Clinical trials: Type 2 Diabetes, completed
Type 2 Diabetes Mellitus
Correlation of Plasma Endothelial Cell Activity With Cardiovascular Events in Patients With Diabetes Mellitus Type 2
CSP 465-B, Correlation of Plasma Endothelial Cell (Basic Fibroblast Growth Factor) Activity With Cardiovascular Events in Patients with Diabetes Mellitus, Type II. Mark Zimering M.D.
- Trial name
- NCT00252525
- Where
- 7 sites in United States
- Volunteers
- 400 people
- Sponsor
- US Department of Veterans Affairs
T2DM (Type 2 Diabetes Mellitus)
The Drug-drug Interaction Study of AJU-A51R1 and AJU-A51R2
To evaluate a pharmacokinetic drug interaction between AJU-A51R1 and AJU-A51R2 in healthy male volunteers.
- Trial name
- NCT04970940
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Diabetes
Microbial Determinants of Dementia Risk in Type 2 Diabetics of Mexican Descent
Type 2 diabetes (T2D) predisposes individuals to neurodegeneration and dementia, including Alzheimer's Disease (AD); yet the link between metabolic and neurodegenerative disorders remains unknown.
- Trial name
- NCT04602650
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Adiposity
GIP/GLP-1 Co-Activity in Subjects With Obesity: Lowering of Food Intake
We aim to delineate the effects of separate and combined infusion of GIP and GLP-1 on food intake, appetite, bone health and fat metabolism in overweight/obese subjects.
- Conditions
- Obesity, Adiposity, Type 2 Diabetes
- Trial name
- GASOLIN (NCT02598791)
- Testing
- IIGI+GIP, IIGI+GLP-1, OGTT
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Diabetes Mellitus, Type 2
Feasibility Trial Using an Inpatient Insulin Dosing Calculator
The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission.
- Trial name
- NCT06206525
- Testing
- Initial insulin dosing calculator
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Type 2 Diabetes
A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus
The purpose of this clinical research study is to learn if BMS-512148 is effective in controlling blood sugar levels as determined by HbA1c and fasting plasma glucose in patients who have been diagnosed with Type 2 diabetes.
- Trial name
- NCT00263276
- Testing
- dapagliflozin, metformin
- Where
- 144 sites in United States, Canada and 2 more
- Volunteers
- 389 people
- Sponsor
- AstraZeneca
Obesity, Type 2 Diabetes Mellitus
GOS and Insulin Sensitivity
Based on our hypothesis that orally administered GOS will be fermented into a SCFA pattern high in acetate and that this will lead to beneficial effects on human substrate and energy metabolism, we aim to address the following…
- Trial name
- NCT02271776
- Testing
- Galactooligosaccharide, maltodextrin
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Kidney Diseases, Diabetic Nephropathies
First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Diabetes
GFB-024 is intended for use in patients with kidney disease such as diabetic nephropathy. This study is the first time GFB-024 has been used in humans.
- Conditions
- Kidney Diseases, Diabetic Nephropathies, Diabetes Complications, Diabetes Mellitus
- Trial name
- NCT04880291
- Testing
- GFB-024
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Goldfinch Bio, Inc.
Type 2 Diabetes Mellitus
Metabolic Activation With Almased for Type 2 Diabetes Patients
Overweight patients with type 2 diabetes are often being treated with an intensified insulin therapy. However, in many cases, even a high insulin dosage (> 100 U per day) does not achieve satisfying metabolic control.
- Trial name
- Almased100 (NCT01680926)
- Testing
- Almased
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- West German Center of Diabetes and Health
Diabetes Mellitus Type 2
A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease
A single center, double-blind, placebo-controlled, randomized, crossover, phase II study to assess the effect of aleglitazar on cardiac energetics and function in patients with uncomplicated type 2 diabetes mellitus and no…
- Trial name
- NCT01680978
- Testing
- aleglitazar
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Hoffmann-La Roche
Diabetic Nephropathy Type 2
Effect of Exercise Therapy on Type II Diabetic Neuropathic Patients
The goal of this Randomized control trial (clinical trial) is to learn about the effect of Exercise therapy on Type II Diabetic Neuropathic Patient in Pakistan ,40-70 year's old patient, will be refer by physicians.
