Clinical trials: Type 1 Diabetes, completed
Type 1 and 2 Diabetes
Genetic Polymorphisms, Steatosis and Diabetes
Our research hypothesis is to show that a certain number of genetic polymorphisms of the proteins involved in glucose, lipid and adipocyte metabolism are factors that favour the development of steatosis in patients with Type 2…
- Trial name
- NCT02045563
- Testing
- prise de sang, magnetic resonance imaging and magnetic resonance spectroscopy
- Where
- France
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Type 1 Diabetes, Pregnancy, High Risk
Intravenous Insulin vs Subcutaneous Insulin Infusion in Intrapartum Management of Type 1 Diabetes Mellitus
The purpose of this study is to perform a randomized trial to investigate if intrapartum insulin delivery mechanisms reduces adverse outcomes associated with type 1 diabetes in pregnancy.
- Trial name
- NCT04599075
- Testing
- Insulin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Gianna Wilkie
Type 2 Diabetes Mellitus
An Exploratory Study of the Effects of Trelagliptin and Alogliptin on Glucose Variability in Patients With Type 2 Diabetes Mellitus
This is a multi-center, randomized, open-label, parallel-group comparative, exploratory study to evaluate the effect of trelagliptin administered at a dose of 100 mg once weekly or alogliptin administered at a dose of 25 mg once…
- Trial name
- TRACK (NCT02771093)
- Testing
- Trelagliptin, Alogliptin
- Where
- Japan
- Volunteers
- 27 people
- Sponsor
- Takeda
Marathon, Physical Activity
Glycemic Control Before, During and After the 2016 Paris Marathon
This is an observational mono-centric retrospective study carried out at the University Hospital of Brest The main objective of this study is to assess the glycemic control before, during and after the 2016 Paris Marathon in…
- Conditions
- Marathon, Physical Activity, Type 1 Diabetes Mellitus, Education
- Trial name
- MARADIAB (NCT04926298)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Type I Diabetes
Obesity and Metabolic Surgery in Patients With Type I Diabetes
Obesity is the indication for bariatric surgery in type I diabetes. Interestingly postsurgery the patients improve remarkable in their need for insulin, not only in the daily total insulin dosage but also in the dosage of IU per…
- Trial name
- NCT02612493
- Testing
- Obese patients with type I diabetes
- Volunteers
- 16 people
- Sponsor
- Sana Klinikum Offenbach
Diabetes Mellitus, Type 1
Comparison of Hepatic Directed Vesicle (HDV)-Insulin Lispro Versus Insulin Lispro to Further Improve Glycemic Control
Multi-Center, double blind, active comparator controlled multiple dose safety, tolerability and efficacy study
- Trial name
- NCT03096392
- Testing
- HDV insulin lispro 100 UNT/ML, Insulin Lispro 100 UNT/ML
- Where
- 5 sites in United States
- Volunteers
- 46 people
- Sponsor
- Diasome Pharmaceuticals
Type 2 Diabetes Mellitus, Postprandial Hyperglycemia
Effects of Insulin Treatment on Postprandial Platelet Activation in Patients With Non-insulin-dependent Diabetes Mellitus (NIDDM)
The postprandial phase in diabetic patients is characterized by a rapid increase in blood glucose levels, increase in platelet aggregation, LDL oxidation and over production of thrombin.
- Trial name
- NCT00771693
- Testing
- Insulin aspart (Novorapid®)
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Diabetes Mellitus, Type 2
Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus
Primary objective: To evaluate the safety and tolerability of single and multiple ascending doses of PB1023 administered as a subcutaneous (SC) injection in adult subjects with T2DM. Secondary objectives: 1.
- Trial name
- NCT01236404
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- PhaseBio Pharmaceuticals Inc.
