Clinical trials: Type 2 Diabetes, completed
Type 2 Diabetes
To Evaluate the Response to Glucagon During Hypoglycemia
The purpose of this study is to evaluate the response to Glucagon versus the spontaneous hormonal response to low blood sugar levels in T2DM Patients treated with AZD1656 and Metformin
- Trial name
- NCT00817271
- Testing
- AZD1656, Glucagon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- AstraZeneca
Prediabetes, Vitamin D Deficiency
Oral Cholecalciferol in Prevention of Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is a major public health problem .Prevalence of vitamin D deficiency is also high i.e. 78-96% in different groups of population in north India.
- Trial name
- NCT01436916
- Testing
- oral cholecalciferol + life style counselling
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Type 2 Diabetes
Effect of Education Based on The Health Belief Model on Healthy Lifestyle Behaviors in Individuals With Type 2 Diabetes
This research will be carried out with a randomized controlled experimental design to examine the effect of education based on the Health Belief Model for individuals with Type 2 Diabetes on their health beliefs, self-efficacy…
- Trial name
- NCT05252793
- Testing
- Education based on the health belief model
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Gazi University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Pharmacokinetics/Dynamics of Basal (Continuous) Insulin Infusion Administered Either Intradermally or Subcutaneously
The primary objective of this study will be to assess the PK/PD responsiveness of basal ID administered insulin compared to SC, and to determine the safety and local tolerability of extended (two six-hour periods) microneedle…
- Trial name
- NCT01061216
- Testing
- Intradermal insulin delivery: BD Research Catheter Set, Subcutaneous insulin delivery:ACCU-CHEK Rapid-D Infusion Set
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Becton, Dickinson and Company
Diabetes Mellitus, Type 2
GLucose Monitoring Programme SingaporeE (GLiMPSE)
This phase 1 study is a non-randomized, single-arm, multi-center study that is designed to evaluate the feasibility and acceptability of the flash glucose monitoring system together with a structured education programme in…
- Trial name
- GLiMPSE (NCT03837262)
- Testing
- Flash Glucose Monitoring and structured education
- Where
- 3 sites in Singapore
- Volunteers
- 35 people
- Sponsor
- Singapore General Hospital
Type 2 Diabetes
ALT-801 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus (T2DM)
This is a Phase 1, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety and tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of ALT-801 and its effects on glucose control in…
- Trial name
- NCT05134662
- Testing
- ALT-801
- Where
- 7 sites in United States
- Volunteers
- 55 people
- Sponsor
- Altimmune, Inc.
Diabetes Mellitus, Type 2, Diabetes Mellitus
A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes
The purpose of this study is to investigate the effectiveness and safety of 12 weeks of treatment with R256918 in patients with Type 2 Diabetes Mellitus who are taking metformin.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Endocrine System Diseases, Nutritional and Metabolic Diseases
- Trial name
- NCT00672386
- Testing
- JNJ16269110, Metformin, Dietary Counseling
- Where
- 62 sites in Belgium, Denmark and 9 more
- Volunteers
- 352 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetes Mellitus, Type 2 Diabetes Mellitus
Improving Diabetes in Primary Care (IMPACT)
The goal of our research program is to successfully translate empirical knowledge regarding diabetes treatment and management into sustainable clinical practice.
- Conditions
- Diabetes Mellitus, Type 2 Diabetes Mellitus, Hypertension
- Trial name
- NCT00108927
- Testing
- TRANSLATE
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes, Low-intensity Chronic Inflammation
Vitamin D, C-reactive Protein and Insulin Resistance
Randomized, double blind, placebo-controlled clinical trial of vitamin D supplementation (cholecalciferol, 4,000 IU/day for 6 months, in 104 postmenopausal women with type 2 diabetes mellitus.
- Conditions
- Diabetes, Low-intensity Chronic Inflammation, Insulin Resistance
- Trial name
- NCT01019642
- Testing
- cholecalciferol
- Where
- Mexico
- Volunteers
- 104 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Gestational Diabetes, Type 2 Diabetes Mellitus
Face-it: Health Promotion for Women With Prior Gestational Diabetes
This project focuses on evaluating a health promotion intervention among families where the mother has prior gestational diabetes mellitus (GDM) in the first year after delivery.
- Conditions
- Gestational Diabetes, Type 2 Diabetes Mellitus, Quality of Life
- Trial name
- Face-it (NCT03997773)
- Testing
- Face-it Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 277 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type 2 Diabetes
Evaluation of a Digital Diabetes Self-Management Education and Support Program
The goal of this study is to examine the efficacy of an integrated solution, defined as a combination of the Abbott FreeStyle Libre 14-day CGM sensor and the Omada care team's receipt of real-time, continuous glucose data from…
- Trial name
- NCT05368454
- Testing
- Online Diabetes Self-Management Education and Support (DSMES) Program, Standard of Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Omada Health, Inc.
