Clinical trials: Type 1 Diabetes, completed
Type 1 Diabetes Mellitus
Bolus Calculator and Wireless Communication With Blood Glucose Meter in Management of Type 1 Diabetes Mellitus (T1DM).
Bolus calculator (BC) is one of the advanced functions in modern insulin pumps (CSII)models. Together with wireless communication with blood glucose meter potentially facilitates achieving the target post prandial glucose levels.
- Trial name
- NCT01677546
- Testing
- CSII+BC+CL, CSII+BC
- Where
- Poland
- Volunteers
- 156 people
- Sponsor
- Medical University of Warsaw
Telenursing, Adolescent
Tele Nursing Application For Type 1 Diabetes Mellitus Adolescents
Studies have shown that tele-nursing practice is effective in children with Type 1 Diabetes Mellitus, but the number of studies conducted is very few.
- Conditions
- Telenursing, Adolescent, Type 1 Diabetes Mellitus
- Trial name
- NCT05211479
- Testing
- educational intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- University of Yalova
Type 1 Diabetes Mellitus
Effect of Closed Loop Glucose Control on Exercise-Associated Hypoglycemia
The purpose of the study is to compare the glycemic control during and following aerobic exercise using either an open or closed-loop insulin delivery system.
- Trial name
- ePID-03 (NCT00831389)
- Testing
- Closed Loop
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 2 Diabetes Mellitus
Feasibility of Once/Daily Administered GLP/1 Receptoragonist (Lixisenatide) in Combination With Basal Insulin
Premixed insulin-based therapy is a standard insulin treatment strategy in Austria. The widespread use of premixed insulin is explained by high acceptance by health care professionals and patients due to one single product and…
- Trial name
- LixiBIT (NCT02168491)
- Testing
- Lixisenatide, Insulin glargine
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Type 1 Diabetes
Carbohydrate Counting in Children and Adolescents With Type 1 Diabetes
The total amount of carbohydrates (CHO) at meal consumed strongly predicts the glycemic response in children and adolescents with type 1 diabetes.
- Trial name
- NCT02350374
- Testing
- carbohydrate counting
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Fondation Lenval
Diabetes Mellitus
First Clinical Evaluation of a Novel Glucose Non-invasive Sensor Technology in Patients With Type 1 Diabetes
The primary aim of this clinical study is to find signal characteristics of VOCs detected by Sokru device during fasting, insulin injection and after glucose intake and to find the association with blood glucose variation in…
- Trial name
- VAARA (NCT05771090)
- Testing
- Sokru device
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- DCB Research AG
Type 1 Diabetes
Closing the Loop in Adults With Type 1 Diabetes Under Free Living Conditions (AP@Home04_Phase 4)
The main objective of this study is to determine whether home use of day and night closed loop insulin delivery under free living conditions applying ultra-rapid insulin lispro (Lyumjev) is superior to home use of closed-loop…
- Trial name
- NCT05257460
- Testing
- Hybrid closed-loop using ultra-rapid insulin lispro, Hybrid closed-loop using standard insulin lispro
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Cambridge
Diabetes Mellitus Type 1
Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients
This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated.
- Trial name
- NEURODIAB1 (NCT02538120)
- Testing
- Microvascular assessment
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Diabetes Mellitus, Type 1
Safety and Efficacy of Empagliflozin (BI 10773) in Type 1 Diabetes Mellitus Patients With or Without Renal Hyperfiltration
This open-label study aims to evaluate the impact of BI 10773 treatment on glomerular filtration rate under controlled conditions of euglycaemia and hyperglycaemia in subjects with type 1 diabetes mellitus with or without renal…
- Trial name
- NCT01392560
- Testing
- BI 10773
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Boehringer Ingelheim
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Safety and Parameters of Application Technique
This study is conducted in Europe. The aim of the study is to monitor patients changing therapy from syringe to insulin delivery system as prescribed by the treating physician in Slovakia.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Delivery Systems
- Trial name
- NCT01516242
- Testing
- No treatment given
- Where
- Slovakia
- Volunteers
- 4,819 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects
The study is being performed to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) properties of single oral doses of DBPR108 in healthy male subjects.