Diabetes Mellitus, Macular Edema
Laser and Medical Treatment of Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00027287
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Eye Institute (NEI)
Hypoxia, Diabetes Mellitus, Type 1
Studies on the Adaptive Responses to Hypoxia
The general aim of this study is to define the response to hypoxic challenge in patients with diabetes. The investigation will provide response for different questions that are central for explaining the development of…
- Trial name
- HYKRAND (NCT02629406)
- Testing
- Hypoxia
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Type 1 Diabetes, Quality of Life
Randomized Crossover Study to Test the Impact of Using a Software for Smartphones and Tablets in Treating Type 1 Diabetes
The purpose of this study is to evaluate the impact of a software for smartphones and tablets on type 1 diabetes control and quality of life
- Conditions
- Type 1 Diabetes, Quality of Life, Hypoglycaemia
- Trial name
- NCT02107326
- Testing
- Webdia Software
- Where
- Switzerland
- Volunteers
- 55 people
- Sponsor
- Philippe Klee
Type 2 Diabetes Mellitus
A Multicenter, Open Label, Single Dose Study to Evaluate the Effect of Renal Insufficiency on the Pharmacokinetics of SK 0403
This is a Phase 1, multicenter, open label, single dose study. A total of 30 subjects are planned (5 groups of 6 subjects each.)
- Trial name
- NCT01131091
- Testing
- SK-0403
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kowa Research Institute, Inc.
Celiac Disease, Diabetes Mellitus, Type 1
Celiac Disease and Diabetes- Dietary Intervention and Evaluation Trial
Currently no consensus exists on the optimal way to manage asymptomatic patients with celiac disease (CD) and Type 1 diabetes (T1D).
- Trial name
- CD-DIET (NCT01566110)
- Testing
- Gluten Free Diet
- Where
- 7 sites in Canada
- Volunteers
- 50 people
- Sponsor
- The Hospital for Sick Children
Diabetes, Type I
A Randomised, Single Centre, Double-Blind, Two-Period Crossover, Glucose Clamp Trial
Clinical pharmacology trials investigating insulin detemir in subjects with type 1 diabetes have shown a prolonged and reproducible action profile of insulin detemir compared with NPH insulin and insulin glargine.
- Trial name
- ENM-HS-001 (NCT00810589)
- Testing
- Levemir, Humalog NPL Insulin
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Type 1
Use of a Telehomecare Program for Young Patients With New Onset Type 1 Diabetes
In a Pediatric University Teaching Hospital in Montreal, an Intelligent Distance Patient Monitoring Program was developed to allow for: Automatic download of blood glucose levels Automatic alerts indicating hypoglycemias…
- Trial name
- NCT01401790
- Testing
- Telehomecare (Intelligent Distance Patient Monitoring), Standard education and follow up at diabetes clinic
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Huot, Celine, M.D.
Hypoglycemia, Diabetes Mellitus, Type 1
A Trial to Compare the Efficacy and Safety of 2 Different Batches of Subcutaneous Dasiglucagon in Patients With T1DM
A randomized, double-blind, crossover trial to compare the efficacy and safety of 2 different batches of subcutaneous dasiglucagon in patients with type 1 diabetes mellitus (T1DM)
- Trial name
- NCT03895697
- Testing
- dasiglucagon
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Zealand Pharma
Diabetes Mellitus, Type 1
Influence of Binge Drinking on Glucose Metabolism in Patients With Type 1 Diabetes - A Pilot Study
Although there is no evidence that individuals with type 1 diabetes have a different approach to alcohol compared to the background population, nevertheless, its use does have implications for patients mainly because of the risk…
- Trial name
- NCT00135915
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- The Royal Bournemouth Hospital
Diabetes Mellitus, Type 1
Randomized Trial to Assess Efficacy and Safety of Continuous Glucose Monitoring in Children 4-<10 Years With T1DM
The purpose of this study is to determine the efficacy, tolerability, safety, and effect on quality of life of CGM in children 4 to less than 10 years of age with type 1 diabetes.
- Trial name
- NCT00760526
- Testing
- Continuous glucose monitor, Home blood glucose monitor
- Where
- 5 sites in United States
- Volunteers
- 146 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes
Liraglutide in Type 1 Diabetes
The glucose lowering effects of GLP-1 agonists are well established in subjects with type 2 diabetes, however, these have not been studied prospectively in subjects with type 1 diabetes.
- Trial name
- 1966 (NCT01722240)
- Testing
- Liraglutide 1.8mg
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Type 2 Diabetes Mellitus, Steroids
Incretin Physiology Associated With Steroid Hormone Treatment
The purpose of this study is to evaluate whether the reduced incretin effect and the paradoxical glucagon responses during oral glucose ingestion and isoglycaemic iv glucose infusion observed in patients with type 2 diabetes are…
- Trial name
- NCT00713440
- Testing
- Oral glucose test (OGTT); isoglycaemic iv. clamp; liquid meal test; Gastric Emptying Rate; Prednisolone; Paracetamol
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
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