Clinical trials: Type 1 Diabetes, completed
Type 1 Diabetes
MICHAEL Method- Fulfilling Individual Potential to Attain Excellence - as a Tool for Improving Metabolic Control and Quality of Life Among Adolescence With Type 1 Diabetes
Type 1 diabetes is the most common childhood disease. Treatment of diabetes requires personal checks of blood sugar levels, injecting insulin, changing eating habits and physical exercise, which requires a real change in the life…
- Trial name
- NCT01691287
- Testing
- Michael Method
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Rabin Medical Center
Drug-specific Antibodies, Diabetes Mellitus
Evaluate the Immunogenicity of a Novel Glucagon Formulation
This study provides information on immunogenicity of Nasal Glucagon (AMG504-1) with regards to the potential development of treatment-emergent anti-glucagon antibodies.
- Trial name
- NCT01959334
- Testing
- Nasal Glucagon (NG), Glucagon IM
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes
Insulin-based Strategies to Prevent Hypoglycemia During Exercise
It has been reported that insulin basal rate reduction initiated at exercise onset can reduce the hypoglycemic risk during exercise.
- Trial name
- NCT02631265
- Testing
- Exercise 1, Exercise 2, Exercise 3
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Use of Diazoxide in Acute Hypoglycaemia
The investigators know that intensive insulin therapy and tight glucose control is associated with reduction of diabetic complications.
- Trial name
- NCT01488136
- Testing
- Diazoxide
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Dundee
Type1diabetes
Check It! 2.0: Positive Psychology Intervention for Adolescents With Type 1 Diabetes
The treatment regimen for type 1 diabetes is complex and demanding, and many adolescents have problems with adherence. The proposed study will pilot test a positive psychology intervention for adolescents with type 1 diabetes…
- Trial name
- NCT02984709
- Testing
- Positive Psychology Intervention, Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Diabetes, Diabetes Mellitus, Type 1
A Survey on Low Blod Sugar Among Insulin-treated Patients With Diabetes
This study is conducted globally. The aim of this study is to describe the proportion of patients with hypoglycaemic episodes and estimate the incidence of various types of hypoglycaemia in the retrospective and prospective…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT02306681
- Testing
- No treatment given
- Where
- 8 sites in Bangladesh, Colombia and 6 more
- Volunteers
- 7,315 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes, Type 2 Diabetes
A Prospective, Randomized, Parallel Crossover Study Demonstrating Subject Wearability and Usability of the I-Port Injection Port
This study investigated wearability and usability of the I-PORT™ Injection Port (I-PORT™), a new disposable injection port through which prescribed medication is injected subcutaneously from a standard syringe or pen.
- Trial name
- NCT00486109
- Testing
- I-Port(TM) Injection Port
- Where
- 5 sites in United States
- Volunteers
- 74 people
- Sponsor
- Patton Medical Devices
Diabetes, Diabetes Mellitus, Type 1
The HEADWIND Study - Part 2
To analyse driving behavior of individuals with type 1 diabetes in eu- and progressive hypoglycaemia while driving in a real car.
- Trial name
- HEADWIND (NCT04569630)
- Testing
- Controlled hypoglycaemic state while driving
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Diabetes, Diabetes Mellitus, Type 1
A Randomised Proof-of-Principle Trial Investigating Pharmacodynamics, Pharmacokinetics, and Safety of NNC0143-0406 in Subjects With Type 1 Diabetes Mellitus
This trial is conducted in Europe. The aim of this trial is to investigate Pharmacodynamics (the effect of the investigated drug on the body) , Pharmacokinetics (the exposure of the trial drug in the body), and Safety of…
- Trial name
- NCT02938572
- Testing
- NNC0143-0406, Insulin Aspart
- Where
- Austria
- Volunteers
- 47 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes, Autoimmune Diabetes
Is the Artificial Pancreas, Without Carbohydrate Counting, Efficient and Safe in an Outpatient Setting
This is a pilot, interventional clinical trial to assess the effectiveness and safety of artificial pancreas (AP) using the ARG algorithm closed-loop system in a monitored 3-day period outpatient study.
- Trial name
- NCT04793165
- Testing
- Non-hybrid closed-loop system with ARG algorithm
- Where
- Argentina
- Volunteers
- 5 people
- Sponsor
- Hospital Italiano de Buenos Aires
Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy
Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective Study
Diabetes mellitus type I is an increasing burden for more and younger children. Therapy should avoid long-term complications as macrovascular diseases and diabetic nephropathy, retinopathy and diabetic neuropathy (DN).
