
This study has two parts. Each participant will receive a daily injection of insulin peglispro during one treatment period and a daily injection of insulin glargine during the other treatment period.
- Trial name
- NCT01771250
- Testing
- Insulin Peglispro, Insulin Glargine
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes Mellitis
Neurocognitive Impact of Hypoglycemia in Type 1 Diabetes
125 children with Type 1 Diabetes mellitis (T1DM) between 4 and 16 were recruited and 62 healthy siblings also enrolled in the study.
- Trial name
- HYPO (NCT00916838)
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Type 1 Diabetes
Association of Type 1 Diabetes Mellitus in Offsprings With Positive Parental History of Diabetes
Primary Objective: To measure the association between a parental history of diabetes and the odds of an offspring being Type 1 diabetics. Secondary Objectives: To document the profile of Type 1 diabetes patients.
- Trial name
- SHINE (NCT03312478)
- Testing
- Blood draw for insulin auto-anti body tests*
- Where
- Pakistan
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Sanofi
Type 1 Diabetes
Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin
Most of the studies concerning aerobic fitness in Type 1 diabetic patients noted a relationship between impaired aerobic fitness and high glycated haemoglobin (HbA1c) levels, reflecting poor long term glycaemic control.
- Trial name
- OXYDIAB (NCT02051504)
- Testing
- Incremental maximal exercise, Oral Glucose Tolerance Test, Muscle biopsy
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
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