Clinical trials: Type 1 Diabetes
Diabetes Mellitus, Type 1
Family Management of Type 1 Diabetes in Children
This is a multi-center, randomized controlled trial to test whether a clinic-integrated, low intensity, multi-component behavioral intervention is effective in preventing the deterioration in glycemic control, treatment…
- Trial name
- NCT00273286
- Testing
- family diabetes management intervention
- Where
- 4 sites in United States
- Volunteers
- 422 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diabetes Insulin Dependent
Evaluation of Interests of FIT Therapy on Diabetics Children Insulin-dependent
Evaluation of interests of the functional insulin therapy (FIT Therapy) on metabolic control, hypoglycemia prevention and life quality of diabetics children insulin-dependent treated with insulin pump.
- Trial name
- DIABFIT (NCT01443741)
- Testing
- Therapeutic education
- Where
- 6 sites in France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Angers
Type 1 Diabetes
Long Term Effects of Diabetes of Very Young Children
To investigate neurocognitive and behavioral measures in 25 children aged 6-10 years diagnosed with diabetes for > 5 years who have received long-term insulin pump therapy (> 3 years) compared to a group of children matched for…
- Trial name
- NCT00707629
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Diabetes Mellitus, Type 2
Effect of Exenatide LAR or Dulaglutide on the Variability of 24-hour Heart Rate and Blood Pressure in Type 2 Diabetes
Mortality due to cardiovascular problems is increased by having Diabetes Mellitus type 2 (DM2), related to the time of evolution and glucose levels or if alterations in blood pressure coexist.
- Trial name
- NCT03444142
- Testing
- Exenatide LAR, Dulaglutide
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- University of Guadalajara
Type 2 Diabetes Mellitus
A Study of ASP1941 in Japanese Patients With Type 2 Diabetes Mellitus
The primary purpose of this study is to evaluate the pharmacodynamic profile (blood glucose and urinary glucose excursion) of ASP1941 in patients with type 2 diabetes mellitus.
- Trial name
- NCT01023945
- Testing
- ASP1941
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Astellas Pharma Inc
Type 1 Diabetes Mellitus
Doppler Ultrasound Investigation of Microcirculations
The investigators aim to show that quantitative analysis of doppler flow velocity waveforms i.e. ultrasound which is a non-invasive and very safe means of assessing blood flow; recorded in the proximity of terminal microvascular…
- Trial name
- NCT01045005
- Testing
- Administration ofOxygen and carbon dioxide, Administration of Oxygen and carbon dioxide
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Type1 Diabetes, Adolescents
Real-world Use of Hybrid Closed Loop in Adolescents and Young Adults 15-25 Years of Age with Type 1 Diabetes
The purpose of this study is to determine the effect of hybrid closed loop on glycemic outcomes in young patients aged between 15 and 25 years old with type 1 diabetes, whatever is their initial metabolic control.
- Conditions
- Type1 Diabetes, Adolescents, Young Adults
- Trial name
- BFHado (NCT06253351)
- Testing
- Hybrid closed loop (HCL)
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Sud Francilien
Type 2 Diabetes Mellitus
Single Cohort 4-period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine
The purpose of this study is to evaluate the effect of steady-state ranolazine on the steady state PK of metformin in subjects with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01546597
- Testing
- Metformin, Ranolazine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Gilead Sciences
Type1 Diabetes Mellitus
Proof of Concept - Identification of Patient-specific Parameters for Bolus Calculators for Type 1 Diabetes
The adoption of bolus calculators has been limited by the slow speed of the current trial and error approach. The goal of this project is to automate the determination of patient specific insulin pump parameters based on current…
- Trial name
- POC-IDENTITY-1 (NCT03414320)
- Testing
- Gathering data
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
type1diabetes, Hunger
Postprandial Gut Hormone Responses in Patients With Type 1 Diabetes Mellitus
The study will compare the postprandial responses to a test meal between subjects with type 1 diabetes and healthy control subjects, in terms of gut hormone levels, meal induced thermogenesis, hunger and satiety perception, as…
- Conditions
- type1diabetes, Hunger, Obesity
- Trial name
- NCT04430946
- Testing
- Standardized test meal
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Impacts of Glucose Forecasting
This is a study of individuals with type I or type II diabetes. It is meant to test the effect of using the Diabits app on a participant's blood glucose control.
