Clinical trials: Type 2 Diabetes, completed
Type 2 Diabetes
Effect of Pioglitazone on TIMP-3 and TACE in Type 2 Diabetes
Background: Pioglitazone has been shown to have potent anti-inflammatory as well anti-atherosclerotic effects. However, the mechanisms by which pioglitazone exerts these effects are not clear.
- Trial name
- PIO-TACE (NCT01223196)
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetes Mellitus
Study of Combination Therapy With SYR-322
To determine the efficacy and safety of SYR-322 (alogliptin) 25-mg, once daily (QD), in patients with diabetes when used in combination with insulin.
- Trial name
- NCT01521962
- Testing
- Alogliptin, Insulin
- Where
- 33 sites in Japan
- Volunteers
- 67 people
- Sponsor
- Takeda
Diabetes Mellitus, Type 2, Gait Disorders, Neurologic
Balance and Motion Coordination Parameters Can be Improved in Patients With Type 2 Diabetes
Diabetes mellitus type II (DMII) causes many complications, including retinopathy and peripheral neuropathy. These complications are well understood and believed to contribute to gait instability and increase the risk of falls.
- Trial name
- NCT04484480
- Testing
- Balance training
- Where
- Poland
- Volunteers
- 77 people
- Sponsor
- Medical University of Warsaw
Diabetes, Diabetes Mellitus, Type 2
A Trial to Assess the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Oral Semaglutide in Healthy Male Japanese and Caucasian Subjects
This trial is conducted in Asia. The aim of the trial is to investigate the pharmacokinetics (the exposure of the trial drug in the body), pharmacodynamics (the effect of the investigated drug on the body), safety and…
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT02161588
- Testing
- semaglutide
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus, Obesity
A Trial of Two Diets for Weight and Diabetes Management
The purpose of this study is to determine whether a low-fat or low-glycemic load diet is more effective for controlling weight and blood glucose in persons with type 2 diabetes.
- Trial name
- Two-for-2 (NCT00729196)
- Testing
- Lifestyle Modification
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes
Impact of Breakfast Composition on Glycemic and Incretin Responses in Individuals With Type 2 Diabetes
This study examined the effect of a high protein or high carbohydrate breakfast on the glucose and insulin response following the breakfast meal, as well as the subsequent response following the lunch meal.
- Trial name
- NCT02180646
- Testing
- High protein breakfast, High carb breakfast
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Diabetes Mellitus Type 2, Hyperglycemia
Efficacy of GLP-1 Infusion in Comparison to an Insulin Infusion Protocol to Reach Normoglycemia Type 2 Diabetic Patients
The aim of the investigators study was to compare for the first time efficacy and safety of intravenously administered GLP-1 with an established intravenous insulin regimen in hyperglycaemic type 2 diabetic patients.
- Trial name
- NCT00859079
- Testing
- GLP-1, Human regular insulin intravenously
- Where
- Austria
- Volunteers
- 8 people
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Type 2
Study to Assess Safety and Effect of a Prebiotic Fiber Meal Replacement Shake in Individuals With Type 2 Diabetes
This study is a double-blind, randomized, trial of a commercially available meal-replacement shake versus a placebo control designed to evaluate the impact on quality of life, safety, and tolerability.
- Trial name
- NCT05110703
- Testing
- Supergut, Dietary guidelines
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Uplifting Results Labs Inc.
Diabetes Mellitus, Type 2
Gastric Emptying - Implications for the Pathogenesis of Type 2 Diabetes
People of black African and Caribbean descent have a greater risk of developing type 2 diabetes than white Europeans. The aim of this study is to increase our knowledge of how the condition may arise, and what underlies this…
- Trial name
- NCT03864562
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Type 2 Diabetes
The Role of Amylin and Incretins on Postprandial Metabolisms in Adolescents With Type 2 Diabetes Mellitus (T2DM).
To study postprandial metabolism in lean, obese and T2DM adolescents using a mixed meal challenge. Specifically we will be measuring the following parameters of postprandial metabolism: 1.
