Clinical trials: Type 2 Diabetes, completed
Type 2 Diabetes
Development of Self-Regulation in Individuals With Type 2 Diabetes
The purpose of this investigation is to conduct a 12-week study to compare the effects of a self-regulation intervention (SR), in which participants will self-monitor their blood glucose (BG) and adjust dietary intake and…
- Trial name
- NCT00941447
- Testing
- Dietary, Physical Activity, Self-Regulatory Approaches
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Tennessee, Knoxville
Diabetes Mellitus, Type 2
Effects of Exercise Therapy on Ventricular and Endothelial Function in Patients After Coronary Artery Bypass Surgery
The purpose of this study was (1) to compare the peak exercise capacity and left ventricular diastolic function between patients with and without diabetes and (2) to investigate the interrelation among peak oxygen consumption…
- Trial name
- NCT01990638
- Testing
- exercise capacity test
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan University Hospital
Major Depressive Disorder, Depression
Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
This study will examine if brain insulin resistance is a feature of depression in humans using magnetic resonance imaging (MRI) measures sensitive to brain insulin action.
- Trial name
- NCT05571878
- Testing
- Humalog, Saline nasal spray
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Type 1 Diabetes
Two Way Crossover Closed Loop Study Insulin vs Insulin and Pramlintide
The purpose of this study is to test how well a new investigational closed loop system manages your blood sugar with the ability to deliver insulin and pramlintide.
- Trial name
- NCT06422325
- Testing
- MPC closed-loop system in insulin only mode, MPC closed-loop system in insulin/pramlintide mode
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Oregon Health and Science University
Diabetes Mellitus, Type 2
Computer-assisted Diabetes Self-management Interventions
This project evaluates the effectiveness of different aspects of a program to assist type 2 diabetes patients with dietary changes.
- Trial name
- NCT00006163
- Testing
- Personalized Self-management, Community Resources
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
The Effect of Viscous Fiber on Glycemic Control in Individuals With Diabetes
Purpose of Study (The Effect of Viscous Fiber on Glycemic Control (VF \& GC) in Individuals with Diabetes Mellitus. According to the World Health Organization, about 347 million individuals are living with diabetes.
- Trial name
- VF&GC (NCT02629263)
- Testing
- Viscous Fiber
- Where
- Canada
- Volunteers
- 1,394 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetes Mellitus, Type 2
Understanding and Improving Diabetes Care for Ethnic Minorities
In this study, we are testing the effectiveness of an intervention known as "Coached Care" to improve health outcomes and quality of care of patients being treated for type 2 diabetes, particularly patients in underserved…
- Trial name
- R2D2C2 (NCT01123239)
- Testing
- Coached Care, Standard Diabetes Education
- Where
- 3 sites in United States
- Volunteers
- 540 people
- Sponsor
- University of California, Irvine
Type 2 Diabetes Mellitus, Insulin Resistance
Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
The role of individual leukocyte populations in type 2 diabetes (T2D) and immunometabolism in general represent important gaps in knowledge to better understand the etiopathogenesis of T2D.
- Trial name
- NCT02597101
- Testing
- Metformin, saxagliptin, AZD9668
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Nick Giannoukakis, PhD
Continuous Glucose Monitoring, Quality of Life
Influence of Continuous Glucose Monitoring on Quality of Life in People With Type 2 Diabetes Mellitus
Background: Diabetes Mellitus (DM) is a chronic disease that affects millions of people worldwide. More than 95% of cases are type 2 diabetes mellitus (T2DM).
- Conditions
- Continuous Glucose Monitoring, Quality of Life, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- Glucocavi (NCT06716671)
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Diabetes Mellitus
Self-Management of Type-2 Diabetes Using a Mobile Application
Diabetes Mellitus (DM) is a global health emergency, since its prevalence has become alarming in many countries in the previous years.
- Trial name
- NCT05027334
- Testing
- DiaMon - Mobile Application for Type 2 Diabetes mellitus and pre-diabetes
- Where
- Mauritius
- Volunteers
- 25 people
- Sponsor
- University of Mauritius
Type 2 Diabetes Mellitus, Obesity
Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus
Controlling the glycemic impact of foodstuffs (by reducing the glycemic load of the diet by using soluble dietary fibres) may reduce the glycemic or insulinemic response.