- Trial name
- NCT04217369
- Testing
- Diabits Predictions
- Volunteers
- 90 people
- Sponsor
- Bio Conscious Technologies Ltd
Type 1 Diabetes Mellitus
A Study to Evaluate Symlin in Adolescent Subjects With Type 1 Diabetes Mellitus
This study will be the first evaluation of Symlin in adolescent subjects with type 1 diabetes mellitus and is designed to evaluate the blood levels (pharmacokinetics), biochemical and physiological effects (pharmacodynamics), and…
- Trial name
- NCT00313183
- Testing
- pramlintide acetate
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- AstraZeneca
Diabetes Mellitus Type 1
A Study Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections With Insulin Lispro and Glargine
This trial will compare the metabolic control in type 1 diabetes obtained by continuous infusion of insulin lispro with that obtained by multiple daily injections of insulin lispro and glargine, a long-acting insulin analogue.
- Trial name
- NCT00468754
- Testing
- Insulin pumps
- Where
- 4 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Hoffmann-La Roche
Diabetes Mellitus, Type 1
Long-term, Implantable Sensor Improves Health Outcomes in Patients With T1D
The implantable Eversense ® CGM System obtained CE marking in 2016 for the 90-day device and in 2017 for the 180-day device.There is interest in real-world clinical evidence on the use of Eversense regarding changes in HbA1c and…
- Trial name
- NCT04160156
- Testing
- Long term sensor
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Magna Graecia
Diabetes Mellitus, Type 1
Improving HbA1c Levels Through Behavioural Change of Diabetes Self-management Assisted by the LovedBy Mobile Application for Young Adults and Adolescents With Type 1 Diabetes
Young people (16-25) with type-1 diabetes have historically struggled with managing their condition. Typically, the average HbA1c levels are significantly higher and as such, the risk of long term complications tend to be far…
- Trial name
- LBY-T1 (NCT05217953)
- Testing
- LovedBy App
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Diabetes Type 1
Multicenter Study Evaluating the Relationship Between Perceived Daily Stress Level and Glycemic Level in Subjects With Type 1 Diabetes
Type 1 diabetes (T1D) affects around 200,000 people in France. The only treatment is insulin, administered either by multiple injections, by pump alone or, more recently, by automated insulin delivery systems (AIDs), which have…
- Trial name
- EVASTRESS (NCT06896045)
- Testing
- Assess stress levels 4 times a day before meals (morning, noon and evening and at bedtime) using a visual analogue scale
- Where
- 14 sites in France
- Volunteers
- 125 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Hepatomegaly
Prevalence of Hepatomegaly in Children and Adolescents With Type 1 Diabetes Mellitus
To assess the prevalence of hepatomegaly in children and adolescents with type 1 diabetes mellitus, and to find out it᾿s underlying etiology.
- Trial name
- NCT03666117
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Type 1 Diabetes
Effect of the InsuPatch on Automated Closed-loop Glucose Control in Type 1 Diabetes
This research study designed to look at how well adolescents' and young adults' blood sugars can be controlled with a "closed loop artificial pancreas" using a continuous glucose sensor, an insulin pump, and a computer program…
- Trial name
- IPCL (NCT01787318)
- Testing
- ePID closed loop system, InsuPatch
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Diabetes Mellitus, Type 1
AbATE Follow-Up Study
This study proposes to conduct a non-interventional, multi-center trial that will look at C-peptide results from one or two Mixed Meal Tolerance Tests (MMTT) in participants who received anti-CD3 treatment or placebo on the Abate…
- Trial name
- NCT02067923
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW III Asia Registry Orsiro Stent System
Cliflical evaluation of th' Orsiro LESS 10 diabetic subjects requiring coronary revasculariza t ion with Drug Eluting Stefl ts (DES) .880 subjects will be enrolled in this registry.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Diabetes Mellitus Type 1 or 2
- Trial name
- NCT01941290
- Where
- 19 sites in China, India and 3 more
- Volunteers
- 387 people
- Sponsor
- BIOTRONIK Asia Pacific Pte Ltd