Clinical trials: Type 1 Diabetes in Adolescence
Type 1 Diabetes
Fast Advanced Closed-Loop Therapy
A double-blind, multinational, multicenter, randomised, 2-period crossover study to assess the efficacy and safety of advanced closed-loop insulin delivery with Minimed 670G 4.0 system comparing Faster Insulin Aspart to Standard…
- Trial name
- FACT (NCT04853030)
- Testing
- Fiasp, Novorapid
- Where
- 2 sites in Austria, Slovenia
- Volunteers
- 30 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Type 1 Diabetes Mellitus
Real-world Study on the Effectiveness and Safety of Control-IQ Technology in Teenagers With Type 1 Diabetes Engaging in Regular Physical Activity
We hypothesize that the use of the Control-IQ system positively influences glycemic control in teenagers with type 1 diabetes during physical activity.
- Trial name
- PED-CIQAcT1ve (NCT06876207)
- Testing
- Tandem t:slim X2 with Control-IQ technology
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Bruno Bombaci
Diabetes Mellitus
Genetics of Type 1 Diabetes in Chinese Adolescents and Youth
primary outcome: To explore the genetic susceptibility of diabetes in Chinese adolescent and youth. secondary outcomes: 1. To classify diabetes by gene detection in Chinese adolescent and youth. 2.
- Trial name
- NCT01938365
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetes Mellitus, Type 1
Safety and Efficacy of Artificial Pancreas With and Without a Meal Detection Module on Glycemic Control in Adolescents With Type 1 Diabetes After a Missed Bolus
Despite current treatments for type 1 diabetes, maintaining blood glucose levels within a good range is a difficult task. A primary source for poor glucose control in adolescents is skipping insulin boluses at mealtimes.
- Trial name
- NCT02909829
- Testing
- Closed Loop Delivery, Closed Loop Delivery with Meal Detection Module, Conventional Pump Therapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University
Type 1 Diabetes
Use of the Paradigm 722 System to Improve Glycemic Control in Adult and Adolescent Subjects With Type 1 Diabetes
The purpose of this study is to determine whether Type 1 Diabetic subjects using the Paradigm 722 System, which is a glucose sensor-augmented insulin pump, can improve glycemic control when compared to subjects using the Paradigm…
- Trial name
- STAR1 (NCT00211510)
- Testing
- Paradigm 722 sensor augmented pump, Paradigm 715 insulin pump
- Where
- 7 sites in United States
- Volunteers
- 146 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes, Diabetic Kidney Disease
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Diabetic kidney disease and cardiovascular disease remain the leading causes of morbidity and mortality in people with type 1 diabetes and are exacerbated with longer duration of diabetes and time outside goal glycemic range.
- Conditions
- Type 1 Diabetes, Diabetic Kidney Disease, Cardiovascular Diseases, Endothelial Dysfunction
- Trial name
- MANATEE-T1D (NCT05065372)
- Testing
- Metformin Hcl 1000Mg Tab, Aminohippurate Sodium 20 % Injection, Iohexol 300 Mg/mL Injectable Solution
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kalie Tommerdahl
Type 1 Diabetes
Family Routines Enhancing Adolescent Diabetes by Optimizing Management
A three month randomized study to examine the potential benefits of sleep extension in tandem with clinical trial on diabetes management in youth with type 1 diabetes.
- Trial name
- FREADOM (NCT02974309)
- Testing
- Sleep Extension, Routine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Arizona
Type 1 Diabetes
Patients Perceptions of Using the "Libre" System Compared With Conventional SMBG in Adolescents With Type 1 Diabetes The Libre Sat Trial
The Libre- flash glucose monitoring system is an episodic real-time data on demand device. This means that patients can measure their glucose level when they choose by scanning the device, while at the same time a sensor…
- Trial name
- NCT02776007
- Testing
- Libre Flash CGMS, Self-Measurement Blood Glucose
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Type 1 Diabetes Mellitus
Pet Ownership and Glucose Control in Type 1 Diabetes
The investigators' long-term goal is to discover novel, inexpensive and feasible strategies to improve the management and well-being of youth with T1DM.
