Clinical trials: Type 2 Diabetes, completed
Prediabetic State
A Study of Attitudes About the Risk of Developing Type 2 Diabetes
Diabetes mellitus (DM) type 2 is well recognized as a major cause of morbidity and mortality in the United States, as well as a significant contributor to health disparities within the population.
- Trial name
- NCT00323349
- Testing
- Oral Glucose Tolerance Testing, Education tailored to learning style preferences
- Where
- 2 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Type 2 Diabetes Mellitus
Metabolic Effects of Alcohol
The hypotheses to be tested are 1) the use of alcohol in the form of wine with the evening meal will lower plasma glucose during the night and result in lower fasting plasma glucose the next morning; 2) the chronic use of alcohol…
- Trial name
- NCT00167115
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Bantle, John P., MD
Type 2 Diabetes Mellitus
Study of Muraglitazar Versus Pioglitazone in Type 2 Diabetes
The purpose of this study is to compare Muraglitazar and Pioglitazone in patients with Type 2 Diabetes. Both the safety and blood sugar lowering effects of these treatments will be studied.
- Trial name
- NCT00106808
- Testing
- Muraglitazar, Pioglitazone
- Where
- 195 sites in United States, Argentina and 12 more
- Volunteers
- 1,440 people
- Sponsor
- Bristol-Myers Squibb
Type 2 Diabetes Mellitus, Insulin Resistance
Impact of Overfeeding and Following Exercise Training in Individuals With and Without Increased Risk of Type 2 Diabetes
Low birth weight (LBW), a marker of impaired fetal growth is an independent and strong risk factor for type 2 diabetes (T2D). A western lifestyle characterized by a surplus of calories, and/or a low physical activity level…
- Conditions
- Type 2 Diabetes Mellitus, Insulin Resistance, Dyslipidemia
- Trial name
- NCT02982408
- Testing
- High carbohydrate overfeeding, Exercise, Normal physical activity
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Peripheral Diabetic Neuropathy
Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical Trial
This study determines the effects of moderate physical activity on early symptoms of peripheral diabetic neuropathy in type-II diabetes. Most of the literature shows the impact of physical activity to manage/controlling diabetes.
- Trial name
- NCT05491850
- Testing
- Moderate Physical Activity for Peripheral Diabetic Neuropathy
- Where
- Pakistan
- Volunteers
- 17 people
- Sponsor
- Riphah International University
High Risk Hypertensive Patients
Study to Improve Quality of Care and Patient Health in the Field of Cardiovascular Risk Factors in General Practice
Observational studies performed in France and abroad in hypertensive patients at high cardiovascular risk have shown a wide gap between the therapeutic targets reached in ambulatory patients and those set by guidelines.
- Trial name
- ESCAPE (NCT00348855)
- Testing
- Cardiovascular drugs strategies, Compliance, Exercise
- Where
- 2 sites in France
- Volunteers
- 1,836 people
- Sponsor
- Collège National des Généralistes Enseignants
Type 1 Diabetes, Type 2 Diabetes
Feasibility Study - Integrated Sensor and Infusion Set. Trial III
The purpose of this study is to collect performance data on the Integrated sensor and infusion set during 3 days of use and demonstrate performance adequacy of the integrated sensor and infusion set with glucose sensing and…
- Trial name
- NCT01773668
- Testing
- Integrated sensor and infusion set.
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Medtronic Diabetes R&D Denmark
Diabetes Mellitus Type 2
A Study to Evaluate the Long-Term Safety and Tolerability of GK Activator (2) in Patients With Type 2 Diabetes.
This study will evaluate the long-term safety and tolerability of GK Activator (2) at doses ranging from 25mg - 100mg po bid, administered alone or in combination with metformin, in patients with type 2 diabetes.
- Trial name
- NCT00316758
- Testing
- GK Activator (2), Metformin
- Where
- 58 sites in United States, Australia and 8 more
- Volunteers
- 259 people
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetes, Major Depressive Disorder
A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary Care
The study involves a 32-week randomized controlled trial in primary care of a comprehensive diabetic and depression intervention in patients with type 2 diabetes and comorbid MDD, compared to a group treated with usual care for…
- Trial name
- NCT00939250
- Testing
- Diabetes and depression intervention, Diabetes intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Laparascopic Sleeve Gastrectomy, Obesity & Overweight
Impact Of Laparoscopic Sleeve Gastrectomy On Obesity-Related Comorbidities In Patients Over 65 Years
This study compares laparoscopic sleeve gastrectomy (a type of weight-loss surgery) with non-surgical care in adults aged 65 or older who have severe obesity and related health problems like type 2 diabetes, high blood pressure…
- Conditions
- Laparascopic Sleeve Gastrectomy, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07437716
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Structured Dietary Counseling
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Type 2 Diabetes
Insulinotropic Effect of GLP-1 and GIP After Dexamethasone
In this study we examine whether inducing insulin resistance by dexamethasone in healthy volunteers will lead to a decreased insulinotropic effect of the hormones GLP-1 and GIP.