- Trial name
- NCT06332378
- Testing
- Experimental group 1 :Ball training, Experimental group 2 :Frenkel Exercises, Control Group
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Dr. Sobia Hasan
Cardiovascular Disease, Type 2 Diabetes
Effects of Pistachios on Cardiovascular Responses to Stress in Type 2 Diabetes
This study is investigating the effects of three different diets, including a diet with pistachios, on cardiovascular disease risk markers in people with type 2 diabetes.
- Trial name
- Pistachio (NCT00956735)
- Testing
- Pistachio
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Penn State University
Hepatocellular Carcinoma, Type 2 Diabetes
Role of LncRNA H19 in The Regulation of IGF-1R Expression
Hepatocellular carcinoma (HCC) is a common cancer that poses a heavy economic burden on the healthcare system. In Egypt, it is the most common cause of mortality and morbidity-related cancer.
- Conditions
- Hepatocellular Carcinoma, Type 2 Diabetes, Cancer
- Trial name
- NCT04767750
- Testing
- Blood sample collection
- Where
- 2 sites in Egypt
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Type-2 Diabetes, Oral Antidiabetics
Evaluate the Effects of Dapagliflozin in Patients With Type 2 Diabetes
This study will make it possible to better understand the mechanisms responsible for the increase in bad cholesterol levels observed in patients with type 2 diabetes treated with Dapagliflozin, an antidiabetic treatment made by…
- Trial name
- Cinétique DAPA (NCT03269058)
- Testing
- Dapagliflozin
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Type 1 Diabetes, Type 2 Diabetes
User Evaluation of the MiniMed 640G Insulin Pump
This four center international study will include two United Kingdom National Health Service centers, and two centers in Melbourne, Australia.
- Trial name
- NCT01991548
- Testing
- MiniMed® 640G Insulin Pump and Guardian® Link Transmitter
- Where
- 4 sites in Australia, United Kingdom
- Volunteers
- 52 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes Mellitus, Type 2
A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)
This study is designed to examine the efficacy and safety of 2 dose levels of weekly subcutaneously injected albiglutide compared with placebo and an open label reference arm of daily subcutaneous injections of liraglutide, in…
- Trial name
- NCT01733758
- Testing
- Albiglutide 30 mg weekly, Albiglutide 50 mg weekly, Liraglutide 0.9 mg daily
- Where
- 74 sites in Japan
- Volunteers
- 494 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2
MSC and MC in Type 2 Diabetes Mellitus
Cell injury in human islets induced by non-immune mediated inflammation occur in vitro upon hyperglycemia in type 2 diabetes mellitus.
- Trial name
- NCT01719640
- Testing
- infusion of MSCs, infusion MCs, insulin
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Fuzhou General Hospital
Diabetes Mellitus, Non-Insulin-Dependent
Making Ramadhan Fasting a Safer Experience With Technology Study
Type 2 diabetes mellitus (T2DM) is a chronic condition that is one of the major causes of illness, disability, and death in Malaysia with an increasing prevalence.
- Trial name
- NCT02189135
- Testing
- Telemedicine
- Where
- Malaysia
- Volunteers
- 85 people
- Sponsor
- Monash University
Diabetes Mellitus ( Type 1 and Type 2)
Actions & Insights Evaluating a Novel Diabetes Management Solution
Single visit outcome study to obtain qualitative and quantitative data for a new BGMS.
- Trial name
- ASCEND (NCT03638349)
- Where
- 3 sites in United Kingdom
- Volunteers
- 163 people
- Sponsor
- LifeScan Scotland Ltd
Diabetes, Type 2
Study Of Safety And Efficacy Of PF-04991532 In Subjects With Type 2 Diabetes Mellitus
B2611002 is designed to study how safe and effective an investigational medication (PF-04991532) is in people with Type 2 diabetes. Subjects in the study will receive 1 of 5 treatments for 3 months.
- Trial name
- NCT01336738
- Testing
- 150 mg PF-04991532, 450 mg PF-04991532, 750 mg PF-04991532
- Where
- 44 sites in United States, Canada and 5 more
- Volunteers
- 266 people
- Sponsor
- Pfizer
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