Type 2 Diabetes, Acute Coronary Event
Tailored Support for Type 2 Diabetes Patients With an Acute Coronary Event After Discharge From Hospital
Background: In type 2 diabetes mellitus patients, an acute coronary event (ACE) may result in a decreased quality of life and increased distress.
- Trial name
- Diacourse (NCT01801631)
- Testing
- Home visits, Consultation by telephone
- Where
- 13 sites in Netherlands
- Volunteers
- 201 people
- Sponsor
- UMC Utrecht
Diabetic Foot, Diabetes Mellitus, Type 2
Foot-Ankle Exercise and Walking Exercise on Diabetes Mellitus Patients
The primary purpose of this study is to determine the effectiveness of foot-ankle exercise and walking exercise on foot neuropathy, stress, and quality of life (QoL) among people with diabetes mellitus (PWDM).
- Conditions
- Diabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2
- Trial name
- NCT06518486
- Testing
- Foot-ankle exercise, Walking exercise, Usual care and health education
- Where
- 5 sites in Indonesia
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Diabetes Mellitus, Type 2, Noninsulin-Dependent Diabetes Mellitus
Effect of Duodenal Mucosal Resurfacing (DMR) Using the Revita System in the Treatment of Type 2 Diabetes (T2D)
The purpose of this study is to demonstrate the efficacy and safety of the Fractyl duodenal mucosal resurfacing (DMR) Procedure using the Revita System compared to a sham procedure for the treatment of uncontrolled type 2…
- Trial name
- NCT02879383
- Testing
- DMR Procedure
- Where
- 11 sites in Belgium, Brazil and 3 more
- Volunteers
- 109 people
- Sponsor
- Fractyl Health Inc.
Dietary Supplement
To Evaluate the Post-Prandial Metabolic Effects of Oligomalt in Adults With T2D and in HAO
The goal of this mechanistic, exploratory study is to compare the effectiveness of Oligomalt to Glucidex 40 after eating in adults with Type 2 Diabetes (T2D) and in otherwise healthy adults with overweight or obesity (HAO).
- Trial name
- LORIS-02 (NCT05963594)
- Testing
- Oligomalt, maltodextrin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Type 2 Diabetes Mellitus
Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus Glimepiride
This study will evaluate the efficacy and safety of vildagliptin 50 mg bid as add-on therapy to metformin plus glimepiride in patients with Type 2 Diabetes (T2D).
- Trial name
- Vildagliptin (NCT01233622)
- Testing
- Vildagliptin
- Where
- 55 sites in Australia, Germany and 7 more
- Volunteers
- 317 people
- Sponsor
- Novartis
Diabetes Mellitus, Non-Insulin-Dependent
MK-1006 Single Dose Study in Japanese Type 2 Diabetes Patients (MK-1006-005)
A single rising dose study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of MK-1006 in Japanese participants with Type 2 Diabetes Mellitus (T2DM).
- Trial name
- NCT00791661
- Testing
- MK-1006
- Volunteers
- 24 people
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes
Rural Area Pharmacist Intervention for Diabetes
The goal of the project is to inform the system leaders regarding the feasibility and utility of having an embedded telehealth-based clinical pharmacist at rural primary care practices for supportive disease management of…
- Trial name
- NCT05761886
- Testing
- telehealth-based clinical pharmacy intervention
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Wake Forest University Health Sciences
Diabete Type 2, Diabetes
The Healthy Eating and Active Living to Reverse Diabetes Pilot Study
The HEAL Diabetes Program is a multicomponent intensive plant-forward healthy eating program designed to reverse diabetes. Several recent studies, most notably the Diabetes UK-funded Diabetes Remission Clinical Trial (DiRECT) in…
- Conditions
- Diabete Type 2, Diabetes, Overweight , Obesity
- Trial name
- HEAL Diabetes (NCT07316569)
- Testing
- Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Tennessee
Adverse Drug Event, Effect of Drug
Research on Human Insulin rDNA Safety and Efficacy in Patients With Type 2 Diabetes Mellitus
Objective: To evaluate the safety and efficacy of Human Insulin rDNA (Insuget) in patients with Type II Diabetes Mellitus. Study Design: Open-label, prospective, observational, single arm, multi-center, post-marketing…
- Conditions
- Adverse Drug Event, Effect of Drug, Type 2 Diabetes Treated With Insulin
- Trial name
- RISE (NCT05161741)
- Testing
- Insulin
- Where
- Pakistan
- Volunteers
- 238 people
- Sponsor
- Getz Pharma
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