- Trial name
- NCT00361946
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Congestive Heart Failure, Type 2 Diabetes Mellitus
Liraglutide and Heart Failure in Type 2 Diabetes
Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with insulinotropic properties. Apart from the glycemic actions, cardiovascular effects by GLP-1 have recently been reviewed.
- Trial name
- NCT01425580
- Testing
- liraglutide, glimepiride, Metformin
- Where
- 2 sites in Sweden
- Volunteers
- 62 people
- Sponsor
- Thomas Nystrom
Diabetes, Gestational, PreDiabetes
A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes
This study is testing whether daily metformin for 1 year postpartum can reduce risk of diabetes in patients who had gestational diabetes.
- Conditions
- Diabetes, Gestational, PreDiabetes, Diabetes Mellitus, Type 2
- Trial name
- NCT05280496
- Testing
- Metformin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tufts Medical Center
Diabetes, Diabetes Mellitus, Type 2
Liraglutide or Insulin in Real Life Usage in Patients With Diabetes Mellitus Type 2
This study is conducted in Europe. The intention of this health service research study is to obtain data from daily routine to evaluate the quality of life and the costs of the disease for patients with type 2 diabetes mellitus.
- Trial name
- NCT01484262
- Testing
- liraglutide, insulin
- Where
- Germany
- Volunteers
- 1,344 people
- Sponsor
- Novo Nordisk A/S
Non Insulin Dependent Diabetes
Curcumin Supplementation and Patients With Type 2 Diabetes
Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Various kinds of antidiabetic drugs have been developed, but most of them have side effects.
- Trial name
- NCT02529982
- Testing
- Curcumin
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- National Nutrition and Food Technology Institute
Diabetes Mellitus, Type 2
Pilot for the Analysis of Usability in the Use of the Diacare Platform for People With Type 2 DM and Their Professionals
The objective of this study is to evaluate the usability, utility and feasibility of the Diacare platform and the ability of users to use the platform and receive valuable information from it to help address the management of…
- Trial name
- NCT04244110
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Peripheral Diabetic Neuropathy
Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy
Type 2 DM subjects having numbness, tingling and paresthesia in hands and feet (neuropathy) will be recruited. Screening of neuropathy will be done by Michigan screening instrument.
- Trial name
- RCT (NCT06131918)
- Testing
- Resveratrol, Alpha lipoic acid, Super oxide dismutase, Resveratrol, Alpha lipoic acid
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Khyber Medical University Peshawar
Type 2 Diabetes Mellitus
Phase III Trial to Evaluate the Efficacy and Safety of Initial Combination Therapy With Gemigliptin 50mg q.d and Metformin q.d
The objective of this study is to evaluate efficacy and safety of initial combination therapy with Gemigliptin 50mg q.d and Metformin q.d compared with either monotherapy in treatment naïve patients with type 2 diabetes, In other…
- Trial name
- NCT01787396
- Testing
- Gemigliptin 50mg, Metformin
- Where
- South Korea
- Volunteers
- 433 people
- Sponsor
- LG Life Sciences
Coronary Artery Disease, Diabetes Mellitus, Type 2
Cardiovascular Oscillations in Coronary Patients With and Without Type 2 Diabetes
Coronary artery disease (CAD) and diabetes mellitus (DM) may promote alterations in heart responses during exercise or postural maneuver.
- Trial name
- NCT02050399
- Testing
- Isometric exercise
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Coronary Artery Disease, Type II Diabetes Mellitus
Innovative Strategies For Risk Reduction Following CABG
Background: Treatment targets for cardiac risk factor reduction are not being met. Therefore, there is a need for new strategies to assist patients in meeting these goals.
- Trial name
- NCT00462436
- Testing
- Consumption of Dietary Portfolio
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Unity Health Toronto
Diabetes Mellitus, Type 2
Delish Study: Diabetes Education to Lower Insulin, Sugars, and Hunger
Type 2 diabetes mellitus (T2DM) is the most expensive chronic disease in the U.S. Lifestyle modification is central to T2DM management, but long-term adherence to dietary recommendations is difficult.
- Trial name
- Delish (NCT03207711)
- Testing
- Carbohydrate-restricted diet, Mindfulness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
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