- Conditions
- Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy, Nerve Conduction Study Not Performed
- Trial name
- NCT01512030
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Landeskrankenhaus Feldkirch
Diabetes Mellitus, Type 1
Insulin Lispro 6 Days Versus Insulin Aspart 6 Days in Pump Use
Patients will continue to use their current insulin pump for this study. Patients will receive insulin lispro and insulin aspart during this study.
- Trial name
- NCT01134107
- Testing
- Insulin Lispro 6 Day (6D), Insulin Aspart 6 Day (6D)
- Where
- 15 sites in France, Germany and 1 more
- Volunteers
- 133 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 1
Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Participants With Type 1 Diabetes Mellitus
The purpose of the study is to compare Humalog (Insulin lispro)-recombinant human hyaluronidase (rHuPH20) or Novolog (Insulin aspart)-rHuPH20 to Humalog (Insulin lispro) for the treatment of Type 1 Diabetes Mellitus (T1DM) in…
- Trial name
- NCT01194245
- Testing
- Insulin lispro, recombinant human hyaluronidase PH20, Insulin aspart
- Where
- 19 sites in United States
- Volunteers
- 135 people
- Sponsor
- Halozyme Therapeutics
Type 1 Diabetes
A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes
This study will be conducted primarily to evaluate the effects of CT-868 on glucose homeostasis in participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT05794581
- Testing
- CT-868, Victoza
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Carmot Therapeutics, Inc.
Type 1 Diabetes Mellitus
Islet Transplantation Using Abatacept
Islet transplantation in type 1 diabetics with hypoglycemic unawareness using abatacept as a part of a novel calcineurin-inhibitor-sparing immunosuppressive regimen.
- Trial name
- NCT00276250
- Testing
- Efalizumab, Abatacept, Belatacept
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Emory University
Type 1 Diabetes, Continuous Glucose Monitoring
The Effect of Frequent Continuous Glucose Monitoring Use on Glucose Variability in Preschoolers With Type 1 Diabetes
The purpose of this study is to determine whether continuous glucose monitoring will improve glucose variability as measured by the coefficient of variation of glucose levels in very young children with T1D.
- Conditions
- Type 1 Diabetes, Continuous Glucose Monitoring, Children, Glucose Variability
- Trial name
- NCT04558710
- Where
- Slovenia
- Volunteers
- 339 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Type 2 Diabetes, Diabetic Nephropathy
Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and Nephropathy
Angiotensin type-1 receptor (AT1R) blockers (ARBs) have been recognized recently as regulators of glucose and lipid metabolism in adipocytes and adipose tissue.Moreover telmisartan and irbesartan have been recognized recently as…
- Trial name
- NCT00361023
- Testing
- losartan
- Volunteers
- 25 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetes Mellitus, Type 1
SAFE-AP: Automatic Control of Blood Glucose Under Announced and Unannounced Exercise
Achieving near-normoglycemia has been established as the main objective for most patients with diabetes. Despite growing evidence about the health benefits of regular exercise in diabetes, exercise-associated glycemic imbalance…
- Trial name
- SAFE-AP3 (NCT03577158)
- Testing
- Closed-loop controller with exercise mitigation module, Closed-loop controller without exercise mitigation module, Open-loop insulin infusion system
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Hospital Clinic of Barcelona
Diabetes Mellitus Type 1
Glulisine Pre- and Postmeal
To investigate in type 1 diabetic patients the glucodynamic response to HMR1964 insulin and RHI (HOE31HPR100) injected subcutaneously before and after a standard meal
- Trial name
- NCT00290043
- Testing
- Insulin glulisine
- Volunteers
- 20 people
- Sponsor
- Sanofi
type1diabetes, Adolescent Behavior
Disease Management in Adolescents With Type 1 Diabetes
Adolescence period; It is a transition period of rapid growth, development and maturation in biochemical, physical, social and spiritual terms, which lasts from the beginning of puberty to young adulthood.
- Conditions
- type1diabetes, Adolescent Behavior, Self Efficacy
- Trial name
- NCT06246279
- Testing
- Adaptation to Adolescence and Type 1 Diabetes Management Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Akdeniz University