- Trial name
- NCT01733524
- Testing
- Pet Fish, Picture of a fish
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Texas Southwestern Medical Center
Type 1 Diabetes
Use of Continuous Glucose Monitoring System With Intensive Feedback in Adolescents With Poorly Controlled Type 1 Diabetes
The purpose of this study is to determine that continuous glucose monitoring systems (CGMS) with intensive real time feedback about diabetes management from medical staff to the patient will affect motivation and/or behavior, in…
- Trial name
- NCT03020069
- Testing
- CGMS Device, No Device
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- NYU Langone Health
Type 1 Diabetes Mellitus
A Study to Evaluate Symlin in Adolescent Subjects With Type 1 Diabetes Mellitus
This study will be the first evaluation of Symlin in adolescent subjects with type 1 diabetes mellitus and is designed to evaluate the blood levels (pharmacokinetics), biochemical and physiological effects (pharmacodynamics), and…
- Trial name
- NCT00313183
- Testing
- pramlintide acetate
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- AstraZeneca
Type 1 Diabetes
Risk Factors of Metabolic Control in Children and Adolescents With Type 1 Diabetes
Background: Type 1 diabetes is one of the most common chronic illnesses among children and adolescents. Although, intensive medical care is provided for these patients, some of them have poor metabolic control.
- Trial name
- NCT03642470
- Where
- Switzerland
- Volunteers
- 197 people
- Sponsor
- University Children's Hospital, Zurich
Type 1 Diabetes (T1D)
Utilizing Community Health Workers as Diabetes Technology Coaches for Children With Type 1 Diabetes Using Automated Insulin Delivery
This study uses community health workers (CHW) as diabetes technology coaches for African American children using automated insulin delivery systems but have an HbA1c of 8% or higher.
- Trial name
- CHWs AID Youth (NCT07154251)
- Testing
- Community Health Worker
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University Hospitals Cleveland Medical Center
Type 1 Diabetes
Fiasp® Versus NovoRapid® in Children With Type 1 Diabetes on MiniMed 640G Pump With Sensor
This is an exploratory, single-center retrospective cohort real-world study comparing safety and efficacy of Fiasp® versus NovoRapid® when used in the Medtronic MiniMed 640G system in pediatric subjects with Type 1 Diabetes…
- Trial name
- NCT04149262
- Testing
- Fast-acting insulin aspart, Rapid-acting insulin analogues (insulin aspart or insulin lispro)
- Where
- Greece
- Volunteers
- 44 people
- Sponsor
- Aristotle University Of Thessaloniki
type1diabetes
Response to BNT162b2 Vaccine in Adolescents With Type 1 Diabetes
Adolescents with type 1 diabetes may be at increased risk for severe coronavirus disease-2019 (COVID-19) and are therefore prioritized for access to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination.
- Trial name
- NCT05620251
- Testing
- Blood test
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Type 1 Diabetes
Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes
Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate, continuous and intermittent exercise in adolescents living with type 1 diabetes
- Trial name
- CHRONODIAB1 (NCT06803446)
- Testing
- physical test
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Lille University
Diabetes Mellitus, Type 1, Liver Diseases
Liver Function Test Abnormalities in Pediatric Type 1 Diabetes
This cross-sectional study aims to determine the frequency, pattern, and predictors of liver function test abnormalities among children and adolescents with type 1 diabetes mellitus attending Assiut University Children Hospital.
- Trial name
- NCT07807553
- Volunteers
- 101 people
- Sponsor
- Assiut University
Diabetes Mellitus, Insulin-Dependent
Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)
Within 4 weeks after diagnosis of type 1 diabetes, 10 subjects (pubertal males, 12-17 years old) will be randomized to either receive multiple daily injection (MDI) using Lantus insulin, or continuous subcutaneous insulin…
- Trial name
- NCT00357890
- Testing
- Insulin pump therapy, Multiple daily injections using insulin glargine + rapid acting analog
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nemours Children's Clinic
Diabetes Mellitus, Type 1
Optimizing Closed-Loop Control of Type 1 Diabetes Mellitus in Adolescents
The purpose of this study is to use a closed-loop Control-to-Range (CTR) system in adolescents with type 1 diabetes in an outpatient setting, and to evaluate the CTR system's ability to significantly improve blood glucose levels…
- Trial name
- NCT01890954
- Testing
- Diabetes Assistant (DiAs)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Effects of Low-calorie Sweetened Beverage Restriction in Youth With Type 1 Diabetes
This study will investigate whether low-calorie sweeteners (LCS) are helpful or harmful for preventing diabetes complications among children with Type 1 Diabetes (T1D).
- Trial name
- NCT04385888
- Testing
- Low-calorie sweetener restriction
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Allison Sylvetsky (Meni)