Clinical trials: Type 1 Diabetes, completed
Type 1 Diabetes Mellitus
Low Carbohydrate Diet, Glycaemic Control and Quality of Life in Australian Adults With Type 1 Diabetes
The aim of this study is to examine the association between a low carbohydrate diet, quality of life and glycaemic control in Australian adults with T1DM.
- Trial name
- NCT04213300
- Testing
- Low carbohydrate diet
- Where
- Australia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Gold Coast Hospital and Health Service
MODY1, MODY3
Glucagon in MODY (Maturity Onset Diabetes of the Young)
The aim of this study is to determine whether fasting and post-prandial glucagon secretion is suppressed by gliclazide in patients with HNF1-/4-alpha MODY.
- Trial name
- NCT03246828
- Testing
- Omission of gliclazide
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Oxford
Type 1 Diabetes
Evaluation of Gut Absorption Rate of Glucose After a Large Evening Meal in Type 1 Diabetes
Eight adolescent and young adult subjects with type 1 diabetes, age 16-24 years, will be recruited for this study on the basis of informed consent.
- Trial name
- NCT02782195
- Volunteers
- 16 people
- Sponsor
- University of Cambridge
Diabetes Mellitus, Type 2
Pharmacokinetic Profile of Two Formulations of PB1023 Following Single Subcutaneous Injection in Subjects With Type 2 Diabetes Mellitus
Primary objective: To compare the pharmacokinetic profile of PB1023 after a single dose administered by subcutaneous injection of two formulations (concentrations).
- Trial name
- NCT01427257
- Testing
- Single Dose PB1023
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- PhaseBio Pharmaceuticals Inc.
Type 1 Diabetes
Adherence to Guidelines VAccination in Type 1 DIabetes Mellitus Patients (AVADI-2)
Observational study about adherence to guidelines for Covid-19, Influenza, Pneumococcal and Hepatitis B Vaccination in adult patients with type 1 Diabetes mellitus.
- Trial name
- AVADI-2 (NCT05481801)
- Testing
- Covid-19 vaccination, Influenza vaccination, Pneumococal vaccination
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Castilla-La Mancha Health Service
Type 1 Diabetes
Closed-loop Control of Overnight Glucose Levels (Artificial Pancreas) in Type 1 Diabètes Adults With Hypoglycemia Unawareness and Documented Nocturnal Hypoglycemia
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT02282254
- Testing
- Overnight intervention
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes Mellitus
The Effect of Probiotics on Type 1 Diabetes Mellitus in Children
In this study, investigators try to administer probiotics (Lactobacillus salivarius + Lactobacillus johnsonii + Bifidobacterium lactis from glac biotech Co., Ltd.) to children T1DM patients for 6 months to observe if the…
- Trial name
- NCT03880760
- Testing
- L. johnsonii MH-68, B. animalis subsp. lactis CP-9 and L. salivarius AP-32
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- China Medical University Hospital
Diabetes Mellitus, Type 1
A Research Study Looking at How Faster Aspart Injected in Double Concentration Works in the Body of People With Type 1 Diabetes Mellitus
This study is looking at how five different formulations of faster aspart 200 U/mL reach and stay in the blood after injection. The purpose is to find a formulation that behaves similarly to the reference product called faster…
- Trial name
- NCT03723759
- Testing
- Faster Aspart 200 U/mL, Faster aspart 100 U/mL
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus Type 1 and 2, Diabetes Mellitus Complications
Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis
The purpose of this study is to evaluate the pharmacodynamic (PD) and pharmacokinetic (PK) profile and the safety and tolerability of RM-131 in patients with diabetes mellitus and delayed gastric emptying.
- Conditions
- Diabetes Mellitus Type 1 and 2, Diabetes Mellitus Complications, Gastroparesis, Gastrointestinal Motility Disorder
- Trial name
- NCT01394055
- Testing
- RM-131
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Motus Therapeutics, Inc.