- Trial name
- NCT01163006
- Testing
- Polydextrose and soluble gluco fibre
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes Mellitus
Evaluate the Drug-drugs Interaction Between Lobeglitazone 0.5mg and Empagliflozin 25mg
A Clinical Trial to evaluate the Pharmacokinetics and Tolerability of CKD-398
- Trial name
- NCT04869800
- Testing
- CKD-398, CKD-501, D745
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Type 2 Diabetes
SAFEGUARD: Pleiotropic Effects of Incretin Based Therapies
The aim of this study is to detail the (mechanisms underlying the) actions of the GLP-1 receptor agonists and DPP-4 inhibitors on the cardiovascular, renal and gastrointestinal systems in patients with Type 2 Diabetes Mellitus.
- Trial name
- NCT01744236
- Testing
- Liraglutide, Sitagliptin, Exenatide
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
CKD - Chronic Kidney Disease, Diabetes Mellitus Type 2
Evaluation of the Risk of Heart Failure in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus
The goal of this study, performed entirely with computer programs, is to learn if using a combination of two drugs works better than using one alone, in the treatment of people with chronic kidney disease and type 2 diabetes…
- Trial name
- NCT07719621
- Where
- Spain
- Volunteers
- 100,000 people
- Sponsor
- Aeterna Medical Solutions SL
Cardiovascular Disease, Diabetes Mellitus, Type 2
Researching Cardiovascular Events With a Weekly Incretin in Diabetes (REWIND)
The purpose of this trial is to assess whether dulaglutide can reduce major cardiovascular events and other serious outcomes in persons with type 2 diabetes, when added to their anti-hyperglycemic regimen.
- Trial name
- REWIND (NCT01394952)
- Testing
- Dulaglutide
- Where
- 300 sites in United States, Argentina and 23 more
- Volunteers
- 9,901 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus
Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance
The study is being conducted to find out why too much fat in your blood stream may cause insulin resistance in your muscles. Insulin is the hormone, produced normally by your body, which causes your blood sugar to return to…
- Trial name
- NCT01240252
- Testing
- Human insulin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2
Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021)
The purpose of this clinical study is to determine the safety and efficacy of an investigational drug in patients with type 2 diabetes mellitus.
- Trial name
- NCT00087516
- Testing
- Sitagliptin (MK0431), Sitagliptin, Metformin - Rescue
- Volunteers
- 741 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Efficacy and Safety of Linagliptin in Combination With Insulin in Patients With Type 2 Diabetes
The objective of the current study is to investigate the efficacy, safety and tolerability of linagliptin (5 mg / once daily) compared to Placebo during long term treatment (52 weeks and longer) in combination with basal insulin…
- Trial name
- NCT00954447
- Testing
- Linagliptin
- Where
- 169 sites in United States, Argentina and 17 more
- Volunteers
- 1,263 people
- Sponsor
- Boehringer Ingelheim
Dyslipidemia
Effect of CP-778,875 on HDL-C in Subjects With Abnormal Lipid Levels and Type 2 Diabetes.
To assess the effect of CP-778,875 on HDL-C cholesterol in adult subjects with dyslipidemia and type 2 diabetes
- Trial name
- NCT00326326
- Testing
- CP-778,875
- Where
- 31 sites in United States
- Volunteers
- 84 people
- Sponsor
- Pfizer
Type2 Diabetes
A Study of 3mg Once Every Two Weeks Administration of Efsubaglutide Alfa Injection in Type 2 Diabetes Patients.
This is a study to evaluate the impact and efficacy of Efsubaglutide Alfa injection 3mg QoW on the treatment of type 2 diabetes patients with poor glycemic control after dietary and exercise intervention.
- Trial name
- NCT06849843
- Testing
- Efsubaglutide Alfa Injection
- Where
- 10 sites in China
- Volunteers
- 59 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
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