Clinical trials: Type 2 Diabetes, completed
Diabetes Mellitus, Type 1
An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes
Closed-loop systems are becoming an integral part of diabetes management. These systems were uniformly proven to improve glycemic control, reduce hyperglycemia and hypoglycemia while modestly reducing HbA1c levels and improving…
- Trial name
- NCT04269668
- Testing
- Medtronic Minimed 670G 3.0 HCL, Medtronic Minimed 670G 4.0 AHCL
- Where
- 2 sites in Germany, Israel
- Volunteers
- 28 people
- Sponsor
- Rabin Medical Center
Hypertension
Glycemic Control Of Carvedilol Versus Metoprolol In Patients With Type II Diabetes Mellitus And Hypertension
To evaluate the effects of two different antihypertensive medications in the drug class of beta-blockers on control of glucose in Type II diabetic patients with high blood pressure.
- Trial name
- NCT00060918
- Testing
- carvedilol, metoprolol
- Where
- 50 sites in United States
- Volunteers
- 1,210 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2
Food As MedicinE for Diabetes
The investigators propose a single-site, open-label, Phase II, community-based randomized clinical explanatory trial to test the efficacy of a medically tailored meal (MTM) interventions for adults with food insecurity and T2DM…
- Trial name
- FAME-D (NCT04828785)
- Testing
- MTM, Food Subsidy
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress, Diabetes Mellitus, Type 2
Decreasing Stress in Diabetes
The purpose of this study is to conduct a randomized controlled trial (RCT) to determine the effects of an online 6-month Mindfulness-based stress reduction (MBSR) intervention compared to an active control Stress Management…
- Conditions
- Stress, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- De-Stress (NCT04016415)
- Testing
- Mindfulness Based Stress Reduction, Stress Management Education
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Milton S. Hershey Medical Center
Type 2 Diabetes Mellitus
Cholesterol Metabolism and Lipid Transfer in Diabetes
The diabetic dyslipidemia is one of the most important risk factor in the development of coronary artery disease. The low density lipoprotein (LDL)-like nanoemulsions is being used to study the clearance of cholesteryl ester and…
- Trial name
- NCT01010035
- Testing
- Plasma kinetic study
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Diabetes, Obesity
Efficacy of tDNA Care on Weight Loss and Metabolic Outcomes in Patients With Overweight, Obesity and Type 2 Diabetes
The aim of this study was to investigate the effectiveness of structured lifestyle intervention following a transcultural diabetes nutrition algorithm (tDNA) care compared to usual diabetes care in patients with overweight…
- Trial name
- NCT03881540
- Testing
- tDNA-MI group, tDNA-CC group, UC group
- Where
- Malaysia
- Volunteers
- 230 people
- Sponsor
- IMU University, Malaysia
Diabetes Mellitus, Type 2, Diabetic Nephropathy
Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy
The goal of this study is to assess whether canagliflozin has a renal and vascular protective effect in reducing the progression of renal impairment relative to placebo in participants with type 2 diabetes mellitus (T2DM), Stage…
- Trial name
- CREDENCE (NCT02065791)
- Testing
- Canagliflozin
- Where
- 575 sites in United States, Argentina and 32 more
- Volunteers
- 4,401 people
- Sponsor
- Janssen Research & Development, LLC
Uncontrolled Diabetes, Diabetes Mellitus Type 2
Efficacy of Diacerein Supplementation on Interleukin-1β, Hs-CRP, TNF-α Levels and Glycemic Control in Uncontrolled Type 2 Diabetes Mellitus Patients at Dr. Mohammad Hoesin General Hospital Palembang
The goal of this clinical trial is to learn if diacerein supplementation can help improve inflammation and glycemic control in adults with uncontrolled type 2 diabetes. It will also study the safety and tolerability of diacerein.
- Trial name
- NCT06912035
- Testing
- Diacerein 50 mg Capsule
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Sriwijaya
Prediabetes
A Lifestyle Change Program to Prevent Type 2 Diabetes
The purpose of this study was to evaluate the effect of a diabetes prevention program provided by nurse practitioners in primary care to adults at risk for diabetes.
- Trial name
- NCT00886340
- Testing
- Enhanced standard care, Lifestyle counseling
- Volunteers
- 58 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 2
Sucralose in Subjects With Diabetes Mellitus Insulin Requesting
To evaluate the acute effect of a preload of sucralose in presence of carbohydrate (HC) available on the glycemic response, postprandial C peptide and satiety in patients with type 2 diabetes mellitus (DM2) in intensive insulin…
- Trial name
- SDMIR (NCT02813759)
- Testing
- Sucralose
- Volunteers
- 10 people
- Sponsor
- Universidad de Valparaiso
Diabetes Mellitus
Insulin Glargine, INITIATE Metabolic and Economic Outcomes of Lantus
To introduce initiation of glargine insulin treatment in primary care based on a patient education program. To show and compare feasibility of group education to individual education program.