- Trial name
- NCT01650324
- Testing
- DBPR108
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Type 1 Diabetes
A Pilot Study to Evaluate the Safety of Terbutaline in Children With Type 1 Diabetes
The purpose of the study is to gain experience with the use of terbutaline in children with T1D and to determine that there is not a frequent serious, unexpected, uncontrollable effect on short-term glycemic control.
- Trial name
- NCT00607503
- Testing
- Terbutaline
- Where
- 6 sites in United States
- Volunteers
- 9 people
- Sponsor
- Jaeb Center for Health Research
Diabetes, Diabetes Mellitus, Type 2
Observational Study of Glycaemic Control in Patients Uncontrolled on Oral Antidiabetic Agents and Starting With 1 (Once) Daily Levemir® (Insulin Detemir) as the Treatment of Type 2 Diabetes Mellitus
This study is conducted in Europe. An observational study evaluating glycaemic control in patients using Levemir® as initiation insulin therapy as the treatment of type 2 diabetes in Slovakia.
- Trial name
- START (NCT00687284)
- Testing
- insulin detemir
- Where
- Slovakia
- Volunteers
- 2,188 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 1
Avoidance of Hyperglycaemia in People With Type 1 Diabetes
This study aims to learn more about avoidance of hyperglycaemia in adults with type 1 diabetes. People who attend a type 1 diabetes clinic will be invited to complete a number of self-report questionnaires and a survey.
- Trial name
- HYPE (NCT04732780)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- Imperial College London
Diabetes Mellitus, Type 1, Arrhythmia
Cardiovascular Effects of Exercise-related Hypoglycaemia in Patients With Type 1 Diabetes (Hypo Heart Exercise)
Patients with type 1 diabetes are recommended to perform at least 150 minutes of accumulated physical activity each week, however fear of hypoglycaemia is a well-known barrier to exercise in these patients.
- Trial name
- NCT04650646
- Testing
- Exercise-related hypoglycaemia, Hypoglycaemia under resting conditions
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Type 1 Diabetes Mellitus
The Safety and Efficacy of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With T1DM
This study will enroll eligible subjects into a long-term safety study (Part B). Japanese male and female patients with T1DM and age 18 to 75 years, with inadequate glycemic control on insulin defined as HbA1c ≥ 7.5% and ≤ 10.5%…
- Trial name
- NCT02582814
- Testing
- Dapagliflozin 5 mg, Dapagliflozin 10mg
- Where
- 24 sites in Japan
- Volunteers
- 151 people
- Sponsor
- AstraZeneca
Type 1 Diabetes
MD-Logic Artificial Pancreas for Automatic Type 1 Diabetes Meals Management
The MDLAP (MD-Logic Artificial Pancreas)system is as an automatic system to regulate glucose levels by delivery of insulin operable in clinical trial settings.
- Trial name
- NCT01901913
- Testing
- MD-bolus calculator for pre-meal bolus, No MD-bolus calculator for pre-meal bolus
- Where
- Israel
- Volunteers
- 26 people
- Sponsor
- Rabin Medical Center
Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM)
Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED
The goal of this clinical trial is to improve the processes of Type 2 Diabetes (T2D) care coordination and treatment in the emergency department (ED) by utilizing clinical decision support mechanisms in the electronic health…
- Conditions
- Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM), Hyperglycemia, Insulin Dependent Diabetes
- Trial name
- DEPICCT (NCT06899191)
- Testing
- Hemoglobin A1c, Observation Unit
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Rutgers, The State University of New Jersey
Type 1 Diabetes
Hybrid Closed Loop in High Risk Youth With Type 1 Diabetes
The use of insulin pumps and continuous glucose monitors for Type 1 diabetes (T1D) has been shown to improve glycemic control while also decreasing the risk for acute and chronic complications.
- Trial name
- NCT04807374
- Testing
- Control IQ
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's National Research Institute
Type 1 Diabetes, Insulin Pump Therapy
MD Logic Pump Advisor- Adults Study
Prospective, randomized, controlled, 30-78 days trial comparing MD-Logic pump algorithm to the standard of care of patients with type 1 diabetes.
- Trial name
- NCT01157923
- Testing
- MD Logic Pump Advisor
- Where
- 2 sites in Israel, Slovenia
- Volunteers
- 18 people
- Sponsor
- Rabin Medical Center
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