- Trial name
- NCT02235584
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Diabetes, Diabetes Mellitus, Type 2
Mindfulness IN-home for Diabetes and Sleep Health
The study investigates the effects of a mindfulness intervention on sleep and subsequent cardio-metabolic risk in an adult Atlanta population aged 18 and older.
- Trial name
- MINDS (NCT04160078)
- Testing
- Mindfulness-based stress reduction (MBSR) Intervention
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Emory University
Diabetes Mellitus Type 2, Non-alcoholic Fatty Liver Disease
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients
This study involves research about an investigational medicine called Amlexanox. The reason for this study is to find out how Amlexanox can improve type 2 diabetes, insulin resistance, obesity and non-alcoholic fatty liver…
- Conditions
- Diabetes Mellitus Type 2, Non-alcoholic Fatty Liver Disease, Obesity
- Trial name
- NCT01975935
- Testing
- Amlexanox
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Michigan
Type-2 Diabetes
GLP-1 and Oxyntomodulin Release in Relation to Diet in Type 2 Diabetes Patients.
The aim of this trial was to assess glycemic control and incretin release in subjects affected by type-2 diabetes, a condition in which GLP-1 release is impaired.
- Trial name
- VAS (NCT04105608)
- Testing
- High-fiber vegetarian meal, Mediterranean-like meal
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Antonio Di Mauro
Type 2 Diabetes Mellitus
Post-Marketing Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Ipragliflozin in Combination With GLP-1 Receptor Agonists in Japanese Patients With Type 2 Diabetes Mellitus (T2DM)
Purpose of this study is to evaluate the Long-term Safety, Tolerability, and Efficacy of Ipragliflozin in Combination with GLP-1 Receptor Agonists in Japanese Patients with Type 2 Diabetes Mellitus Who Have Inadequate Glycemic…
- Trial name
- NCT02291874
- Testing
- Ipragliflozin
- Where
- 6 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc
Type 2 Diabetes Mellitus, Chronic Kidney Disease
A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease
To assess the safety and efficacy of up to two REACT injections given 6 months (+4 weeks) apart and delivered into the biopsied kidney using a percutaneous approach in participants with Type 2 Diabetes Mellitus (T2DM) and Chronic…
- Trial name
- NCT02836574
- Testing
- Renal Autologous Cell Therapy (REACT), Renal Biopsy
- Where
- 16 sites in United States
- Volunteers
- 83 people
- Sponsor
- Prokidney
Diabetes Mellitus, Type 2
A Research Study Looking Into Blood Levels of the Medicine NNC0519-0130 in the Body in Participants With Normal or Reduced Kidney Function
NNC0519-0130 is a new medicine to improve the treatment options for people living with type 2 diabetes and people with overweight.
- Trial name
- NCT06370819
- Testing
- NNC0519-0130
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus Type 2
Vildagliptin Versus Sitagliptin - Differences in Fasting Plasma Glucose Lowering Efficacy
This study is designed to assess the potential difference in Fasting Plasma Glucose (FPG) lowering efficacy between the two DPP-4 inhibitors vildagliptin and sitagliptin, both after a two weeks treatment on top of metformin.
- Trial name
- FPG-VISIT (NCT01398592)
- Testing
- Vildagliptin, Sitagliptin
- Where
- 15 sites in Germany
- Volunteers
- 187 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus
Evaluating the Impact of a Technologically-Enhanced Personal Coaching Program on Hemoglobin A1c in Type 2 Diabetics
Participants diagnosed with Type 2 diabetes receive personal coaching from a Certified Diabetic Educator (CDE) over a six-month period. The coaching program is enhanced using an mobile application and care management platform.
- Trial name
- NCT03719911
- Testing
- Live diabetes coaching program
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Welkin Health
Gestational Diabetes, Type 2 Diabetes
Preventing T2DM After GDM With Immediate Postpartum Screening
The overall goal of this proposal is to create and test an implementation protocol for in-hospital immediate postpartum diabetes screening for postpartum patients with pregnancies affected by GDM.
- Trial name
- NCT06457139
- Testing
- Glucose tolerance test (2 hour), Active Comparator
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Massachusetts, Worcester
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