Diabetes, Diabetes Mellitus, Type 1
Observational Study With InnoLet® in Daily Clinical Practice
This study is conducted in Asia. The aim of this study is to review the efficacy and safety of insulin treatment with InnoLet® in daily clinical practice.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01492959
- Testing
- insulin human
- Where
- South Korea
- Volunteers
- 1,030 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 1
Blood Glucose Awareness Training for Parents
The purpose of this study is to test a training program for parents of children with T1DM.
- Trial name
- NCT00315991
- Testing
- Blood Glucose Awareness Training for Parents
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of Virginia
Diabetic Peripheral Neuropathy
Safety and Efficacy of CBX129801 in Patients With Type 1 Diabetes
The purpose of the study is to determine the beneficial effects of CBX129801 (PEGylated synthetic human C-peptide) following weekly subcutaneous administration for 12 months in type 1 diabetes mellitus patients (T1DM) with mild…
- Trial name
- NCT01681290
- Testing
- CBX129801
- Where
- 29 sites in United States, Canada and 1 more
- Volunteers
- 250 people
- Sponsor
- Cebix Incorporated
Diabetic Peripheral Neuropathy
Safety Study of Intranasal Insulin in Type 1 Diabetes and Diabetic Peripheral Neuropathy
The aim of this study is to evaluate the safety and tolerability of intranasal insulin in people with type 1 diabetes and diabetic peripheral neuropathy and to determine whether intranasal insulin is effective in slowing the…
- Trial name
- IIDPN (NCT01469559)
- Testing
- Novolin Toronto insulin, Normal saline
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Insulin Dependent Diabetes Mellitus 1
Longevity of Multi-Slitted Catheter With Lantern Technology
To determine time to set failure when the Convatec Inset II with Lantern technology (Convatec Lantern) infusion set with multi-slitted catheter is worn for up to 10 days
- Trial name
- Lantern (NCT03819634)
- Testing
- Inset II with Lantern Technology
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Type1diabetes
Self Efficacy Levels, Attachment Style and Resiliency of Youth With Type 1 Diabetes
This project will assess self-efficacy levels(SE) ,resiliency and attachment style of adolescent with type 1 diabetes and their caregivers.SE and attachment style of patients and parents will be compared with each other as well…
- Trial name
- NCT04172077
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- The Hospital for Sick Children
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate Safety of Levemir® in Type 1 and Type 2 Diabetes
This study is conducted in Asia. The aim of this observational study is to evaluate the incidence of adverse events while using Levemir® under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00700765
- Testing
- insulin detemir
- Where
- Indonesia
- Volunteers
- 1,531 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes, Sleep Apnea Syndrome
Effect of Sleep Apnea Treatment on Type 1 Diabetes
Hypothesis: To address the role of continuous positive airway pressure (CPAP)on nocturnal glycemia in patients having type 1 diabetes and sleep apnea syndrome.
- Trial name
- DIADEME (NCT02316665)
- Testing
- continuous positive airway pressure
- Where
- France
- Volunteers
- 81 people
- Sponsor
- University Hospital, Grenoble
Diabetes, Type 1 Diabetes
The Effects of Alpha-1 Antitrypsin (AAT) on the Progression of Type 1 Diabetes
The purpose of this study is to determine if the drug Alpha-1 Antitrypsin (AAT, Aralast NP) will preserve beta-cell function and help slow the progression of type 1 diabetes.
- Trial name
- NCT01319331
- Testing
- Alpha 1-Antitrypsin (AAT, Aralast NP)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Colorado, Denver
Non-Insulin-Dependent Diabetes Mellitus
AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes
This study compares the effects of Avandamet (rosiglitazone maleate/metformin) treatment and metformin plus sulphonylurea treatment in overweight people with type 2 diabetes.
- Trial name
- NCT00359112
- Testing
- metformin, sulphonylurea, Avandamet
- Where
- 142 sites in Belgium, France and 9 more
- Volunteers
- 544 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 1, Carbohydrates
Carbohydrate Estimation Supported by the GoCARB System
The standard method for determining the carbohydrate content of a meal in patients with diabetes mellitus is the weighing of individual foods. However, in daily life, the weighing is not practical at all times.
- Trial name
- NCT02546063
- Testing
- Smartphone App
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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