- Trial name
- NCT00565162
- Testing
- Insulin Glargine
- Where
- 4 sites in Finland, Netherlands and 2 more
- Volunteers
- 124 people
- Sponsor
- Sanofi
Diabetes Mellitus, Non-Insulin Dependent
Evaluation of SCOUT DS in Subjects With Type 2 Diabetes #2
The primary objective of the trial is to collect SCOUT DS and Hemoglobin A1c measurements of subjects who have been diagnosed with Type 2 diabetes.
- Trial name
- TCOYD2 (NCT01346046)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Type 2 Diabetes
Comparison of Two Titration Programs of Adding Insulin Detemir to OADs in Poorly Controlled Type 2 Diabetes
This study compared the effectiveness and safety of two treatment algorithms for insulin detemir initiation and titration: active titration algorithm (performed by investigator weekly) versus usual titration algorithm (performed…
- Trial name
- NCT01281605
- Testing
- Active titration algorithm, Usual titration algorithm
- Where
- 3 sites in Taiwan
- Volunteers
- 181 people
- Sponsor
- Mackay Memorial Hospital
Type 2 Diabetes
The Effect of a SGLT2 Inhibitor on Glucose Flux, Lipolysis and Exercise in Type 2 Diabetes
The study is a randomised double blind placebo control cross over trial with 4 weeks washout period. The expected duration of participant participation is 103 days.
- Trial name
- SINGLED (NCT04219124)
- Testing
- IMP oral tablet
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Type 2 Diabetes
Necessity for Lipid Lowering Therapy in Type 2 Diabetes Patients
Purpose: To assess prior need for lipid lowering therapy in patients with type 2 diabetes. Background/Hypothesis: At present, lipid lowering therapy, usually with a HMG-CoA reductase inhibitor or "statin", is recommended therapy…
- Trial name
- NCT00639080
- Testing
- Stop lipid lowering therapy (statin)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Endocrine Research Society
Diabetic Neuropathies, Diabetes Mellitus, Type 2
A Study To Evaluate The Effect Of Topiramate On Clinical And Electrophysiological Parameters In Subjects With Diabetic Peripheral Polyneuropathy
The purpose of the study is to evaluate the effect of topiramate on clinical and electrophysiological parameters in patients with diabetic peripheral polyneuropathy.
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Type 2, Polyneuropathies
- Trial name
- NCT00231673
- Testing
- Topiramate
- Volunteers
- 72 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Peripheral Arterial Disease (PAD), Diabete Type 2
Electromagnetic Therapy, Peripheral Vascular Diseases, Diabetes
The goal of this clinical trial was to investigate the efficacy of Low frequency pulsed electromagnetic therapy (LFPEMT) in improving vascular-related quality of life (VQ) and spatiotemporal gait parameters in individuals with…
- Conditions
- Peripheral Arterial Disease (PAD), Diabete Type 2, Gait Abnormality, Quality of Life
- Trial name
- NCT07864805
- Testing
- Low-frequency pulsed electromagnetic therapy plus interval exercise training program
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Ashraf Abdelaal
Diabetes Mellitus Type 2 With Proteinuria, Diabetes Mellitus, Type 2
Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial
The goal of this clinical trial is to determine the feasibility of remote clinical trial conduct in patients with type 2 diabetes and elevated albuminuria.
- Conditions
- Diabetes Mellitus Type 2 With Proteinuria, Diabetes Mellitus, Type 2, Diabetes Mellitus, Diabetes
- Trial name
- Optimize@Home (NCT06094920)
- Testing
- Empagliflozin 10 MG, Finerenone, Withings BPM Connect
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen
Diabetes, Diabetes Mellitus, Type 1
French Observational Survey to Assess Hypoglycaemia in Insulin-treated Diabetic Patients
This non-interventional study is conducted in Europe. The study is both retrospective and prospective. The purpose of the study is to assess the frequency of hypoglycaemia (low blood glucose) in insulin-treated patients with type…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- DIALOG (NCT01628341)
- Testing
- insulin
- Where
- France
- Volunteers
- 4,424 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Type 2
Along-term Study of OPC-262 in Patients With Type 2 Diabetes
The purpose of this clinical study is to evaluate the safety of OPC-262 (2.5 mg and 5 mg) in patients with type 2 diabetes by long-term administration orally for 52 weeks and to evaluate the efficacy of OPC-262
- Trial name
- NCT01634282
- Testing
- OPC-262
- Where
- 7 sites in Japan
- Volunteers
- 222 people
- Sponsor
- Kyowa Kirin Co., Ltd.
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